Antiretroviral News and Research

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Rockefeller scientists reveal how HIV strains escape broadly neutralizing antibodies

Broadly neutralizing antibodies (bNAbs) are among the most promising new treatments for HIV, offering the potential to forego traditional daily dose of antiretroviral drugs.

11 May 2026

New study tracks HIV care after hospital discharge statewide

Sarah Rutstein, MD, PhD, and Thibaut Davy‑Mendez, PhD, MSPH, with the Institute for Global Health and Infectious Diseases have received an R01 from the National Institute of Mental Health (NIMH) at the National Institutes of Health (NIH).

6 May 2026

New discovery challenges a decades-old assumption in HIV biology

Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect resting immune cells.

6 May 2026

Cellular aging in immune cells signals early onset of cognitive depression

Blood tests measuring the aging of certain white blood cells can predict cognitive and mood-related symptoms of depression, rather than physical symptoms.

4 May 2026

Did life-saving HIV drugs unintentionally fuel a syphilis comeback?

The introduction of HAART for HIV has coincided with a syphilis resurgence, suggesting unintended public health trade-offs from this medical breakthrough.

27 Apr 2026

WHO congratulates The Bahamas for eliminating mother-to-child transmission of HIV

In a landmark achievement for Caribbean public health, the World Health Organization (WHO) congratulates The Bahamas for becoming the latest Caribbean nation to be certified as having eliminated the mother-to-child transmission of HIV.

23 Apr 2026

Availability of HIV treatments contributed to a resurgence in syphilis

A study in Health Economics uncovered an unintended consequence of a major medical breakthrough: while the availability of HIV treatments in the late 1990s dramatically improved survival, they also contributed to a resurgence in syphilis, a sexually transmitted infection.

22 Apr 2026

Study creates genetic roadmap of how HIV virus interacts with human cells

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body.

20 Apr 2026

Antiretroviral therapy reduces biological aging in people living with HIV

A major study presented today at ESCMID Global 2026 has found that antiretroviral therapy (ART) reduces accelerated biological ageing in people with HIV (PWH) by nearly four years, a finding that could transform how clinicians monitor HIV treatment and long-term health outcomes.

20 Apr 2026

Study reveals immune changes in HIV and HCV coinfected patients

Human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfection leads to severe systemic inflammation, increasing non-AIDS morbidity and mortality risk. CD39 ectoenzyme on T-cells, which catalyzes the conversion of pro-inflammatory purines to immunosuppressive adenosine, plays an important role in inflammation control.

28 Mar 2026

Researchers explore "block and lock" strategy for functional HIV cure

For millions of people living with HIV, a daily regimen of medications is a lifelong necessity. If they stop taking the drugs-commonly referred to as antiretroviral therapy-the virus usually rushes back within weeks.

23 Mar 2026

New method creates longer lasting CAR T cells for cancer therapy

A research team led by Albert Einstein College of Medicine scientists has developed a new strategy to engineer immune cells that dramatically prolongs their effectiveness after being infused into patients to fight cancer and HIV, addressing a major limitation of current treatments.

13 Mar 2026

AI pinpoints why vaccine responses vary globally

How people with compromised immune systems respond to vaccines is an important area of immunological research. A new study led by York University found that not only could machine-learning models accurately pinpoint differences in healthy controls and those living with HIV, but also found outliers in both groups that provide fascinating glimpses into the complex nature of the immune system and what personalized medicine could look like in the future, accounting for variables such as age, comorbidities and genetics.

4 Mar 2026

New HIV-seq tool advances understanding of persistent viral reservoirs

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and transmission.

3 Mar 2026

Single-cell RNA sequencing reveals accelerated T cell aging in viral infections

A new research paper was published in Volume 18 of Aging-US on February 8, 2026, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV."

19 Feb 2026

Enhanced natural killer cells show promise for HIV remission

More than 30 million people with HIV must take antiretroviral therapy (ART) medications daily to keep the virus under control, according to the Joint United Nations Programme on HIV/AIDS (UNAIDS).

5 Feb 2026

Immune dysfunction persists after combined TB and HIV therapy

The immune system remains seriously out-of-whack – in an inflammatory state of overactivation and impaired functionality – following the international gold standard for treating people with latent tuberculosis (TB) and HIV, a team at Texas Biomedical Research Institute reports in Nature Communications.

14 Jan 2026

Study reveals genetic signatures linked to HIV-related cognitive impairment

Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled.

14 Jan 2026

Expanded HIV treatment dramatically reduced orphanhood rates in Uganda

The scale-up of HIV treatment and prevention programs has led to remarkable declines in orphanhood rates in Rakai, Uganda, according to a new study at Columbia University Mailman School of Public Health.

7 Jan 2026