Tranexamic Acid News and Research

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Landmark study in trauma care shines new light on tranexamic acid

A new study from Australia, New Zealand and Germany published in the New England Journal of Medicine raises important questions about the success or otherwise of emergency medicine.

14 Jun 2023

The clinical and virological characteristics of severe neonatal echovirus 11 infections

Researchers described severe and fatal infections in neonates caused by a new echovirus 11 (E-11) variant in France.

5 Jun 2023

Intramuscular injection of TXA may be a potential alternative to reduce obstetric bleeding

Intramuscular administration of tranexamic acid (TXA), a drug used to target severe bleeding after childbirth, is safe and quickly reaches therapeutic concentrations in pregnant women, according to a study involving researchers from the London School of Hygiene & Tropical Medicine.

6 Apr 2023

Study finds gender-based disparity in life-saving TXA treatment

Injured women are half as likely as men to receive the life-saving drug tranexamic acid (TXA) even though the treatment is equally effective regardless of sex, according to new research in the British Journal of Anaesthesia.

19 May 2022

At US hospitals, a drug mix-up is just a few keystrokes away

More than four years ago, Tennessee nurse RaDonda Vaught typed two letters into a hospital's computerized medication cabinet, selected the wrong drug from the search results, and gave a patient a fatal dose.

29 Apr 2022

TXA drug has minimal impact in controlling blood loss in severely injured trauma patients

A recent study found that the drug tranexamic acid has minimal impact in controlling blood loss in severely injured trauma patients at the standard doses given, according to researchers at Washington University School of Medicine in St. Louis.

21 Nov 2021

Oral TXA is equally efficacious at preventing blood loss in orthopedic surgery, interim study suggests

Interim results of a study conducted by researchers at Hospital for Special Surgery (HSS) suggest that oral tranexamic acid (TXA) is non-inferior to intravenous (IV) TXA in preventing blood loss in total knee and total hip replacement surgery.

14 May 2021

Trial examines prehospital administration of blood-clotting agent in severely injured trauma patients

Severely injured trauma patients who received a blood-clotting drug before arriving at the hospital had a better chance of surviving than those who didn't, according to new research from the University of Pittsburgh School of Medicine.

5 Oct 2020

Study shows why coronavirus is more dangerous in people with comorbidities

Why is the COVID-19 virus more dangerous in people with comorbidities?. Sadis Matalon, Ph.D., of the University of Alabama at Birmingham and colleagues in Texas and San Francisco asked that question in a hypothesis paper published online in Physiological Reviews on March 27.

3 Sep 2020

Antifibrinolytic agent could be a treatment for bleeding stroke

A common medication that reduces bleeding could be a treatment for bleeding stroke, particularly if administered quickly, according to late breaking science presented today at the American Stroke Association's International Stroke Conference 2020.

23 Feb 2020

Widely available drug could reduce deaths in traumatic brain injury patients, major study shows

A low cost and widely available drug could reduce deaths in traumatic brain injury patients by as much as 20%, depending on the severity of injury, according to a major study published in The Lancet.

15 Oct 2019

Using zebrafish to discover and identify new drugs to treat spinal cord lesions

A research team led by Leonor Saúde, Principal Investigator at Instituto de Medicina Molecular, in partnership with the company Technophage, SA, has designed a simple and efficient platform that uses zebrafish to discover and identify new drugs to treat spinal cord lesions.

22 Jul 2019

Blocking activity of plasma protein can be possible way to protect against radiation-induced injury

It is possible to prevent certain injuries that can occur in radiation therapy against cancer. By blocking the activity of a plasma protein during and immediately after radiation, the patient can be protected against injury. This is shown in a new doctoral thesis at Umeå University, Sweden.

20 Nov 2018

Blood management program associated with fewer transfusions in orthopedic patients

A patient blood management program designed to limit the amount of transfused blood orthopedic patients undergoing common surgeries such as hip and knee replacement receive was associated with fewer transfusions, reduced blood use and improved outcomes, reports a study published in the Online First edition of Anesthesiology, the peer-reviewed journal of the American Society of Anesthesiologists.

20 Aug 2018

Study: Drug used to treat blood loss may be beneficial for some stroke patients

Patients with stroke caused by bleeding on the brain may benefit from receiving a drug currently used to treat blood loss from major trauma and bleeding after childbirth, an international trial has revealed.

16 May 2018

Low-cost drug could prevent postpartum hemorrhage after vaginal delivery

Postpartum hemorrhage (major blood loss after labor and birth) is the leading cause of maternal mortality worldwide, accounting for approximately one-quarter of all maternal deaths.

29 Jan 2018

Low-cost drug for severe bleeding could save lives of mothers after childbirth

An inexpensive and widely available drug could save the lives of one in three mothers who would otherwise bleed to death after childbirth, according to a major study published in The Lancet. The global trial of 20,000 women found that death due to bleeding was reduced by 31% if the treatment was given within three hours.

29 Apr 2017

AAOS issues new guidelines for treatment of hip osteoarthritis

The American Academy of Orthopaedic Surgeons recently released a new clinical practice guideline on the treatment of osteoarthritis of the hip that strongly recommends the use of pre-surgical treatments to ease pain and improve mobility, including corticosteroid injections, physical therapy and non-narcotic medications.

11 Apr 2017

Simple saline solution could help alleviate chronic nosebleeds, study shows

Squirting a simple saline solution into the nose twice a day could alleviate chronic nosebleeds just as effectively as spraying with any one of three different medications, reports a study published online in the Journal of the American Medical Association on Sept. 6.

7 Sep 2016

Studies examine effectiveness of nasal sprays in reducing frequency, duration of HHT-related epistaxis

Two studies appearing in the September 6 issue of JAMA examine the effectiveness of nasal sprays to reduce the frequency and duration of nosebleeds caused by hereditary hemorrhagic telangiectasia (HHT), an inherited condition characterized by abnormal blood vessels which are delicate and prone to bleeding.

6 Sep 2016