Protein Synthesis News and Research

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MDI Biological Laboratory scientist sheds light on molecular mechanisms underlying aging

Scientists have known for decades that drastically restricting certain nutrients without causing malnutrition prolongs health and lifespan in a wide range of species, but the molecular mechanisms underlying this effect have remained a mystery.

17 Feb 2017

Research shows how cutting calories can slow aging process

There's a multi-billion-dollar industry devoted to products that fight signs of aging, but moisturizers only go skin deep. Aging occurs deeper -- at a cellular level -- and scientists have found that eating less can slow this cellular process.

13 Feb 2017

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Researchers have identified a gatekeeper protein that prevents pancreatic cancer cells from transitioning into a particularly aggressive cell type and also found therapies capable of thwarting those cells when the gatekeeper is depleted.

9 Feb 2017

Research finding provides new target for regulating cell division

Modern genome sequencing methods used to measure the efficiency of synthesis of individual protein during cell division has found that the enzymes that make lipids and membranes were synthesized at much greater efficiency when a cell is ready to split.

19 Jan 2017

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.

18 Jan 2017

Study provides insights into CPEB4 gene and fatty liver disease

This condition generally leads to chronic inflammation (non-alcoholic steatohepatitis), which can trigger fibrosis, cirrhosis and ultimately liver cancer. This study on the basic biology of the liver paves the way to examine therapeutic strategies to fight and prevent fatty liver disease.

18 Jan 2017

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of research, understanding why cancer cells become invasive has remained shrouded in mystery.

17 Jan 2017

Surveillance machinery in cells recognizes and destroys defective genetic material, research shows

New research out of Case Western Reserve University School of Medicine describes a mechanism by which an essential quality control system in cells identifies and destroys faulty genetic material. The findings were published online December 23 in Nature Communications.

11 Jan 2017

Scientists find new treatment option for rare autoimmune disease

Anti-NMDA receptor encephalitis is an inflammatory disease that affects the central nervous system.

6 Jan 2017

Researchers develop new microfluidic device to study brain inflammation

The blood-brain barrier is a network of specialized cells that surrounds the arteries and veins within the brain. It forms a unique gateway that both provides brain cells with the nutrients they require and protects them from potentially harmful compounds.

6 Dec 2016

Scientists discover ribosomal protein-based cancer signature

A research team at the University of Basel's Biozentrum has investigated the expression of ribosomal proteins in a wide range of human tissues including tumors and discovered a cancer type specific signature.

6 Dec 2016

Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists from the Lomonosov Moscow State University in cooperation with colleagues have worked out a safe, not that expensive and highly efficient method, which allows to speed up and improve searching of new germicides.

29 Nov 2016

TSRI scientists discover sub-region in the brain that works to form contextual fear memory

While the romantic poets' idea of memories being akin to spirits may have poetic merit, the scientists' perspective is that memories are concrete, physical entities that can be visualized within various regions of the brain.

14 Nov 2016

Two widely prescribed antibiotics may combat bacteria differently than previously thought

Two widely prescribed antibiotics -- chloramphenicol and linezolid -- may fight bacteria in a different way from what scientists and doctors thought for years, University of Illinois at Chicago researchers have found.

2 Nov 2016

Scientists find how selenium gets integrated into protein molecules

Humans need eight essential trace elements for good health, and one of them is selenium - a powerful antioxidant that is important for thyroid and brain function as well as metabolism.

6 Oct 2016

Novel technique offers new insights into growth variation across single cells

A new technique invented at MIT can precisely measure the growth of many individual cells simultaneously.

5 Sep 2016

New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

One of the greatest medical accomplishments of the past century was the introduction of antibiotics into the clinic.

18 Aug 2016

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation-induced bone marrow failure.

11 Aug 2016

Researchers uncover new preventative way to battle against Ascaris roundworm infection

Scientists working out of Trinity College Dublin, Maynooth University, and Queen Mary University of London have unearthed a potential new preventative option to combat Ascaris roundworm infection.

8 Aug 2016

Researchers show how p53 protein can control gene expression at levels of transcription, mRNA translation

Proteins that bind DNA or RNA are usually put in different categories, but researchers at Umea University in Sweden and Inserm in France recently showed how the p53 protein has the capacity to bind both and how this controls gene expression on the levels of both transcription (RNA synthesis) and mRNA translation (protein synthesis).

7 Aug 2016