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New AI model generates detailed maps of aging in brain regions

USC researchers have developed an approach that uses artificial intelligence to generate detailed maps that highlight differences in how distinct parts of the brain age.

3 Aug 2026

Persistent financial hardship tracks with poorer memory and processing speed by midlife

Researchers linked persistent low income and financial hardship across early and mid-adulthood to poorer processing speed and verbal memory at age 53 in a British birth cohort. Neuroimaging suggested greater vulnerability to later brain atrophy among men, people from disadvantaged childhood backgrounds, and APOE-ε4 carriers, although these subgroup findings require replication.

2 Aug 2026

UH psychologist receives NIH grant to evaluate remote parenting program for premature infants

A University of Houston psychologist has received a $2.8 million grant from the National Institute of Child Health and Human Development to lead the first randomized clinical trial testing whether a remotely delivered parenting program can improve healthy infant brain development to support long-term mental health outcomes for babies born prematurely.

29 Jul 2026

Blood tests improve Alzheimer's detection in Down syndrome patients

New blood tests that detect early changes associated with Alzheimer's disease are making diagnosis easier and accessible to more patients, since they are less invasive than the brain scans or spinal taps typically used for a definitive diagnosis.

27 Jul 2026

NIH grant funds study on stroke-related urinary incontinence

Urinary incontinence is a common but frequently overlooked consequence of stroke. Now, researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC and Rancho Los Amigos National Rehabilitation Center have received a grant from the National Institutes of Health to investigate the brain changes responsible for these symptoms and develop a more personalized approach to treatment.

27 Jul 2026

Longer activity bouts link to lower future dementia and mental health risks

A UK Biobank analysis of 66,483 adults found that longer daily moderate-to-vigorous activity bouts and less fragmented activity were associated with lower subsequent risks of inpatient diagnoses of dementia, depression, and anxiety, independent of total activity time. In neuroimaging data from 13,108 participants, these activity patterns were also associated with more favorable brain measures, although the observational analyses cannot establish cause and effect.

23 Jul 2026

Frequent TV watching links to higher white matter lesion volume

ARIC researchers linked self-reported TV watching and occupational sitting in midlife with brain MRI measures obtained roughly 24 years later in 1,712 adults without dementia. Frequent TV watching was associated with greater white matter hyperintensity volume and lower volumes in several brain regions, while sitting at work was associated with lower white matter hyperintensity volume and larger selected cortical volumes.

22 Jul 2026

Researchers identify risk factors for postoperative cerebral ischemia in patients with moyamoya disease

The buildup of fats, cholesterol, calcium, and immune cells within the blood vessel can lead to the narrowing or even complete blockage of the blood vessel.

20 Jul 2026

Fish oil supplementation during pregnancy changes two childhood brain metabolic markers

Randomized maternal fish oil supplementation from pregnancy week 24 lowered offspring cerebral blood flow and oxygen metabolism at age 10 but did not alter precuneus lactate. The small differences resembled a more adult-like metabolic profile, although researchers found no associated cognitive or behavioral benefits.

19 Jul 2026

Tau buildup in progressive supranuclear palsy alters brain networks linked to thinking and behavior

Researchers at Japan's National Institutes for Quantum Science and Technology (QST) have found that tau buildup in progressive supranuclear palsy (PSP) may affect brain networks involved in thinking and behavior.

17 Jul 2026

Biological markers reveal clinical vulnerability in abused children and adolescents

In children and adolescents who have experienced child abuse, the body appears to remain in a state of alert for too long, and this situation can affect several bodily systems, such as the neuroendocrine, immune and metabolic systems.

14 Jul 2026

Scientists trace severe irritability to the brain’s response to frustration

This review identifies maladaptive responses to frustrative non-reward as a potential mechanism underlying clinically significant irritability, particularly in youth. Animal studies reveal conserved behavioral responses, while human research links frustration to altered neural activity and highlights opportunities for cross-species treatment research.

10 Jul 2026

Early detection of congenital cerebral ventriculomegaly can help prevent developmental disabilities

Early detection and treatment of congenital cerebral ventriculomegaly (CCV)-when a fetus's fluid-filled brain ventricles swell due to a condition called hydrocephalus-can help clinicians prevent developmental or neurological disabilities in affected infants.

8 Jul 2026

New review shows why antidepressants often fail in Alzheimer’s and Parkinson’s depression

A Molecular Psychiatry review shows that depression in Alzheimer’s and Parkinson’s disease may reflect disease-specific molecular, neurotransmitter, inflammatory, and circuit-level disruptions rather than standard depression biology alone. It argues that broad antidepressants often show limited efficacy in these patients and that future trials should use biomarkers, neuroimaging, and symptom profiling to guide targeted treatments.

7 Jul 2026

Researchers identify brain circuits responsible for triggering OCD symptoms

Most of the time, the origin of obsessive-compulsive disorder (OCD) is unknown, but in some rare cases, it starts after a brain injury, such as a stroke or a tumor.

7 Jul 2026

New artificial intelligence model reveals invisible multiple sclerosis lesions

One of the uncomfortable truths about multiple sclerosis is that the part of the brain likely to reveal the most about the disease and how a patient will be impacted has been mostly invisible to clinicians.

7 Jul 2026

Study provides new insights into biological processes linked to Huntington’s disease

A study conducted by the Sant Pau Research Institute (IR Sant Pau) and Hospital de Sant Pau has identified for the first time in living individuals a brain pattern related to the tau protein that changes according to the stage of Huntington's disease.

6 Jul 2026

Sleep protects complex neural networks from drifting into states of permanent instability

Every animal that has ever been studied closely, from the fruit fly to the philosopher, surrenders each day to a state that looks, from the outside, like a small rehearsal for death.

1 Jul 2026

Blood metabolism maps how lifestyle tracks function in cognitive aging

A new study used pathway-level blood metabolomics to identify lifestyle-associated metabolic patterns linked to physical, cognitive, and daily functional performance across CN, MCI, and AD. The findings suggest that diet- and activity-linked pathway signals span energy, amino acid, lipid, inflammatory, oxidative stress, and microbiome-related metabolism, but require independent and longitudinal validation.

29 Jun 2026

Longer hormone exposure linked to healthier brain aging in women

Research indicates that hormonal therapies and later menopause are associated with increased brain volume and thickness, promoting healthier aging.

26 Jun 2026

Neuroimaging News and Research

New AI model generates detailed maps of aging in brain regions

Persistent financial hardship tracks with poorer memory and processing speed by midlife

UH psychologist receives NIH grant to evaluate remote parenting program for premature infants

Blood tests improve Alzheimer's detection in Down syndrome patients

NIH grant funds study on stroke-related urinary incontinence

Longer activity bouts link to lower future dementia and mental health risks

Frequent TV watching links to higher white matter lesion volume

Researchers identify risk factors for postoperative cerebral ischemia in patients with moyamoya disease

Fish oil supplementation during pregnancy changes two childhood brain metabolic markers

Tau buildup in progressive supranuclear palsy alters brain networks linked to thinking and behavior

Biological markers reveal clinical vulnerability in abused children and adolescents

Scientists trace severe irritability to the brain’s response to frustration

Early detection of congenital cerebral ventriculomegaly can help prevent developmental disabilities

New review shows why antidepressants often fail in Alzheimer’s and Parkinson’s depression

Researchers identify brain circuits responsible for triggering OCD symptoms

New artificial intelligence model reveals invisible multiple sclerosis lesions

Study provides new insights into biological processes linked to Huntington’s disease

Sleep protects complex neural networks from drifting into states of permanent instability

Blood metabolism maps how lifestyle tracks function in cognitive aging

Longer hormone exposure linked to healthier brain aging in women

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