Volvulus News and Research

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Volvulus, derived from the Latin term volvere, is a subtype of abnormal gastrointestinal (GI) rotation.

Researchers take major step towards developing vaccine for river blindness

The world's first vaccine for a disease that causes misery for millions in Africa could be tested within five years.

12 Jan 2016

Blackflies infected with Onchocerca volvulus parasite may spread nodding syndrome

Despite decades of research, scientists have yet to pinpoint the exact cause of nodding syndrome (NS), a disabling disease affecting African children. A new report suggests that blackflies infected with the parasite Onchocerca volvulus may be capable of passing on a secondary pathogen that is to blame for the spread of the disease. New research is presented in the International Journal of Infectious Diseases.

3 Oct 2014

Lindsley F. Kimball Research Institute receives grant for global health and development research project

The Lindsley F. Kimball Research Institute of the New York Blood Center announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

22 May 2013

TSRI receives fund to develop new field test for Onchocerciasis

Philanthropist, businessman and community leader John Moores has given The Scripps Research Institute approximately $2 million to fund the development of a new field test for Onchocerciasis, or river blindness, a parasitic infection that affects tens of millions of people in Africa, Latin America and other tropical regions.

21 Mar 2013

Teenagers with obesity can benefit from gastric bypass surgery just as much as adults

Teenagers with severe obesity can benefit from gastric bypass surgery just as much as adults. A study by Sahlgrenska Academy, University of Gothenburg, Sweden and Karolinska Institutet, Sweden found that 81 teenagers lost an average of 96.8 pounds following surgery, significantly improving their health and quality of life.

23 Oct 2012

CNN examines nodding disease among children in Northern Uganda

CNN examines nodding disease, a seizure disorder that has affected at least 3,000 children in Northern Uganda, as well as children in Liberia, Sudan, and Tanzania.

21 Mar 2012

Anacor, UCSF and NYBC collaborate to discover drug therapies for river blindness

Anacor Pharmaceuticals, the University of California San Francisco (UCSF) Sandler Center and the Lindsley F. Kimball Research Institute (LFKRI) of the New York Blood Center (NYBC) today announced the establishment of a research and development collaboration to discover new drug therapies for the treatment of river blindness (onchocerciasis), a parasitic disease that is the second leading cause of infectious blindness worldwide, and is most prevalent in Africa.

1 Dec 2010

Scientists develop first screening method to identify river blindness disease

Scientists from The Scripps Research Institute have developed the first screening method that rapidly identifies individuals with active river blindness, a parasitic disease that afflicts an estimated 37 million people. The test could change the current strategy of mass treatment in areas where river blindness, also known as onchocerciasis, is suspected.

7 Oct 2010

Six abstracts featuring FORE-SIGHT system presented at Pediatric Academic Societies meeting

CAS Medical Systems, Inc. today announced that six abstracts featuring the use of the FORE-SIGHT Absolute Oximeter were presented at the Pediatric Academic Societies meeting May 1-4 in Vancouver, BC, Canada. This meeting includes more than 7,500 leaders in academic pediatrics and is dedicated to the advancement of pediatric research and the advanced care of acutely ill children.

5 May 2010

Drug used to treat parasites in animals may offer new treatment for river blindness, study finds

"Closantel, an older drug used to treat a parasitic liver disease in animals, may prove effective at combating river blindness in humans, a major cause of infection-related blindness, U.S. researchers said on Monday," Reuters reports (Steenhuysen, 2/8).

10 Feb 2010

New research suggests closantel drug may be useful in combating river blindness

Scientists at The Scripps Research Institute have discovered a potential new use for the drug closantel, currently the standard treatment for sheep and cattle infected with liver fluke. The new research suggests that the drug may be useful in combating river blindness, a tropical disease that is the world's second leading infectious cause of blindness for humans.

10 Feb 2010

OEPA reports substantial reduction of river blindness in six endemic countries

A regional initiative launched in the 1990s to eliminate onchocerciasis (river blindness) in the Americas has substantially reduced the prevalence of the disease in recent years, as evidenced by a 31% decrease in the number of individuals requiring mass drug administration in six endemic countries. Results were reported today at the 58th annual meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).

23 Nov 2009

Onchocerciasis elimination feasible with ivermectin treatment

The first evidence that onchocerciasis elimination is feasible with ivermectin treatment was published in the open-access journal PLoS Neglected Tropical Diseases. Onchocerciasis is also called river blindness because the blackfly which transmits the disease breeds in rivers; it often blinds people, as well as causing debilitating skin disease. Over 37 million people are infected, often living in poor, rural African communities.

21 Jul 2009

Moxidectin being tested for onchocerciasis

A clinical trial is being launched in three African countries of a drug that could eliminate onchocerciasis, or river blindness, one of the leading infectious causes of blindness across Africa. The drug, moxidectin, is being investigated for its potential to kill or sterilize the adult worms of Onchocerca volvulus, which cause onchocerciasis.

1 Jul 2009

River blindness under control in Escuintla, Guatemala

An international team of researchers led by Rodrigo Gonzalez of the Universidad del Valle de Guatemala reports that the transmission of onchocerciasis or river blindness has been broken in Escuintla, Guatemala, one of the largest endemic areas in the Western Hemisphere to date to stop the transmission of the parasitic disease.

30 Mar 2009

CT useful and effective in diagnosis of patients with large bowel obstruction

The use of CT is highly effective in confirming large bowel obstruction and identifying the site and cause of obstruction, according to a recent study conducted by researchers at the University of South Manchester in Manchester, UK.

11 Apr 2008

Onchocerciasis parasite shows signs of resistance

Onchocerciasis is an infection caused by Onchocerca volvulus, a parasite nematode worm transmitted to humans by a species of black fly of the Simulium genus whose larvae develop in fast-flowing rivers.

31 Jan 2008

Neglected tropical diseases, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis and schistosomiasis

Though little known to most Americans, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis, schistosomiasis and other so-called neglected tropical diseases are responsible for severe health burdens, especially among the world's poorest people.

28 Dec 2007

Ivermectin is causing genetic selection in river blindness parasite

Ivermectin, the standard drug for treating river blindness (onchocerciasis), is causing genetic changes in the parasite that causes the disease, according to a new study by Roger Prichard (McGill University, Canada) and colleagues, published on August 30, 2007 in the open-access journal PLoS Neglected Tropical Diseases.

30 Aug 2007

Drug resistance of parasite which causes river blindness could lead to breakouts of the disease

Development of drug resistance in the parasite which causes river blindness could lead to breakouts of the disease in communities where it has been brought under control, conclude authors of an article in The Lancet.

17 Jun 2007