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Machine learning predicts who will decline faster in Alzheimer’s disease using routine clinic data

Researchers developed and validated ElasticNet machine learning models that predict 12-month MMSE and BADL outcomes in Alzheimer’s disease and mild cognitive impairment using routinely collected clinical data. The cognitive model demonstrated external validation in ADNI, showing that individualized progression forecasting is feasible without biomarkers or neuroimaging.

1 Mar 2026

New study refines the limits of brain mapping

When removing cancerous tissue in the brain, neurosurgeons often use "awake brain mapping" to minimize the risk of causing unintended disruptions to a patient's quality of life while removing as much tumor as possible. This practice, which has been used for decades, involves waking a patient up mid-surgery to test their neurocognitive functions in real time by stimulating the brain surface and assessing for functional changes.

26 Feb 2026

Nearly 6 in 10 women in the U.S. may have cardiovascular disease in the next 25 years

Driven by rising rates in high blood pressure, nearly 6 in 10 women in the U.S. will have some type of cardiovascular disease (CVD) in the next 25 years, according to a new scientific statement published today in Circulation, the peer-reviewed, flagship journal of the American Heart Association, a global force changing the future of health for all.

25 Feb 2026

Blood test models predict when Alzheimer’s symptoms may start years in advance

Researchers developed plasma p-tau217–based clock models that estimate when cognitively unimpaired individuals with Alzheimer’s pathology may develop symptomatic disease. The models predicted symptom onset within about three to four years and may help improve clinical trial selection while remaining unsuitable for individual clinical decisions at present.

22 Feb 2026

Loose clothing sensors enhance clinical movement tracking

Loose-fitting e-textiles may offer superior motion tracking capabilities, enhancing recognition accuracy and prediction over conventional rigid sensors.

19 Feb 2026

AI model accelerates antibody production and clone selection

As instigators of immunity, monoclonal antibodies are marvels of modern medicine, lab-made proteins that can treat cancers, autoimmune diseases, and many other conditions.

9 Feb 2026

Blood lipid–hormone ratios predict future asthma attacks years in advance

This study shows that specific ratios of circulating sphingolipids to steroids can predict the risk of future asthma exacerbations over five years with high discriminatory performance. By integrating metabolomics with longitudinal medical records, the research highlights lipid–hormone pathway imbalance as a key driver of asthma instability.

20 Jan 2026

New blood biomarker tracks brain injury progression after ischemic stroke

A new blood marker reflects the extent of brain injury after an ischemic stroke and can predict patient outcomes months to years later.

15 Jan 2026

New European initiative aims to transform real world Alzheimer’s disease care

Today, the ACCESS-AD consortium is announcing the launch of a transformative European initiative that will accelerate the implementation of scientific innovations for Alzheimer's disease (AD) management in real-world health systems.

13 Jan 2026

AI model can predict a person's disease risk using sleep data

A poor night's sleep portends a bleary-eyed next day, but it could also hint at diseases that will strike years down the road.

6 Jan 2026

Prenatal exposure to hot and humid conditions worsens child growth outcomes

The dangers of heat and humidity are so well known it's become cliche to mention them. But the impacts can extend farther than even scientists and doctors realized.

19 Dec 2025

New early-warning platform aims to bring dengue forecasting into real-world use

Thousands of dengue forecasting models have been published, but few have been tested in real public-health settings.

18 Dec 2025

MEA-driven graph modeling identifies early connectivity changes linked to autism

Multi-electrode arrays (MEAs) provide a noninvasive interface with sub-millisecond temporal resolution and long-term, multi-site recordings, enabling mechanistic investigations of in vitro human brain development and disease-related dysfunction; nevertheless, conventional MEA pipelines largely rely on firing/burst statistics or channel-/waveform-level features, which can be insufficient to systematically characterize and interpret network-level organization and its subtle pathological deviations.

16 Dec 2025

New model uses social media patterns to predict disease outbreaks

Vaccination rates are falling in many communities due to widespread misinformation and previously eliminated or controlled illnesses like measles are surging across the United States and Canada.

18 Nov 2025

Climate extremes continue to drive preventable deaths across the United States

Researchers led by investigators at Mass General Brigham have discovered that over the last 25 years, heat and cold-related deaths have caused more than 69,000 deaths in the U.S., disproportionately affecting certain populations. The findings are published in the Annals of Internal Medicine.

18 Nov 2025

FAU professor receives $746,998 to advance understanding of how the brain learns to see

Vision is one of the most fundamental senses, shaping how we perceive, navigate and interact with the world around us. Yet for more than 12 million Americans living with visual impairments, even small deficits can profoundly impact daily life, limiting independence and overall quality of life.

17 Nov 2025

Wild birds found to be key drivers of H5N1 outbreak in North America

Since late 2021, a panzootic, or "a pandemic in animals," of highly pathogenic bird flu variant H5N1 has devastated wild birds, agriculture, and mammals.

14 Nov 2025

Life expectancy gains are slowing

Research shows life expectancy growth is slowing, with significant implications for health policies and individual planning in high-income nations.

31 Oct 2025

New epimodulation approach improves outbreak forecasts

During an epidemic, some of the most critical questions for healthcare decision-makers are the hardest ones to answer: When will the epidemic peak, how many people will need treatment at once and how long will that peak level of demand for care last? Timely answers can help hospital administrators, community leaders and clinics decide how to deploy staff and other resources most effectively.

24 Oct 2025

Revolutionizing gait analysis with wearable sensors and 3D depth cameras

A study from the College of Engineering and Computer Science and the Sensing Institute (I-SENSE) at Florida Atlantic University reveals that foot-mounted wearable sensors and a 3D depth camera can accurately measure how people walk – even in busy clinical environments – offering a powerful and more accessible alternative to traditional gait assessment tools.

23 Oct 2025