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Study reveals why some women with deadly ovarian cancer respond better to treatment than others

New research is increasing our understanding about why some women with the most lethal form of ovarian cancer respond much better to treatment than others.

21 Jun 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

Research investigates whether the severity of SARS-CoV-2 infection can be predicted by analyzing the immunophenotype in the blood of cardiovascular disease (CVD) patients.

1 May 2023

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

30 Mar 2023

How does diet affect inflammation?

In a recent study published in the journal Nutrients, researchers in Italy suggest there is evidence that dietary factors may directly affect the immune system and play a role in chronic systemic inflammation.

26 Mar 2023

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

Researchers explore potential new target for cancer immunotherapy

A new study posted to the bioRxiv* preprint server, focused on the role of YAP in regulating MHC-I APM expression within tumor cells.

27 Feb 2023

Proteomics reveals a distinct IFN-driven plasma cytokine response to COVID-19 in infants and young children

Researchers assesses immune responses to SARS-CoV-2 shortly after birth using a multi-omics approach.

5 Feb 2023

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Researchers explored the relationship between the development of goblet inflammatory cells and the age-related pathophysiology of SARS-CoV-2.

19 Jan 2023

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Researchers at Memorial Sloan Kettering Cancer Center (MSKCC) in New York have discovered that common cancer treatments, such as radiotherapy or anthracycline drugs, cause long-term damage to heart tissue by activating a key inflammatory signaling pathway.

19 Dec 2022

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.

5 Dec 2022

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

CXCL10 News and Research

Study reveals why some women with deadly ovarian cancer respond better to treatment than others

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

How does diet affect inflammation?

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers explore potential new target for cancer immunotherapy

Proteomics reveals a distinct IFN-driven plasma cytokine response to COVID-19 in infants and young children

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Study suggests loss of smell and brain inflammation are independent in COVID-19

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

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