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Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

In a new study, researchers assessed the efficacy of the scFv76 antibody against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung damage.

21 Sep 2022

Mechanism of action of different COVID-19 vaccines

In a recent study posted to the bioRxiv* preprint server, researchers at the University of Tuebingen and Imperial College London assessed humoral and cellular immune responses elicited by the recombinant adenoviral vector (rAdVV)- and messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines.

14 Sep 2022

How does SARS-CoV-2 affect the male genitourinary system?

In a recent paper published in the American Journal of Clinical and Experimental Urology, researchers reviewed existing data on the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male genitourinary (GU) tract.

7 Sep 2022

Study reveals serum proteomic signatures of long COVID patients

In a recent study posted to the bioRxiv*preprint server, researchers evaluated the serum proteomic signatures of long coronavirus disease (COVID) patients.

13 May 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

In a new study, researchers investigated whether the SARS-CoV-2 spike protein and its S2 subunit induced the expression of C–X–C motif chemokine 10, a subset of cytokine.

21 Mar 2022

Mapping the molecular gene signatures of respiratory viruses, including SARS-CoV-2

Researchers compare a large cohort of transcriptomic dataset maps of gene regulation by SARS-CoV-2 infection.

24 Oct 2021

Using saliva to predict COVID-19 severity in children

News-Medical speaks to Dr. Usha Sethuraman about her research into COVID-19 and how saliva could be used to help predict COVID-19 severity in children.

22 Oct 2021

Study aims to find ways of identifying children at risk for severe COVID-19

An ongoing study is looking at the relationship between cytokines in saliva and COVID-19 infection to help predict the severity of infection.

8 Oct 2021

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

A new study published on the bioRxiv* server describes the changes in the representation of a subset of activated monocytes in this group of patients.

23 Jun 2021

Maternal SARS-CoV-2 infection imprints immune response in the newborn

A new bioRxiv* preprint reports the immunological footprint in the newborn left by maternal infection with SARS-CoV-2 during pregnancy.

4 Jun 2021

A review of Traditional Chinese herbal medicine in management of COVID-19

Now researcher have summarized the experiences with the use of traditional Chinese herbal medicines for the management of COVID-19. Their study titled, “Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis,” was published in the January 2021 issue of the journal Phytomedicine.

24 Nov 2020

Immune systems of preemies can catch up

According to a new study published in March 2020 in the journal Nature Communications, babies born prematurely up to 32 weeks of pregnancy can quickly catch up on their immune system function after birth, bringing them to a state comparable to term infants.

9 Mar 2020

Scientists unravel immune cascade that drives tissue damage, complications in chlamydia infections

Closing a critical gap in knowledge, Harvard Medical School scientists have unraveled the immune cascade that fuels tissue damage and disease development in chlamydia infection - the most common sexually transmitted disease in the United States.

13 Feb 2018

Research finds how omega-3 supplements dampen harmful inflammatory reactions

OMEGA-3: Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health.

23 Aug 2017

New study suggests novel ways to treat serous retinal detachment

Wet age-related macular degeneration (AMD) is the leading cause of severe vision loss in older individuals. AMD and other serious chronic eye problems that affect younger individuals result when fluid accumulates abnormally under or within the retina. A new study published in The American Journal of Pathology shows for the first time that the release of substances from mast cells may be a causal factor in this type of eye pathology, and inhibitors of this release may offer new ways to treat serous retinal detachment.

22 Jul 2015

Assisted reproduction technology may increase risk of MS activity among women

Researchers in Argentina report that women with multiple sclerosis (MS) who undergo assisted reproduction technology (ART) infertility treatment are at risk for increased disease activity.

4 Oct 2012

New study reveals potential role of TGF-β1 in kidney disease

Fibrosis in the kidney is one of the key causes of progressive renal failure. High levels of the inflammatory molecule TGF-β1 in the kidney tubules due to tissue damage can cause fibrosis as well as nephron degeneration, resulting in loss of kidney function. To clarify the mechanisms regulating TGF-β1-mediated renal fibrosis, Koesters et al expressed high levels of TGF-β1 in renal tubules of mice. Nephron degeneration in this system was mediated by decomposition of the tubular cells. These data suggest that TGF-β1 may play a novel role in cell death of renal cells, thus contributing to renal fibrosis.

28 Jul 2010