Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Scientists identify molecule driving one of the deadliest forms of breast cancer

Australian researchers have uncovered a promising new way to tackle one of the most aggressive forms of breast cancer, raising hopes for more effective treatments to stop the disease from spreading.

21 Aug 2026

Multi-organ chip uncovers key mechanisms behind cancer metastasis

Cancer spreading beyond the primary tumor – a process known as metastasis – is responsible for at least two-thirds of cancer deaths.

19 Aug 2026

Dual-action compounds show promise against aggressive cancer and infections

Cancer patients often face more than the disease itself. Their treatment is frequently complicated by infections and other health conditions, meaning they may need to take several different medications at once.

18 Aug 2026

Laser treatment may extend survival in glioblastoma patients

For patients facing a diagnosis of glioblastoma - one of the most aggressive and devastating forms of brain cancer - the standard path forward has long meant an invasive open-skull surgery and a daunting prognosis.

17 Aug 2026

Personalized T-cell therapy eliminates advanced kidney tumor in teenager

Researchers and physicians at the Hopp Children's Cancer Center Heidelberg (KiTZ) and other leading cancer centers report an exceptional treatment success in an adolescent with an advanced, therapy-resistant kidney tumor.

12 Aug 2026

AI-based methods help uncover hidden roots of tumor metastasis

A cancerous tumor is not a single enemy. It is made up of many different cell populations that can behave in very different ways.

12 Aug 2026

Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis

Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression, rendering it insensitive to conventional endocrine and targeted therapies.

12 Aug 2026

Genetic tool turns soft cancer cells into immune targets

Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a remarkable genetic tool that addresses one of the most persistent obstacles in cancer immunotherapy: the physical softness of tumors.

11 Aug 2026

Traditional prostate cancer features fail to predict hormone therapy benefit

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while traditional pathological features used to classify aggressive prostate cancer -such as high-grade disease, cancer extending outside the prostate and cancer involving the seminal vesicles- after surgery can help identify patients who are more likely to have worse outcomes, they do not predict who will benefit more from adding hormone therapy to postoperative radiation.

10 Aug 2026

Circular eccDNA shows potential to predict early-stage LUAD recurrence

LUAD is the most common histological subtype of lung cancer. Although surgery can be curative for patients diagnosed at an early stage, approximately 30%-50% develop recurrence or aggressive metastasis within five years.

10 Aug 2026

Integrated nanomaterials offer new strategies for cancer immunotherapy

Immune checkpoint inhibitors, cancer vaccines and cellular therapies have reshaped oncology, yet most patients still do not achieve lasting benefit.

9 Aug 2026

Thinning cancer cells' sugar coating could expose tumors to immune attack

Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat of sugar-derived molecules that throws the proverbial hounds of our immune systems off the scent.

7 Aug 2026

Two-gene interaction reveals metastatic risk in breast cancer

Why do some breast cancer patients face a much higher risk of distant metastasis, while others with seemingly similar disease experience far better outcomes?

7 Aug 2026

Piezo ion channels: Key regulators of digestive health and disease

Mechanosensitive Piezo ion channels, particularly Piezo1 and Piezo2, are gaining recognition as central regulators of digestive system physiology and disease.

7 Aug 2026

Tuft cell-like cancers exhibit unique biological characteristics across multiple organs

A growing body of evidence suggests that a rare epithelial cell type known as the tuft cell may play a far more significant role in cancer than previously recognized.

6 Aug 2026

Targetable MYH9 gene drives cancer progression and inherited genetic disorders

A comprehensive new review article highlights the growing importance of the MYH9 gene as a central player in both cancer biology and inherited genetic conditions, offering fresh perspectives on its potential as a therapeutic target.

6 Aug 2026

Study identifies a novel direct drug target for head and neck squamous cell carcinoma

Chemotherapy remains a cornerstone of treatment for head and neck cancers, the seventh-most common cancer type worldwide.

6 Aug 2026

Nerve-tumor interactions emerge as a transformative frontier in oncology

A new review article highlights a rapidly emerging frontier in oncology: the dynamic and influential relationship between nerves and tumors.

6 Aug 2026

Hidden microbes inside tumors reshape cancer immunity and treatment

A growing body of evidence is reshaping how cancer is understood, placing the spotlight on intra-tumoral microbiota as powerful yet previously overlooked players within the tumor microenvironment.

6 Aug 2026

Blocking ZFP36L2 protein may disrupt colorectal cancer metastatic growth

Digestion is hard on the cells that line the human gut, and they are constantly being shed and replaced. This renewal is driven by a population of tireless stem cells.

5 Aug 2026