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The Christie NHS Foundation Trust first to offer treatment in cancer patients’ homes

One of Europe’s largest cancer centres, The Christie NHS Foundation Trust, has become the first in the country to provide a treatment called Phesgo for breast cancer patients in their own homes. Phesgo is a combination of Herceptin

30 Apr 2021

New machine learning method for designing more effective antibody drugs

Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs.

15 Apr 2021

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells.

29 Jan 2021

SORLA protein promotes the growth of breast cancer brain metastasis

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells.

29 Jan 2021

Cancer Research UK announces dramatic cuts to its life-saving research budget

Cancer Research UK have announced today further dramatic cuts, slashing £45 million from its research budget.

10 Dec 2020

Researchers develop first report card on biosimilars for three blockbuster cancer drugs

Researchers have developed the first report card on biosimilars for three blockbuster cancer drugs marketed by Genentech/Roche: Rituxan, Avastin, and Herceptin.

2 Dec 2020

Targeted therapy may increase overall survival in patients with pancreatic cancer

Results from 46 patients given treatments that target specific molecular changes in tumor cells suggest that these therapies could help patients with pancreatic cancer whose tumors harbor those changes survive an extra year.

2 Mar 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with advanced HER2-positive breast cancer, with and without brain metastasis according to results of the HER2CLIMB clinical trial.

11 Dec 2019

New research shows significant gaps in deployment of 'coverage with evidence development'

Value in Health, the official journal of ISPOR- the professional society for health economics and outcomes research, announced today the publication of new research from The Netherlands showing important gaps in the deployment of "coverage with evidence development," a type of pharmaceutical managed entry agreement that gives patients access to treatments while additional evidence is being collected.

15 Jul 2019

Chemotherapy can wreak havoc on the heart

Cheryl Krafft was diagnosed with an aggressive form of non-Hodgkin's lymphoma and was put on a very high-powered chemotherapy regimen to rid her body of the cancer. What she was not counting on was the chemotherapy causing another equally deadly problem.

21 Jun 2019

Study uncovers new oncogenic function of receptor associated with Alzheimer's disease

Common and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease.

28 May 2019

Hundreds of new anti-cancer drug targets identified using CRISPR

A team of scientists from the Wellcome Sanger Institute have identified the genes that are essential for the survival of thirty types of cancer cells.

11 Apr 2019

Medication could mitigate side effects of chemotherapy for breast cancer patients

Researchers at the Stanford University School of Medicine have demonstrated a method of forecasting which breast cancer patients will suffer heart problems from a commonly used chemotherapy drug.

14 Mar 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Study shows precision medicines could aid more breast cancer patients via RNA-targeting

When women or men receive the worrisome diagnosis of breast cancer, that news comes with an important piece of information, namely, whether their cancer is HER2-positive or HER2-negative.

8 Feb 2019

Genetically modified chickens could soon lay eggs containing certain medications

In breakthrough research, a team of scientists from University of Edinburgh’s Roslin Institute, have genetically modified chicken to lay eggs that contain medications for arthritis and some cancers.

28 Jan 2019

Hens that lay human proteins in eggs offer cost-effective method of producing new drugs

Chickens that are genetically modified to produce human proteins in their eggs can offer a cost-effective method of producing certain types of drugs, research suggests.

28 Jan 2019

Researchers identify potential target for new breast cancer treatments

Researchers from the School of Basic & Medical Biosciences have identified a potential target that could lead to new treatments for triple negative breast cancer.

18 Dec 2018

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

An antibody that binds simultaneously to two distinct regions of the HER2 receptor to block the growth of cancer cells has shown promising signs of anti-tumor activity in a number of cancers including those of the gullet (esophagus), stomach and bowel.

14 Nov 2018