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Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

An Thought Leaders Invited Review published today in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual identity.

16 Dec 2025

Kids and teens go full throttle for e-bikes as federal oversight stalls

E-bike of Colorado sales manager Perry Fletcher said his sales and repair shop saw an increase in back-to-school sales to young riders and families this fall as the popularity of the battery-powered bicycles revs up.

24 Nov 2025

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline such as memory loss and behavioral disturbances that severely impair quality of life. Despite decades of research, effective disease-modifying therapies remain elusive, underscoring the urgent need for novel neuroprotective strategies.

19 Nov 2025

International experts urge the reclassification of postpartum psychosis to improve treatment

An international panel of leading women's mental health experts – including UVA Health's Jennifer Payne, MD – is calling to reclassify postpartum psychosis as its own category of mental illness to improve the care new mothers receive.

3 Nov 2025

Nasal spray of gold nanoparticles delivers lithium directly to the brain

In the form of a 'nasal spray', tiny gold particles act as carriers, delivering a treatment directly to the brain: developed by scientists at the Università Cattolica Rome campus/Fondazione Policlinico Universitario A. Gemelli IRCCS, a new nanotechnological device for the treatment and prevention of neuropsychiatric and neurodegenerative diseases.

8 Oct 2025

Ultra-processed foods affect sperm quality and metabolism even without extra calories

A controlled crossover trial in Cell Metabolism found that ultra-processed foods increase weight, fat mass, LDL:HDL cholesterol, and alter reproductive hormones in men, with some effects independent of calorie load. These diets also showed trends toward reduced sperm motility, shifts in pollutants, and transient inflammatory responses, highlighting risks beyond excess calories.

31 Aug 2025

Lithium deficiency emerges as a hidden driver of Alzheimer’s

What is the earliest spark that ignites the memory-robbing march of Alzheimer’s disease? Why do some people with Alzheimer’s-like changes in the brain never go on to develop dementia? These questions have bedeviled neuroscientists for decades.

8 Aug 2025

Scientists link brain lithium loss to early Alzheimer’s changes

Researchers have discovered that naturally occurring lithium in the brain is depleted early in Alzheimer’s disease, especially in the prefrontal cortex, and that restoring physiological levels with lithium orotate in mice can prevent brain damage and memory loss. The findings suggest lithium deficiency may be a modifiable risk factor for Alzheimer’s.

7 Aug 2025

Targeting lactate metabolism offers new avenues for cancer treatment

Lactic acid (LA) has transitioned from being perceived as a mere glycolytic waste product to a pivotal regulator of tumor-immune crosstalk.

5 Aug 2025

Study validates stem cell models for neurological diseases

In a comprehensive Genomic Press perspective (peer-reviewed review) article, an international team of neuroscientists has outlined crucial validity standards that could transform how researchers use stem cell technology to study devastating brain disorders.

15 Jul 2025

Shaping the future of psychiatry with precision medicine

In a comprehensive Genomic Press Interview published today in Genomic Psychiatry, Dr. Mirko Manchia opens up about his transformative journey from a small Sardinian city to becoming a leading voice in psychiatric pharmacogenomics, revealing how personal family experiences with mental illness sparked a lifelong quest to understand why psychiatric medications work brilliantly for some patients while failing others.

8 Jul 2025

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

A randomized clinical trial found that low-dose lithium aspartate did not improve cognitive dysfunction or fatigue in long COVID patients. Higher doses showed possible benefits in a small exploratory substudy, but larger trials are needed.

4 Jun 2025

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes therapies based on molecular profiles.

30 May 2025

Smart insoles offer real time gait tracking and early health warnings

A new smart insole system that monitors how people walk in real time could help users improve posture and provide early warnings for conditions from plantar fasciitis to Parkinson's disease.

17 Apr 2025

Lithium shifts circadian rhythms early in bipolar disorder and may offer clues to treatment response

A randomized controlled trial shows that lithium treatment in bipolar disorder patients reduces daytime activity, advances its onset time, and increases volatility in circadian rest-activity patterns. These changes appear early and independently of mood, offering promise as early biomarkers of treatment response.

14 Apr 2025

Lithium News and Research

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

Kids and teens go full throttle for e-bikes as federal oversight stalls

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

International experts urge the reclassification of postpartum psychosis to improve treatment

Nasal spray of gold nanoparticles delivers lithium directly to the brain

Ultra-processed foods affect sperm quality and metabolism even without extra calories

Lithium deficiency emerges as a hidden driver of Alzheimer’s

Scientists link brain lithium loss to early Alzheimer’s changes

Targeting lactate metabolism offers new avenues for cancer treatment

Study validates stem cell models for neurological diseases

Shaping the future of psychiatry with precision medicine

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Smart insoles offer real time gait tracking and early health warnings

Lithium shifts circadian rhythms early in bipolar disorder and may offer clues to treatment response

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

The brain-gut microbiota axis: Impact on mental health & potential treatment avenues

New system uses acoustic waves to separate tumor cells with precision

BEND lipids revolutionize mRNA delivery and gene-editing

Lithium shows promise as a potential therapy for autism spectrum disorder

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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