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Researchers examine morbidity linked to depressive disorders

Ross Baldessarini and an international group of investigators have analyzed the morbidity associated with depressive disorders in the current issue of Psychotherapy and Psychosomatics.

27 Apr 2017

Mayo Clinic investigators discover potential diagnostic markers for bipolar I disorder

Mayo Clinic researchers have discovered a series of proteins that could be diagnostic markers to identify bipolar I disorder. If this discovery sample can be validated through replication these markers may help as a diagnostic tool for psychiatrists treating mood disorders.

9 Dec 2015

Orexigen Therapeutics provides update on business and financial results for Q1 2015

Orexigen Therapeutics, Inc. today announced business and financial results for the first quarter ended March 31, 2015.

8 May 2015

Subthreshold mania signals impending bipolarity in children of bipolar patients

Subthreshold manic or hypomanic symptoms frequently precede clinical mood episodes in the children of patients with the condition, a study shows.

24 Mar 2015

Study shows strong link between subthreshold manic episodes and bipolar disorder in children

New research published today in the American Journal of Psychiatry indicates a strong link between subthreshold manic episodes and likelihood of developing bipolar disorder in children of parents with bipolar disorder. The study's findings could improve clinical assessment and care for these high-risk children by potentially enabling earlier identification, treatment or possible preventive measures.

3 Mar 2015

UC Berkeley study finds self-worth key to diagnoses of psychopathologies

Donald Trump's ego may be the size of his financial empire, but that doesn't mean he's the picture of mental health. The same can be said about the self-esteem of people who are living from paycheck to paycheck, or unemployed. New research from the University of California, Berkeley, underscores this mind-wallet connection.

8 Dec 2014

Bipolar mixed episodes increase significantly under DSM-5

Using the most recent diagnostic criteria increases the prevalence of mixed features in patients with bipolar disorder more than threefold, study findings indicate.

13 Nov 2014

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition.

11 Sep 2014

Bipolar II disorder course mapped in Japanese patients

The course of bipolar II disorder can follow several distinct trajectories, with a major depressive episode being the most common presenting feature, a study of Japanese patients suggests.

14 Aug 2014

Patients in new DSM-5 bipolar category ‘deserve attention’

People who fall into the DSM-5 Other Specified Bipolar and Related Disorders category carry a significant clinical burden, a study shows.

19 Jun 2014

Bipolar at-risk criteria identify ‘relevant clinical minority’

A set of ultra-high-risk criteria for bipolar disorder identifies a group of help-seeking patients with a high rate of new-onset mania or hypomania over the following year, say researchers.

19 May 2014

Smartphone app shows promise for detecting early signs of mood changes in people with bipolar disorder

A smartphone app that monitors subtle qualities of a person's voice during everyday phone conversations shows promise for detecting early signs of mood changes in people with bipolar disorder, a University of Michigan team reports.

8 May 2014

Electrode placement affects subthalamic nucleus stimulation outcomes

Researchers have identified factors associated with motor, cognitive and mood outcomes after deep-brain stimulation (DBS) of the subthalamic nucleus in a large cohort of patients with Parkinson’s disease.

4 Apr 2014

Diagnostic errors common among patients with bipolar disorder

Russian study data bolster the existing body of evidence showing that bipolar disorder is often misdiagnosed as depression.

5 Mar 2014

Comorbid OCD and bipolar disorder should be treated as mood disorder

Most patients with both bipolar disorder and obsessive–compulsive disorder should be treated as having bipolar disorder, researchers suggest.

21 Feb 2014

Bipolar disorder could be more common than thought

Bipolar disorder may be underdiagnosed in epidemiological surveys, say researchers who studied data from the World Mental Health surveys.

4 Feb 2014

Simple hypomania checklist detects bipolar II disorder

A 15-item hypomania checklist has shown potential for differentiating bipolar disorder, particularly type II, from major depressive disorder.

30 Jan 2014

Bipolar screening tools not tailored to young people

Current screening tools for bipolar disorder are poorly validated in the age group most at risk for developing the condition, say researchers.

9 Jan 2014

Conversion from psychotic depression to bipolar disorder explored

Danish researchers have identified a range of characteristics in people with psychotic depression that predict an increased risk for conversion to bipolar disorder.

21 Nov 2013