Interferons News and Research

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Discovery of unique brain cells sheds light on progressive multiple sclerosis

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease.

10 Oct 2025

Scientists identify key protein driving severe flu in older people

Scientists have discovered why older people are more likely to suffer severely from the flu, and can now use their findings to address this risk.

8 Sep 2025

Targeting ADAR1 offers new hope against glioblastoma

The most common and aggressive type of adult brain cancer, glioblastoma multiforme (GBM) is notoriously resistant to treatment, with a median survival of just 14 months following diagnosis.

5 Sep 2025

New study uncovers a surprising mechanism of resistance to immunotherapy

A new international study led by researchers at Moffitt Cancer Center, the Karolinska Institutet and the University of Texas MD Anderson Cancer Center has uncovered a surprising mechanism of resistance to immunotherapy: cancer's ability to injure nearby nerves.

21 Aug 2025

Respiratory viruses awaken dormant breast cancer cells and raise relapse risk

Respiratory viruses such as influenza and COVID-19 can reactivate dormant breast cancer cells in the lungs, raising the risk of metastasis. The process is driven by IL-6–induced cell changes and immune suppression, with the highest recurrence risk soon after infection.

14 Aug 2025

Researchers develop machine learning models to identify biomarkers for chronic fatigue syndrome

When cells expire, they leave behind an activity log of sorts: RNA expelled into blood plasma that reveal changes in gene expression, cellular signaling, tissue injury and other biological processes.

11 Aug 2025

New research links age-related gene changes to symptom decline

UCSF researchers have found that certain antiviral genes become less active over time in lupus, revealing why some patients see their symptoms fade as they age.

29 Jul 2025

Common plant virus shows powerful potential as cancer immunotherapy

A virus that typically infects black-eyed peas is showing great promise as a low-cost, potent cancer immunotherapy-and researchers are uncovering why.

28 Jul 2025

New RSV guideline aims to standardize pediatric care across China

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory infections (ALRTIs) in children under five and poses a persistent threat to child health worldwide.

20 Jun 2025

Study reveals how yellow fever vaccine triggers strong immune response

Researchers show how specific immune cells are activated by the vaccine - an important starting point for the development of new vaccines.

14 May 2025

Influenza virus hijacks human gene regulator to evade immune system

The influenza virus manipulates the body's gene regulation system to accelerate its own spread, according to researchers at the University of Gothenburg.

28 Apr 2025

Proteins linked to Parkinson's and ALS found to protect mitochondria

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria, small organelles, or subunits, within a cell that make and store energy and are found in almost all plants and animals.

8 Apr 2025

How your skin’s microbes shape immunity, inflammation, and chronic skin disease

Skin microbes do more than coexist—they shape immune responses, repair tissue, and influence gene expression across your lifespan. This review explains how disruptions in this microbiome-immune dialogue can lead to eczema, psoriasis, or acne.

2 Apr 2025

UZH researchers develop decoy molecules to restore immune defense

An immune system defect makes affected individuals vulnerable to severe viral diseases such as influenza or COVID-19. It is caused by the body's own antibodies, which inhibit important defense proteins known as type I interferons.

24 Mar 2025

Targeted inhibition of a 'signal jammer' protein may improve tumor response to immunotherapy

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein voltage-dependent anion channel 2 (VDAC2) like a signal jammer to prevent the body's anticancer systems from communicating with the immune system.

19 Mar 2025

Researchers move closer to a functional cure for chronic hepatitis B

Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

17 Mar 2025

The diverse immunological functions of megakaryocytes

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

17 Jan 2025

Protein CD74 could predict immunotherapy response in bowel cancer

Researchers at the Francis Crick Institute and Barts Cancer Institute, Queen Mary University of London, have shown that the amount of a protein called CD74 can indicate which people with bowel cancer may respond best to immunotherapy.

16 Jan 2025

Cellular RNA enhances MAVS signalosome activation in antiviral immunity

Scientists have uncovered a new role for a cell's own RNA in fending off attacks by RNA viruses. Some of the cell's RNA molecules, researchers found, help regulate antiviral signaling. These signals are part of the intricate coordination of immune responses against virus invasion.

19 Dec 2024

MS medications do not increase pregnancy risks, research shows

An analysis of over 3,700 pregnancies of women with multiple sclerosis indicates that the therapy doesn’t lead to increased risks of miscarriage, premature birth or serious birth defects.

18 Dec 2024