Immunoglobulin News and Research

RSS

Global collaboration can improve diagnosis and care for children with Kawasaki disease

International collaboration in research, diagnosis and care is critical to reducing the risk of serious heart conditions for children with Kawasaki disease worldwide, according to a new science advisory published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

18 May 2026

Slow and steady wins: Low-dose peanut immunotherapy safely desensitizes 82% of preschoolers in landmark trial

A Swedish randomized trial found that slow up-dosing peanut oral immunotherapy with a low maintenance dose helped 82% of preschool children achieve sustained peanut tolerance after three years. The approach proved safer than conventional protocols, with severe reactions uncommon and strong family adherence throughout treatment.

10 May 2026

Fucosylated IgG drives adipose tissue dysfunction during aging

A study published in Engineering has identified fucosylated immunoglobulin G (IgG) as a key mediator contributing to adipose tissue dysfunction during aging, offering insights into age-related metabolic disorders and potential therapeutic targets.

25 Apr 2026

Kenyan bat coronavirus uses human CEACAM6 to enter cells, raising spillover concerns

Researchers screened a phylogenetically diverse panel of alphacoronavirus spike proteins and found that a heart-nosed bat coronavirus from Kenya can use human CEACAM6 to enter cells.

23 Apr 2026

Study finds long COVID leaves a distinct immune signature in the blood

Researchers identified a small panel of inflammatory and neurology-related blood proteins that may help distinguish long COVID from recovery or no prior infection, while also showing that booster vaccination did not appear to worsen these protein responses in this cohort. The study also found that immune responses after reinfection differed from those seen after the first SARS-CoV-2 infection, suggesting altered long-term immune behavior in some previously infected individuals.

14 Apr 2026

SARS-CoV-2 rarely reaches first-trimester placentas but still disrupts early pregnancy immunity

Researchers analyzing 761 first-trimester pregnancies found that SARS-CoV-2 was rarely detected in placental tissues, suggesting in utero transmission early in pregnancy is uncommon. However, maternal infection was linked to immune dysregulation at the maternal-fetal interface, altered trophoblast signaling, and inflammatory changes that could affect placental development.

14 Apr 2026

Rat hepatitis E virus may be a hidden cause of hepatitis in humans

This Nature Communications review argues that rat hepatitis E virus is an emerging zoonotic cause of hepatitis that is likely underdiagnosed because current tests are limited and awareness remains low. It shows that ratHEV is widespread in urban rodent populations, can infect humans and some other animals, and may spread mainly through indirect environmental exposure rather than direct rodent contact.

12 Apr 2026

High affinity for immune receptors predicts antibody drug associated anaphylaxis risk

Antibody therapeutics are laboratory-made proteins designed to work like the body's natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including cancer cells or inflammatory molecules.

8 Apr 2026

CFHR1 could be a new diagnostic marker for IgA nephropathy

Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial cell proliferation, enhanced extracellular matrix production, and variable infiltration of inflammatory cells.

30 Mar 2026

Vitamin D may help shape how the immune system responds to gut bacteria in IBD patients

Vitamin D supplementation may help shape how the immune system responds to gut bacteria in people with inflammatory bowel disease (IBD), according to a Mayo Clinic–led study published in Cell Reports Medicine.

26 Mar 2026

New study maps global immune gene diversity across multiple populations

Inherited variations in antibody genes can affect how we respond to infections and vaccines, show two new studies from Karolinska Institutet in Sweden, published in the journal Immunity.

26 Mar 2026

Long COVID antibodies induce persistent pain-like symptoms in mice

A new study coordinated by researchers at UMC Utrecht and Amsterdam UMC shows that antibodies from Long COVID patients can induce persistent pain-like symptoms in mice.

24 Mar 2026

Families scramble to pay five-figure bills as clock ticks on promised preauthorization reforms

Sheldon Ekirch is used to being disappointed by her health insurance company.

13 Mar 2026

Study finds cockroach allergy often driven by shared proteins across arthropods

Researchers analyzed molecular sensitization patterns in Polish patients with perennial allergic rhinitis who tested positive for cockroach allergens. They found that most apparent cockroach allergies were driven by cross-reactive proteins shared with mites, seafood, and other arthropods rather than true cockroach-specific allergens.

13 Mar 2026

Japan's famous matcha could reduce sneezing in people with nasal allergies

There's now another reason to love Japan's famous matcha: a study in mice suggests that the green tea powder could reduce the need to sneeze in people with nasal allergies.

11 Mar 2026

Blood marker linked to Alzheimer’s also found in systemic amyloidosis

A certain blood protein regarded as an early indicator of Alzheimer's disease also appears to play a role in other disorders.

11 Mar 2026

Cultured beef shows mixed allergy risks in early food safety study

As cultured meat moves toward commercialization, people want to understand how it impacts health compared to conventional animal meat.

18 Feb 2026

Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

Intranasal boosting after prior intramuscular COVID vaccination induced strong mucosal IgA responses in a small human cohort. These antibodies showed markedly enhanced neutralising activity against Omicron variants and evidence of immune memory reprogramming toward mucosal protection.

15 Feb 2026

Top early-life factors driving childhood food allergy

This study analyzes 190 research papers to uncover early-life predictors of food allergies in children, highlighting skin barrier health and family history.

12 Feb 2026

New platform improves prediction of human antibody drug responses

An international research consortium, led by scientists at VIB and UGent, has developed a new platform that could change how antibody medicines are tested and brought to patients. The

1 Feb 2026