Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Hyperactive cancer-promoting proteins help tumor cells evade immune attack

The immune system may recognize a cancer cell and still fail to destroy it. Researchers at Hiroshima University and their international collaborators found that hyperactive YAP and TAZ (YAP/TAZ), two cancer-promoting proteins, were associated with genomic instability that may make cancer cells more recognizable to the immune system, while also increasing PD-L2, which helps the cells suppress T-cell attack.

30 Oct 2026

Targeting specific enzyme reverses radiation-induced immune suppression in cancer

Researchers at the University of Chicago identified a mechanism to make immune cells reprogrammed by radiation therapy attack tumors rather than protect them.

30 Oct 2026

Tailoring prostate cancer radiotherapy to body clock could cut long-term side effects

A study by Leicester researchers shows that the timing of radiotherapy treatment may be as important as how it is given for prostate cancer patients.

30 Oct 2026

Platelet hyperactivity drives glioblastoma progression and deep vein thrombosis

New Cleveland Clinic research published in Cancer Cell shows that people with glioblastoma have more active platelets, which are cells involved in blood clotting. Platelets also communicate with other cells and can influence immune activity. The overactive platelets in people with glioblastoma slow the activity of cancer-fighting T cells, which can contribute to tumor growth and cancer progression.

30 Oct 2026

New study identifies potential targets for KRAS-related treatment resistance

Decoding of messenger RNA (mRNA) occurs during translation, the vital cellular process that builds proteins. Errors in this process are known to lead to cancer growth.

29 Oct 2026

New mechanism helps cancer cells selectively produce proteins that drive tumor growth

A previously unknown mechanism helps cancer cells selectively produce proteins that drive tumor growth - such as KRAS - in common cancers, according to new research from The University of Texas MD Anderson Cancer Center.

29 Oct 2026

Mutated neutrophils may trigger immune attacks in lupus

Scientists at La Jolla Institute for Immunology (LJI) and the University of Washington (UW) have discovered that patients with lupus have unusual mutations that may turn their bodies into battlegrounds.

28 Oct 2026

Narrow surgical margins may safely remove childhood soft tissue sarcomas

It's a question that surgeons often face: How much surrounding healthy tissue should they take out when removing a patient's cancer to be sure it is fully eliminated? Removing more can sacrifice nearby nerves, blood vessels, tendons and even joints, with lasting effects on quality of life.

28 Oct 2026

UCSF scientists develop smart CAR-T cells to fight childhood brain tumors

Scientists at UC San Francisco have engineered CAR-T cells that stay dormant until they reach the brain, where they switch on and destroy tumor cells.

28 Oct 2026

Targeted drug combination extends survival in advanced kidney cancer

Results of a phase 1/2 trial led by Roswell Park Comprehensive Cancer Center show that combining the targeted therapies bevacizumab (Avastin) and pazopanib (Votrient) significantly extends both progression-free and overall survival in patients with the most common type of kidney cancer.

28 Oct 2026

Overcoming cancer stigma requires policy changes and public education

Cancer-related discrimination arises from long-lasting cultural and institutional misconceptions, with significant impacts on every part of a person's quality of life and health – and Flinders University researchers say it requires coordinated policy, legal, institutional and public education responses for change to occur.

28 Oct 2026

Lab-on-a-chip technology helps predict childhood leukemia treatment responses

More than 120,000 people in the U.S. are living with acute lymphoblastic leukemia (ALL), and 6,000 new cases are diagnosed each year. Of those, more than 3,500 will be in children.

27 Oct 2026

Updated ASTRO guidelines recommend shorter radiation courses for prostate cancer

An updated clinical guideline from the American Society for Radiation Oncology (ASTRO) provides evidence-based recommendations on the use of hypofractionated radiation therapy for patients with localized prostate cancer.

27 Oct 2026

Endometrial cancer rates rise sharply among younger South Texas women

An Upper-South region of Texas including San Antonio and Bexar County had the state's highest hysterectomy-corrected incidence of endometrial cancer and the largest increase over time, a study led by scientists at The University of Texas at San Antonio Health Science Center and the National Cancer Institute showed.

27 Oct 2026

NCCN releases first-ever guide for cancer caregivers

Today, the National Comprehensive Cancer Network (NCCN)-an alliance of leading cancer centers in the United States responsible for guidelines that patients and providers rely on worldwide to improve outcomes-published its first-ever NCCN Guidelines for Patients focused specifically on how to support loved ones with cancer.

27 Oct 2026

Machine learning models predict common cancer risks using routine health data

Machine learning models using routinely collected health information, such as blood tests, medical history and lifestyle factors, could help identify people at higher risk of several common cancers, according to an international study reported at the ESMO Congress 2026.

27 Oct 2026

Patients with a form of advanced lung cancer lived 56 percent longer without their disease progressing after receiving radiotherapy in addition to standard treatment

Patients with an advanced form of lung cancer lived 56 percent longer without their disease progressing when radiotherapy was added to the standard of care whole-body therapy, including chemotherapy and/or immunotherapy, according to initial results from a clinical trial presented at the 2026 European Society for Medical Oncology (ESMO) Congress.

27 Oct 2026

Study establishes new perioperative standard in prostate cancer

An international phase 3 clinical trial that treated patients with high-risk localized and locally advanced prostate cancer with apalutamide - a next-generation neoadjuvant androgen-receptor pathway inhibitor (ARPI) - plus hormone therapy before and after prostate cancer surgery, was further validated by a substudy demonstrating a reduced risk of metastasis or death compared with standard of care.

27 Oct 2026

Cerebrospinal fluid liquid biopsy detects tumor DNA in complex brain cases

A Mayo Clinic study published in the Journal of Neuro-Oncology suggests that analyzing DNA in cerebrospinal fluid could provide another source of information when MRI cannot provide a clear brain tumor diagnosis or obtaining tissue through biopsy is difficult or potentially unsafe.

27 Oct 2026

Immunotherapy combination sets a new standard of care for extensive-stage small cell lung cancer

In patients with extensive-stage small cell lung cancer (ES-SCLC), tarlatamab, a bispecific T-cell engager, plus durvalumab as first-line maintenance therapy extended median overall survival by more than eight months, more than tripled progression-free survival, and reduced the risk of death by 58% compared to durvalumab alone, according to results of the phase 3 open-label, multicenter, randomized DeLLphi-305 study, which was presented by Jacob Sands, MD, Associate Chief of the Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute, during the Presidential Symposium at the European Society for Medical Oncology (ESMO) Congress 2026 in Madrid, Spain, on Oct. 24.

26 Oct 2026