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A study links a blood protein to memory and brain changes in Down syndrome

Researchers studying 88 adults with Down syndrome and 43 controls estimated that serum β-synuclein increased approximately two decades before expected Alzheimer’s symptoms, preceding changes in other blood biomarkers. Higher levels correlated with poorer memory and brain changes, but the cross-sectional study could not distinguish whether the earliest increase reflected Alzheimer’s-related synaptic dysfunction, trisomy 21-related neurobiology, or both.

11 Oct 2026

A trial of 3,220 smokers puts cash rewards for quitting to the test

In a randomized trial of 3,220 medically underserved adults referred for lung cancer screening, adding financial incentives to usual care and free medication increased sustained smoking abstinence at six months. Offering free medication alone did not significantly increase quit rates, and adding a forward-looking mobile tool did not improve outcomes beyond the incentives.

11 Oct 2026

$13.1 million grant backs bacterial therapies for resistant breast cancer

A scientist at Weill Cornell Medicine is working with colleagues at the University of Massachusetts Amherst on new, complementary research efforts engineering therapeutic Salmonella to target critical gaps in treatment for drug-resistant triple-negative breast cancers.

9 Oct 2026

Major global alliance invests billions to build predictive AI models of biology

Biohub, the U.S. Department of Energy, the National Institutes of Health, and new funding partners today announced a major expansion of an international effort to generate and make accessible the data enabling predictive AI models of biology.

7 Oct 2026

Childhood poverty increases risk of atherosclerosis in adulthood

People who grew up in low-income families are at greater risk of developing atherosclerosis in the coronary arteries later in life.

7 Oct 2026

$Longer spaceflight linked to increased hip fracture rates in astronauts$

Longer spaceflight linked to increased hip fracture rates in astronauts

New research has found that the rate of hip fractures in astronauts back on Earth was greater in the time period after an astronaut has been in space for more than 90 days than in the time period following shorter spaceflights or in non-astronauts.

1 Oct 2026

An AI-identified biomarker can look accurate and still fail its biggest test

The review examines how AI combines molecular, imaging, circulating, cellular, and digital data to identify potential disease biomarkers. Its authors argue that independent validation, biological testing, and evidence of better clinical decisions are needed before those candidates enter patient care.

28 Sep 2026

Tapping the power of cryo-ET to visualize how molecular machines interact inside cells

Scientists have often thought of cells as small bustling cities with parts that resemble factories, power grids, and shipping systems.

25 Sep 2026

AI tool provides early warning for organ failure in acute pancreatitis

Acute pancreatitis (AP) is one of the most common acute digestive disorders worldwide, and its most feared complication-persistent organ failure-drives mortality rates of 30% to 50%.

24 Sep 2026

Structural insights into synchronous calcium channel gating in muscle cells

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously.

24 Sep 2026

Novai publishes study supporting use of DARC imaging technology to identify patients at risk of central vision loss from macular atrophy

Novai. a medtech company combatting blindness and disability by pioneering early detection and intervention for eye and brain diseases, today announced the publication of a peer-reviewed study in Expert Review of Ophthalmology, which successfully demonstrates its ‘Detection of Apoptosing Retinal Cells’ (DARC) imaging technology as a promising biomarker for identifying patients at high risk of central vision loss caused by macular atrophy (MA).

23 Sep 2026

Simple prompts may improve cancer screening compliance among high-risk groups

People getting recommended screening tests for one cancer can be reminded about other relevant screenings. It's a simple way to increase compliance for potentially life-saving tests.

22 Sep 2026

New scanning method detects basal cell carcinoma early using AI

Researchers at FAU combine optical diagnosis method with AI-assisted image recognition.

22 Sep 2026

Engineered stone countertops linked to severe silicosis

The article describes a 47-year-old man who visited an emergency department for a minor injury to his lung and was found to have lung nodules after a computed tomography (CT) scan.

21 Sep 2026

Better fitness was linked to healthier brain structure, but not better memory

Researchers studying 353 cognitively unimpaired adults aged 60 to 94 found that higher muscular capacity was associated with lower basal ganglia perivascular space volume, while greater aerobic fitness was associated with greater gray matter volume and medial temporal lobe thickness. Fitness was not directly associated with global cognition or episodic memory, and evidence for cognitive reserve was limited, although VO₂max explained additional variation in delayed verbal memory beyond tau burden.

18 Sep 2026

Specialized imaging technique detects most clinically relevant prostate cancers

An elevated PSA level in the blood may indicate prostate cancer, but does not yet allow for a definitive diagnosis.

16 Sep 2026

Mobile LDCT lung cancer screening can reach vulnerable populations in resource-limited settings

Mobile low-dose computed tomography (LDCT) screening can reach high-risk and socially vulnerable populations in resource-limited settings, according to initial results from the Third Brazilian Early Lung Cancer Trial (BRELT3) presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC).

15 Sep 2026

Eye scans detect signs of atrial fibrillation years before diagnosis

People with atrial fibrillation have signs of the condition in the retinas of their eyes that can be detected as early as four years before diagnosis, finds a new study led by University College London (UCL) and Moorfields researchers.

14 Sep 2026

Scientists discover tiny protein region that shapes tooth enamel

Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years of wear.

11 Sep 2026

Study reveals structure of color-sensing cone cells in primates

For over 60 years, scientists have debated a basic structural question about cone photoreceptors, the cells that let vertebrates see color: are their light-sensing disk membranes closed off inside the cell, or are they open to the extracellular space? In non-mammalian species, the answer is clear - cone disk membranes typically stay continuous with the surrounding plasma membrane and are therefore open.

10 Sep 2026