Brain Cancer News and Research

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There are two main types of brain cancer. Primary brain cancer starts in the brain. Metastatic brain cancer starts somewhere else in the body and moves to the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Also called glioma, meningioma.

Study potential new therapeutic strategy for patients with ATRX-mutant gliomas

A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of the most common genetic alterations in glioma rewires the cancer cell genome to fuel tumor progression, suggesting a potential new therapeutic strategy for patients with ATRX-mutant gliomas.

1 Jul 2026

CAR-T cell therapy shows potential to eliminate aggressive glioblastoma

A study led by a researcher based at King's College London and McMaster University in Canada reveals how CAR-T cell therapy, a treatment that engineers a patient's own immune cells to recognize and attack cancer, could be used to treat glioblastoma.

1 Jul 2026

Dual-target CAR-T therapy shows promise against aggressive brain tumors

Researchers at McMaster University have developed a new cancer immunotherapy strategy that can simultaneously attack deadly brain tumors and the immune cells that help them grow.

1 Jul 2026

First-in-human trial tests safer T-cell therapy for pediatric brain cancers

Researchers report encouraging early results from a first-in-human clinical trial led by Children's National using a new T-cell immunotherapy for children and young adults with some of the deadliest brain tumors, including diffuse intrinsic pontine glioma (DIPG) and relapsed central nervous system (CNS) tumors.

30 Jun 2026

Study uncovers sex-specific immune pathway driving glioblastoma growth

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory models, pinpointing an immune pathway that fuels tumor growth only in females.

23 Jun 2026

Sugar-coated nanoparticles extend survival in aggressive glioblastoma mouse model

Researchers at Oregon State University have potentially found a new way to treat the most aggressive form of brain cancer, glioblastoma, whose two-year survival rate is less than 30%.

23 Jun 2026

Preoperative radiation boosts immunotherapy response in brain metastases

A new study led by researchers at The University of Texas MD Anderson Cancer Center demonstrated that pre-operative radiation therapy for brain metastases not only targets tumor cells directly but also can activate immune pathways that can make tumors more receptive to immunotherapy.

17 Jun 2026

Dual-target CAR T therapy triggers broad immune response in brain cancer

Dual-target CAR T cell therapy for recurrent glioblastoma (GBM), delivered directly into the cerebrospinal fluid (CSF), triggers a broad immune response, with natural killer (NK) cell activation linked to better patient outcomes and longer overall survival.

15 Jun 2026

Novel analysis identifies unique proliferation gene alterations in diverse cancer patients

New research to be presented today (Monday) at the annual conference of the European Society of Human Genetics shows that a cancer patient's genetic ancestry can have a significant effect both on how their disease progresses and their survival. In the largest study of its kind, researchers examined nearly 1,900 specific genetic changes in tumors in order to measure whether certain mutations were more common in patients with different historic geographic origins.

15 Jun 2026

Major NIH grant helps establish the Oklahoma Center of ImmunoEngineering

The University of Oklahoma has received an $11.5 million award from the National Institutes of Health to establish the Oklahoma Center of ImmunoEngineering, a new research center designed to accelerate the study and treatment of diseases rooted in the immune system.

12 Jun 2026

Low-methionine diet shows promise against aggressive brain tumors

An unexpected lab observation led a team of scientists to discover how diet can influence survival in animal models of glioma, one of the most aggressive and deadly forms of brain cancer.

10 Jun 2026

Brain injury survivors face higher risk of brain cancer death

Daniel Daneshvar, MD, PhD, director of the HealthSpan Lab and Chief of the Department of Physical Medicine and Rehabilitation at Mass General Brigham, and Charlotte Luster, of the HealthSpan Lab, are the senior and lead authors of a paper published in Neuroepidemiology, "Brain Cancer Mortality following Traumatic Brain Injury (TBI): A TBI Model Systems Study."

10 Jun 2026

Study validates research models for tracking circular extra-chromosomal DNA

Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off from a glacier.

5 Jun 2026

Drug-filled nanofibers offer potential breakthrough treatment for brain cancer

Researchers with the University of Cincinnati and Johns Hopkins Medicine developed a potential treatment for brain cancer that uses nanofibers embedded with a combination of drugs that work in concert to target tumors.

28 May 2026

Next-generation cancer therapy shows early promise as treatment candidate for glioblastoma

A next-generation cancer therapy being developed at McMaster University has shown early promise as a treatment candidate for glioblastoma, the most aggressive and most common type of primary brain cancer in adults.

13 May 2026

Testosterone may help limit brain tumor growth in men

In a new National Institutes of Health (NIH)-funded study, scientists at Cleveland Clinic discovered that hormones associated with male development may play a key role in limiting the growth of brain tumors in men.

6 May 2026

UIC researchers develop anti-cancer therapy inspired by bacteria in tumors

Researchers at the University of Illinois Chicago have developed an anti-cancer therapy inspired by bacteria found in cancer tumors.

28 Apr 2026

New molecule weakens glioblastoma and enhances immune response

A team of researchers from Brown University Health and Brown University has uncovered an important clue in the fight against glioblastoma, the most common and aggressive form of brain cancer in adults.

21 Apr 2026

Microglia actively shape glioblastoma growth and tumor spread

Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond the main tumor.

21 Apr 2026

Long-term exposure to air pollution (PM2.5) raises risk of developing cancer by 11 % and of dying from cancer by 12 %

The Union for International Cancer Control (UICC), with support from the Clean Air Fund, has released a global report, Clean air in cancer control: An overview of the evidence, presenting data on the scale of cancer risk and mortality from polluted air.

21 Apr 2026