Whole Genome Sequencing News and Research

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Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

In a recent study posted to the medRxiv* preprint server, researchers in Canada assessed the effectiveness of protection elicited by the fourth dose of the coronavirus disease 2019 (COVID-19) mRNA vaccine.

4 Oct 2022

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

In a new study, researchers compared the transmissibility of novel and emerging SARS-CoV-2 variants.

29 Sep 2022

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Researchers explored the SARS-CoV-2 genome using high-throughput genome sequencing to provide novel insights into how the novel SARS-CoV-2 Omicron BA.2.3.7 variant enters and spreads among the otherwise naïve Taiwanese population.

29 Sep 2022

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Researchers explored SARS-CoV-2 variants of concern/interest (VOC/VOI) kinetics and variations among non-hospitalized acute COVID-19 patients.

29 Sep 2022

How do clinical outcomes in patients infected with different Omicron subvariants differ?

Researchers compare the clinical outcomes, upper respiratory viral loads, and viral recovery of different SARS-CoV-2 Omicron subvariants on cell cultures.

27 Sep 2022

Differences in protection from previous infection or vaccination against infection with Omicron BA.4/5 or BA.2

Researchers investigated the differences in vaccination- and previous infection-induced immunities against the Omicron BA.2 and BA.4/5 subvariants of SARS-CoV-2.

27 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

How frequent was SARS-CoV-2 and malaria co-infection during the first wave of the pandemic?

Researchers determined the prevalence of circulating SARS-CoV-2 variants and the frequency of co-occurrence of COVID-19 and malaria in Burkina Faso, West Africa.

22 Sep 2022

Environmental surveillance detects poliovirus type 2 outbreaks in Israel

The wastewater environmental surveillance conducted in Jerusalem, Israel, has detected an increasing population of poliovirus type 2. Furthermore, these viral isolates are associated with vaccine-derived viral strains.

19 Sep 2022

Soy protein diet increases susceptibility to Clostridioides difficile infection

According to a recent study published in the journal Cell Reports, a diet rich in soy protein increases human Clostridioides difficile susceptibility by increasing the gut amino acids (AAs) levels and promoting the growth of Lactobacillus.

18 Sep 2022

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

In a recent study posted to the medRxiv* preprint server, researchers in Australia determined whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta-ORF7aΔ17del [open reading frame 7a protein with 17-nucleotide (nt) frameshift-inducing deletion] variant has a fitness advantage over the Delta variant lacking the ORF7aΔ17del deletion (Delta-ORF7aintact) and/or the SARS-CoV-2 lineage (A.2.2).

12 Sep 2022

Individual COVID-19 infections include multiple variants of the SARS-CoV-2 virus, research shows

Researchers at Case Western Reserve University found wide genetic variation in SARS-CoV-2 viruses among 360 patients whose viral infections were genetically sequenced, showing that all individual infections include multiple variants of the virus.

9 Sep 2022

Scientists identify genetic variants linked to an increased risk of developing Hodgkin lymphoma

Why did my child get cancer? Clinicians have longed for a way to help answer this question. Doctors knew Hodgkin lymphoma sometimes occurs in families, but why this happens has been a mystery. Scientists at St. Jude Children's Research Hospital have now helped solve it.

9 Sep 2022

The associations between vaccination status, type, and time since vaccination with lineage identity during the emergence of new SARS-CoV-2 variants

Researchers assessed the association between SARS-CoV-2 strains and patient age, COVID-19 vaccination status, vaccine type, and days elapsed since the most recent vaccination among New York residents.

7 Sep 2022

The prevalence, genetic diversity, and evolution of SARS-CoV-2 in white-tailed deer in New York

Researchers investigated the prevalence, genomic diversity, and evolution of SARS-CoV-2 among white-tailed deers in New York.

6 Sep 2022

CDC releases investigation notice regarding outbreak of E. coli O157 infections in Michigan and Ohio

A CDC investigation notice regarding a multistate outbreak of E. coli O157 infections is now live: https://www.cdc.gov/ecoli/2022/o157h7-08-22/index.html

22 Aug 2022

SARS-CoV-2 variant neutralization and novel mAbs reveal protection against Omicron in new research

Researchers assessed the SARS-CoV-2 variants of concern (VOCs) transmission dynamics and neutralization by vaccine-induced antibodies and monoclonal antibodies (mAbs).

19 Aug 2022

Researchers develop a novel method to screen publicly available raw WGS data of SARS-CoV-2

Researchers developed a novel method to screen publically available raw whole genome sequencing data of SARS-CoV-2 and identify mutations of interest more rapidly.

18 Aug 2022

Genomic surveillance highlights the challenges posed by "shapeshifting" strains

A pioneering genomic surveillance study has provided the clearest picture yet of the arms race between Streptococcus pneumoniae, the bacterium responsible for a range of illnesses such as pneumonia and meningitis, and the vaccines designed to protect against the most dominant types. A strain called GPSC10 was found to be a particular threat, due to its increased virulence, ability to transform its structure to evade vaccines and its resistance to several common antibiotics.

17 Aug 2022

Verogen and Gene by Gene Form Groundbreaking Partnership to Accelerate Adoption of Forensic Investigative Genetic Genealogy

Verogen, Inc. and Gene by Gene today announced a partnership to accelerate the adoption of forensic investigative genetic genealogy.

From Verogen, Inc. 16 Aug 2022

Whole Genome Sequencing News and Research

Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

How do clinical outcomes in patients infected with different Omicron subvariants differ?

Differences in protection from previous infection or vaccination against infection with Omicron BA.4/5 or BA.2

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

How frequent was SARS-CoV-2 and malaria co-infection during the first wave of the pandemic?

Environmental surveillance detects poliovirus type 2 outbreaks in Israel

Soy protein diet increases susceptibility to Clostridioides difficile infection

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

Individual COVID-19 infections include multiple variants of the SARS-CoV-2 virus, research shows

Scientists identify genetic variants linked to an increased risk of developing Hodgkin lymphoma

The associations between vaccination status, type, and time since vaccination with lineage identity during the emergence of new SARS-CoV-2 variants

The prevalence, genetic diversity, and evolution of SARS-CoV-2 in white-tailed deer in New York

CDC releases investigation notice regarding outbreak of E. coli O157 infections in Michigan and Ohio

SARS-CoV-2 variant neutralization and novel mAbs reveal protection against Omicron in new research

Researchers develop a novel method to screen publicly available raw WGS data of SARS-CoV-2

Genomic surveillance highlights the challenges posed by "shapeshifting" strains

Verogen and Gene by Gene Form Groundbreaking Partnership to Accelerate Adoption of Forensic Investigative Genetic Genealogy

The art of CRISPR: The power and promise of gene editing eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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