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Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

New clinical practice guideline addresses testing of molecular biomarkers in colorectal cancer patients

A new, evidenced-based clinical practice guideline on molecular biomarker testing for patients with colorectal cancer identifies opportunities for improving patient outcomes.

23 Feb 2017

Professor aims to develop shortcuts for targeted and effective cancer therapy

The aim is to identify precisely the one drug, or the correct combination of drugs, that are most effective against the specific tumor present in each patient. Professor hopes that new tools will come into use in the next five years.

13 Feb 2017

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

One of the most promising areas of cancer research is personalized therapy using precision medicine. The National Cancer Institute's NCI-MATCH is a large, ongoing clinical trial that matches tumors to therapies based on the tumor's genetic characteristics.

7 Feb 2017

Mobidiag announces CE-IVD marking of Amplidiag Easy that automates workflow from sample to results

Mobidiag Ltd, a Finnish molecular diagnostics company, today announced the CE-IVD marking of Amplidiag® Easy, a proprietary system allowing nucleic acid extraction and PCR setup directly from stool samples.

25 Jan 2017

Bruker is to be key International Phenome Centre Network corporate partner for NMR Technologies and SOPs

The International Phenome Centre Network (IPCN), founded by Imperial College London and more than a dozen international partners in Australia, Canada, China, Japan, Singapore, Taiwan, the US, and the UK (www.phenomenetwork.org), was launched officially this week at the 2016 World Innovation Summit for Health (WISH) conference in Doha, Qatar. This global network is a critical link between leading research centers across the world and will support research into some of today’s most pressing global health challenges.

From Bruker 23 Jan 2017

Mutations linked to endometrial cancer can be found in uterine lavage fluid before cancer diagnosis

Mutations that have been linked to endometrial cancer can be found in the uterine lavage fluid of pre- and post-menopausal women both with and without detectable cancer, according to a study published in PLOS Medicine by John Martignetti, MD, PhD of the Icahn School of Medicine at Mount Sinai and colleagues.

30 Dec 2016

AMP publishes joint guidelines for interpretation, reporting of sequence variants in cancer

The Association for Molecular Pathology (AMP), the premier global, non-profit molecular diagnostics professional society, today published guideline recommendations for both clinical laboratory professionals and oncologists that assess the status of next-generation sequencing (NGS)-based cancer tests and establish standardized classification, annotation, interpretation, and reporting conventions for somatic sequence variants.

17 Dec 2016

Childhood diarrhea from pathogens more common than previously thought?

The number of cases of childhood diarrhea, and its mortality toll of 500,000 per year, has not changed. Now, however, we can explain ~90% of the cases to specific pathogens. We can assign responsibility.

15 Dec 2016

PITX2 methylation biomarker shows promise for predicting prostate cancer recurrence risk

Prostate-specific antigen (PSA) and other biomarkers are essential tools for diagnosing and monitoring prostate cancer.

8 Dec 2016

Automated systems to aid microbiology departments launched by Beckman Coulter

Beckman Coulter has launched two automated systems in the UK to ease rapidly increasing workloads in microbiology and virology departments. The DxN VERIS Molecular Diagnostics system, for same-day molecular viral load testing, and the MicroScan Microbiology Systems for microorganism identification (ID) and antimicrobial susceptibility testing (AST), both rapidly and accurately identify therapeutic pathways for patient management.

From Beckman Coulter Diagnostics 29 Nov 2016

Highly antibiotic-resistant infections on the rise among U.S. children, study reports

Highly drug-resistant infections are on the rise among U.S. children, reports a new study published in the Journal of the Pediatric Infectious Diseases Society.

17 Nov 2016

Global effort may help win battle against antibiotic resistance

Antimicrobial resistance (AMR) does not seem to cause much worry among the general population and can be thought of as a future problem.

17 Nov 2016

Marker found on aggressive prostate cancer cells could help guide treatments, new research shows

RESEARCHERS have discovered that a marker found on aggressive prostate cancer cells could also be used as a way to guide treatments to the cancer, according to new research presented at the National Cancer Research Institute Cancer Conference in Liverpool.

9 Nov 2016

Myriad Genetics presents research data that validates accuracy of myPath Melanoma test

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced it will present two new studies at the American Society of Dermatopathology (ASDP) annual meeting being held Oct. 27-30, 2016 in Chicago, Ill.

31 Oct 2016

Renishaw launches unique healthcare facility at Miskin site in South Wales

Global precision engineering company Renishaw plc has announced a new Healthcare Centre of Excellence at its Miskin site, located close to Cardiff, South Wales.

From Renishaw plc - Spectroscopy 5 Oct 2016

Association for Molecular Pathology announces winners of 2016 awards

The Association for Molecular Pathology, the premier global, non-profit organization serving molecular diagnostics professionals, today announced the recipients of the Jeffrey A. Kant Leadership Award and the AMP Meritorious Service Award. Together with the AMP Award for Excellence in Molecular Diagnostics, these awards will be presented at the AMP 2016 Annual Meeting.

27 Sep 2016

New research shows childhood diarrhea cases significantly higher than estimated

The number of cases of childhood diarrhoea attributable to pathogens (bacteria, parasites, viruses or other infections) have been substantially underestimated and may be nearly twice as high as previous analysis suggests, according to new research published in The Lancet.

24 Sep 2016

NEJM publishes MINDACT trial results

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the peer-reviewed publication of the primary outcome results of the Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy (MINDACT) clinical trial in the prestigious New England Journal of Medicine (NEJM). (i, iii, iv) The publication demonstrates that 46% of breast cancer patients considered for chemotherapy, whose tumors are classified MammaPrint Low Risk, have excellent survival without chemotherapy, and can thus be candidates to avoid this toxic therapy.

29 Aug 2016

New NIST Standard Reference Material helps ensure accurate measurements of HER2 breast cancer gene

A new measurement standard developed by the National Institute of Standards of Technology has been used successfully by the Frederick National Laboratory for Cancer Research to check the performance of next-generation DNA-sequencing technologies for evaluating gene variations associated with an increased risk of breast cancer.

18 Aug 2016