Peripheral Artery Disease News and Research

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Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.

Surgeons demonstrate potential genetic basis for varying outcomes of leg vein bypass surgery

Vascular Cures, a leading non-profit investing in research to develop breakthrough treatments for vascular disease, announced results that indicate there may be a genetic basis for the varying outcomes of bypass surgery in the legs.

20 Jun 2011

Patients still being enrolled in clinical trial for new peripheral vascular disease treatment

The first three patients to undergo an investigational surgical procedure for peripheral vascular disease that involves the patient's own stem cells continue to do well, reports the University of Louisville surgeon who is the principal investigator.

18 Jun 2011

HRT use linked to decreased risk of peripheral arterial disease in postmenopausal women

A new study presented at the 65th Vascular Annual Meeting of the Society of Vascular Surgery found that the use of HRT in postmenopausal women is associated with a significant reduction in the prevalence of peripheral arterial disease.

17 Jun 2011

Articles on health trajectories now available in Nursing Research journal

Health care research typically focuses on final outcomes such as cure or death—overlooking the fact that health and illness are dynamic states that evolve and change over time. A special collection of articles on health trajectory research is now available in a supplement to Nursing Research, official journal of the Eastern Nursing Research Society and the Western Institute of Nursing.

8 Jun 2011

Smoking increases woman's risk for peripheral artery disease 10-fold

A prospective study of initially healthy women aged 45 and over found that smoking is a potent risk factor for symptomatic peripheral artery disease, or PAD. PAD is a serious, often debilitating disorder, caused by narrowing of the arteries in the lower extremities. Symptoms of PAD include pain in the legs with normal activity and a feeling of tiredness in the leg muscles.

7 Jun 2011

FDA grants Pathway marketing clearance for JETSTREAM Navitus revascularization catheter for PVD

Pathway Medical Technologies, Inc, an innovator of endovascular treatments for peripheral vascular disease (PVD), announced today that the U.S. Food and Drug Administration (FDA) has granted the company 510(k) clearance to market JETSTREAM Navitus, an enhanced revascularization catheter for the treatment of PVD.

6 Jun 2011

IDEV completes enrollment in SUPERA stent trial for treatment of peripheral artery disease

IDEV Technologies, Inc. today announced the completion of enrollment in the SUPERB Trial, an FDA-approved IDE trial evaluating the use of IDEV's SUPERA stent system for treatment of peripheral artery disease in the superficial femoral artery.

3 Jun 2011

Twelve interventional live cases to use Toshiba's Infinix DP-i X-ray system at NCVH conference

Enabling physicians to perform a range of interventional procedures, Toshiba America Medical Systems, Inc.'s InfinixTM DP-i X-ray system provides clinicians with the ability to transition between cardiac and peripheral work seamlessly.

1 Jun 2011

Medtronic issues statement on results of CoreValve System clinical data presented at EuroPCR 2011

Medtronic, Inc. today issued a statement on results of clinical data presented at EuroPCR 2011 that show the Medtronic CoreValve System, delivered through a new approach beneath the collarbone, achieved excellent procedural success rates and low in-hospital complication rates.

From Medtronic 19 May 2011

USPTO issues notice of allowance to Vermillion's Peripheral Artery Disease biomarker patent

Vermillion, Inc., a molecular diagnostics company, today announced that the United States Patent and Trademark Office has issued a notice of allowance for a patent entitled "Panel of Biomarkers for Peripheral Artery Disease" to the company.

18 May 2011

MEDRAD's Cotavance catheter with Paccocath technology receives European CE Mark approval

MEDRAD, INC., a business of Bayer HealthCare, today announced it has received CE Mark for its Cotavance Paclitaxel Coated Balloon Angioplasty Catheter with Paccocath technology.

17 May 2011

Medtronic to present new clinical results on innovative medical devices at EuroPCR

New clinical data on a range of innovative medical devices from Medtronic, Inc., to treat cardiac and vascular diseases - from severe aortic stenosis and uncontrolled hypertension, to coronary and peripheral artery disease - will be presented next week at EuroPCR. Many of the presentations will be featured during late-breaking sessions at this large international interventional cardiology meeting, which takes place in Paris from May 17-20.

From Medtronic 12 May 2011

CHOP forms first startup firm to develop treatments for peripheral artery disease

Building on its extensive laboratory research using magnetically guided nanoparticles to deliver drugs to diseased blood vessels, The Children's Hospital of Philadelphia has just spun off its first startup company, Vascular Magnetics, Inc.

10 May 2011

Boston Scientific initiates clinical enrollment for INNOVA Self-Expanding Bare-Metal Stent System trial

Boston Scientific Corporation today announced the start of patient enrollment in the SuperNOVA clinical trial, an international, prospective, single-arm, non-randomized trial evaluating the safety and effectiveness of the INNOVA™ Self-Expanding Bare-Metal Stent System in patients with stenosis of the superficial femoral artery (SFA) or proximal popliteal artery (PPA).

6 Apr 2011

AngioScore launches AngioSculpt PTA Scoring Balloon Catheters for treatment of PAD

AngioScore, Inc., a developer of novel angioplasty catheters for use in the treatment of cardiovascular disease, today announced the launch of new, longer AngioSculpt PTA Scoring Balloon Catheters for the treatment of peripheral artery disease.

1 Apr 2011

Medtronic's Resolute drug-eluting stent pivotal U.S. data to be presented at ACC.11

Medtronic, Inc., today announced the imminent release of the pivotal U.S. data on its Resolute drug-eluting stent at ACC.11, the 60th Annual Scientific Session & Expo of the American College of Cardiology, which takes place April 2-5 in New Orleans.

29 Mar 2011

Pathway Medical initiates enrollment in JETSTREAM G3 Calcium Study in peripheral artery disease

Pathway Medical Technologies, Inc., an innovator of endovascular treatments for peripheral vascular disease (PVD), today announced enrollment of the first patient in the company's JETSTREAM G3 Calcium Study, a prospective, single-arm, multi-center registry to evaluate the treatment effects of the JETSTREAM G3 System in patients with moderate to severely calcified peripheral artery disease.

28 Mar 2011

New scientific statement gives guidance to doctors for treatment of blood clots

Doctors are encouraged to consider therapies in addition to blood thinners to treat certain patients with potentially dangerous blood clots that form in the deep veins and travel to the lungs, according to a new scientific statement from the American Heart Association.

22 Mar 2011

First clinical use of GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface on lower profile delivery system

W. L. Gore & Associates (Gore) today reported the first clinical use in the U.S. of the GORE® VIABAHN® Endoprosthesis with Heparin Bioactive Surface on a lower profile delivery system. The GORE VIABAHN Device is designed to percutaneously treat Superficial Femoral Artery (SFA) and iliac peripheral artery disease by relining the native vessel.

21 Mar 2011

Research roundup: Successful medical homes; shortage of HIV doctors; boosting use of $4 generic drugs

Every Friday, Jennifer Evans compiles this selection of recently-released health policy studies and briefs.

19 Mar 2011