Nasopharyngeal News and Research

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Host and in vitro genomic variability of SARS-CoV-2 and its variants

Researchers from the University of Sydney investigate the genomic variability of SARS-CoV-2 within the host and in vitro.

30 Nov 2021

An analysis of SARS-CoV-2 breakthrough infections by variant and vaccine

Researchers compared the distribution of SARS-CoV-2 genotypes to the prevalence of SARS-CoV-2 variants.

28 Nov 2021

Study finds no evidence to support favipiravir use in mild or asymptomatic COVID-19 patients

Researchers conducted a Phase II randomized placebo-controlled, double-blinded trial between July 8, 2020, and March 23. 2021.

28 Nov 2021

A review of natural immunity, vaccines, and variants in SARS-CoV-2 reinfection

In a literature review article published in the Journal of Community Hospital Internal Medicine Perspectives, authors from the US performed a thorough investigation of previous studies and case reports of SARS-CoV-2 reinfection. This review discusses the role of natural immunity, vaccines, and SARS-CoV-2 variants in reinfection.

25 Nov 2021

Using metal nanoparticles to fight SARS-CoV-2

A recent review article looks at the potential of nanotechnology in fighting severe acute respiratory syndrome 2 (SARS-CoV-2), with several possibilities of strategies in therapeutics, vaccines, and prevention.

25 Nov 2021

Serum SARS-CoV-2 antigen: A better predictor of COVID-19 severity

In this perspective, a new study published on the medRxiv* preprint server analyzed the clinical efficacy of two serum antigen tests to identify SARS CoV-2 infection and evaluate the kinetics of serum nucleocapsid (N) antigen in severe and non-severe patients for disease severity prediction.

24 Nov 2021

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Scientists have hypothesized that the number of immune cells and the amount of cytokines produced in response to SARS-CoV-2 infection in pregnant women change in accordance with the timing of maternal infection in pregnancy. This study is available on the bioRxiv* preprint server.

24 Nov 2021

A canine coronavirus zoonotic spillover and tropism shift

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21 Nov 2021

Severe COVID-19 patients have significantly higher NK and T cell frequency

A new study published in the open-access journal Cells aimed to clarify the role of NK and T cell subsets in SARS-CoV-2 infection in hospitalized COVID-19 patients to unravel their potential association with disease severity.

18 Nov 2021

REGEN-COV is effective in preventing severe COVID-19 in immunocompromised individuals

A recent study assesses the efficacy of repeat doses of REGEN-COV in SARS-CoV-2-negative adults who were healthy or had chronic medical conditions.

18 Nov 2021

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

A new study published in the journal Diagnostics was based on the hypothesis that detecting urinary SARS-CoV-2 nucleic acid––which may result in renal and cardiovascular endothelial destruction to facilitate viral access to the kidney parenchyma—may be used as a specific biomarker to indicate the severity of COVID-19.

16 Nov 2021

Diagnostic sensitivity, viral load and infectivity of SARS-CoV-2 in paired respiratory and oral samples

To understand the viral load in different sections of infected individuals, their respective shedding patterns, and the sensitivity of the SARS-CoV-2 assays, researchers published a study.

16 Nov 2021

Targeted proteomics for detection of SARS-CoV-2 proteins in clinical samples

A team of researchers from various institutions within the Netherlands examined the use of targeted MS-based proteomics for the detection of SARS-CoV-2 in research and clinical samples.

16 Nov 2021

Rapid thermal cycling approach for the detection of SARS-CoV-2

Researchers develop an ultrafast detection method for SARS-CoV-2 by direct RT-PCR without RNA extraction that is suitable for large-scale use.

15 Nov 2021

Promising results from Phase II REGEN-COV study

Initial results of the REGEN-COV Phase II study are presented.

15 Nov 2021

The case for vaccinating children under 12 against COVID-19

Researchers assess the need for coronavirus disease 2019 (COVID-19) vaccination in children who are 12 years of age or younger.

14 Nov 2021

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Researchers discuss a highly sensitive, specific, and rapid SARS-CoV-2 detection platform by coupling the RT-LAMP with glass nanopore sensors.

11 Nov 2021

Non-invasive breathing support to treat COVID-19 does not pose higher risk of infection

New research has found that the use of non-invasive breathing support to treat moderate to severe COVID-19 infection, isn’t linked to a heightened infection risk, as currently thought.

9 Nov 2021

Novel model-based framework evaluates immune mechanism of COVID-19 vaccine response

A model framework for characterizing viral dynamics and vaccine efficacy in non-human primates is described and applied to the identification of correlates of protection in three independent vaccine studies.

4 Nov 2021

Cas13 shines a light on SARS-CoV-2 variants

Now, a new study published on the medRxiv* preprint server describes and benchmarks SHINEv2, a Cas13-based nucleic acid diagnostic for SARS-CoV-2 detection. SHINEv2 combines temperature sample processing and lyophilized reagents to simplify the test procedure and assay distribution immensely.

4 Nov 2021