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Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and kidney function, comorbid medical problems and polypharmacy (the simultaneous use of multiple drugs to treat medical conditions).

28 Jun 2022

Simple scan can reveal if people are at increased risk of late-life dementia

Late-life dementia is becoming increasingly common in people after 80 years of age.

27 Jun 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

AbbVie today announced the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended the approval of upadacitinib (RINVOQ® 15 mg, once daily) for the treatment of active non-radiographic axial spondyloarthritis (nr‑axSpA) in adult patients with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI), who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).*

27 Jun 2022

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

A new study reported four cases of Myelin Oligodendrocyte Glycoprotein-Associated Disorder that commenced after SARS-CoV-2 infection.

21 Jun 2022

Spinal posture assessment in health exams reliably detects cognitive decline

A mass survey of citizens aged 50 to 89 years examined whether cognitive decline could be detected by sagittal spinal balance measurement based on a radiological approach.

10 Jun 2022

Long wait for justice: People in jail face delays for mental health care before they can stand trial

Beau Hampton’s long wait for psychiatric treatment began last year, after he was accused of attacking his foster father and charged with a misdemeanor.

10 Jun 2022

$Study: Male smokers are at increased risk of osteoporosis, bone fractures, and early death$

Study: Male smokers are at increased risk of osteoporosis, bone fractures, and early death

It's no secret that puffing cigarettes is the culprit behind a whole host of ailments, including respiratory diseases and cancers of the lungs and throat.

8 Jun 2022

Newly developed hydrogel proven effective in relieving chronic low back pain

An experimental formulation of a hydrogel, injected into spinal discs, proved safe and effective in substantially relieving chronic low back pain caused by degenerative disc disease (DDD), according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting, in Boston.

8 Jun 2022

New injectable therapy helps repair spinal cord injuries with dancing molecules

A new injectable therapy for spinal cord injuries uses specially engineered molecules that trigger a healing response in spinal cells.

7 Jun 2022

Exploring the effectiveness of various treatments in people with axial spondyloarthritis

axSpA is a chronic inflammatory rheumatic disease that mainly affects the spine and sacroiliac joints. It can cause significant pain and disability.

3 Jun 2022

Despite a first-ever ‘right-to-repair’ law, there’s no easy fix for wheelchair users

Robin Bolduc isn't the type of person who takes "no" for an answer — particularly when it comes to fixing her husband's wheelchair.

2 Jun 2022

Children from historically marginalized groups or poor backgrounds less likely to survive neuroblastoma

Children with high-risk neuroblastoma had worse outcomes if they were from certain racial/ethnic groups or were on public rather than private insurance, despite being treated in clinical trials with standardized protocols, according to a study led by investigators from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

26 May 2022

NIH team documents various types of neuropathy after COVID vaccination

In a recent study posted to the medRxiv* preprint server, researchers investigated if coronavirus disease 2019 (COVID-19) vaccination could result in neuropathic symptoms.

19 May 2022

New methods can make spinal cord less excitable and could be used to treat muscle spasms

Poor sleep, difficulty moving and injuries from hitting something accidentally are just some of the challenges faced by suffers of often-painful involuntary muscle spasms.

11 May 2022

$Women with obesity and overweight found to be more susceptible to fractures$

Women with obesity and overweight found to be more susceptible to fractures

New research being presented at the European Congress on Obesity (ECO) in Maastricht, the Netherlands (4-7 May), has found that women with obesity and overweight, particularly women with high waist circumference, are more susceptible to fractures than those with normal weight.

8 May 2022

$Using AI to predict how cancer may affect the probability of spinal fractures$

Using AI to predict how cancer may affect the probability of spinal fractures

As medicine continues to embrace machine learning, a new study suggests how scientists may use artificial intelligence to predict how cancer may affect the probability of fractures along the spinal column.

5 May 2022

Understanding dysphagia symptoms after spine surgery can help improve patients' quality of life

Difficulty swallowing is one of the most common complications of anterior cervical spine surgery (ACSS).

3 May 2022

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

28 Apr 2022

Researchers create 3D in vitro model that reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.