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$CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory$

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

A two-year, multi-center clinical study with 167 patients with class III-IV refractory angina randomized to low and high dose CD34+ cells or placebo has revealed that patients who received either a high or low dose of CD34 -- a member of a family of proteins that have an impact on vascular-associated tissue -- cells had a significant reduction in angina frequency over patients who received placebo.

2 Jun 2016

Oncologists combine two different types of immunotherapy to successfully treat metastatic melanoma

Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues describe their approach in a paper, "Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient," that will be published online May 30 in The Journal of Experimental Medicine.

30 May 2016

UTHealth's Mobile Stroke Unit fights stroke through research, technology and patient care

About 800,000 strokes occur in America each year; that's about one every 40 seconds. Houston resident Joe Carrabba experienced one of them.

28 May 2016

Study explores history of penumbra in untreated acute stroke patients

Radiological imaging is being used more often to evaluate stroke diagnosis and outcomes, with penumbra, or tissue that is at risk of progressing to dead tissue but is still salvageable if blood flow is returned, as a potential target for therapy.

26 May 2016

Study explores differences in neuroimaging utilization for stroke from population perspective

A person is admitted to the hospital with a stroke, but not much is known about whether or not that patient will undergo neuroimaging.

26 May 2016

New, screen-printed, flexible MRI coils could lead to shorter scan time periods

New, screen-printed, flexible MRI coils may be able to reduce the amount of time it takes to get an MRI scan.

26 May 2016

CGT, CTM CRC collaborate to test patented scaffold technology for commercial scale cell expansion systems

The Cell and Gene Therapy Catapult and the CRC for Cell Therapy Manufacturing, the Australian centre for translation of cell therapy technologies, today announce a project to test at scale CTM CRC’s patented scaffold technology.

26 May 2016

Clinical study supports safety, efficacy of GI Windows’ IAS as treatment option for Type 2 diabetes

GI Windows, Inc., a clinical-stage medical device company, today announced the presentation of six-month results of the first-ever clinical study evaluating the endoscopic creation of a dual-path enteral diversion using the company’s Incision-less Anastomosis System (IAS) at Digestive Disease Week® 2016 (DDW), in San Diego, Calif.

26 May 2016

ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

Initiating antiretroviral therapy (ART) soon after diagnosis of an HIV infection did not prevent the progression of significant arterial inflammation in a small group of previously untreated patients.

26 May 2016

Early diagnosis of lung cancer can increase survival rate by 73%

The UK Lung cancer screening trial (UKLS) has been successfully completed and demonstrated that patients with a high risk of developing lung cancer can be identified with early stage disease and have up to a 73% chance of surviving for five years or more. The UKLS trial was conducted by experts in the University of Liverpool.

25 May 2016

Multimodal therapy may improve survival of pancreatic cancer patients

In roughly one-third of pancreatic cancer patients, tumors have grown around the pancreas to encompass critical blood vessels. Conventional wisdom has long held that surgery to remove the tumors is rarely an option, and life expectancies are usually measured in months.

25 May 2016

Radiation-immunotherapy combination can help treat melanoma

Combining radiation treatments with a new generation of immunotherapies is showing promise as a one-two-punch against melanoma, Loyola Medicine researchers report in a review article.

20 May 2016

Simple sarcopenia screening method could easily diagnose severity of heart disease

Researchers from Kumamoto University in Japan have shown that a simple screening method could quickly and easily diagnose the severity of heart disease. The method was originally developed to diagnose sarcopenia, a disease that causes a loss of muscle mass and strength.

19 May 2016

Mazor Robotics signs strategic commercial and investment agreements with Medtronic

Mazor Robotics Ltd., a leading developer of innovative bone mounted surgical robotic guidance systems, today entered into two strategic agreements with Medtronic plc (NYSE: MDT). One agreement is a two-stage, multi-faceted, commercial agreement for co-promotion, co-development and, upon meeting certain milestones, potential global distribution of certain Mazor products. The second agreement is for an equity investment by Medtronic in Mazor.

19 May 2016

CGT, University of Aberdeen announce creation of new company to develop novel technology for diabetes treatment

The Cell and Gene Therapy Catapult and University of Aberdeen, UK, today announce the creation of Islexa, a new company developing a novel technology to produce laboratory grown islets, the organoids responsible for insulin production.

18 May 2016

First-ever clinical trial of bioabsorbable cardiovascular device in children shows promise

Current cardiovascular valve or blood vessel implants are generally associated with a number of complications, have limited efficacy over time, and may necessitate repeated interventions over a patient's lifetime, especially when implanted in a young child.

18 May 2016

COPD exacerbations accelerate lung decline

In patients with chronic obstructive pulmonary disease (COPD), exacerbations accelerated lung function loss, according to a new study presented at the ATS 2016 International Conference. The effect was particularly prominent in those with mild disease.

17 May 2016

Boehringer Ingelheim presents new data on OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF)

New analyses presented at the American Thoracic Society’s 2016 annual conference (ATS 2016) further add to the efficacy and safety profile of OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF).

16 May 2016

Important signs, symptoms of stroke that everyone should know

Almost 795,000 Americans suffer from stroke each year, 130,000 which are fatal, making stroke the fifth leading cause of death in the United States.

13 May 2016

Arterial switch to 12 o'clock position linked to myocardial ischaemia risk in adolescence

Arterial switch to the 12 o'clock position is associated with abnormal coronary perfusion in adolescence, reveals research presented today at EuroCMR 2016.1 Babies born with transposition of the great arteries (TGA) undergo the arterial switch operation in the first days of life.

13 May 2016

CT News and Research

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

Oncologists combine two different types of immunotherapy to successfully treat metastatic melanoma

UTHealth's Mobile Stroke Unit fights stroke through research, technology and patient care

Study explores history of penumbra in untreated acute stroke patients

Study explores differences in neuroimaging utilization for stroke from population perspective

New, screen-printed, flexible MRI coils could lead to shorter scan time periods

CGT, CTM CRC collaborate to test patented scaffold technology for commercial scale cell expansion systems

Clinical study supports safety, efficacy of GI Windows’ IAS as treatment option for Type 2 diabetes

ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

Early diagnosis of lung cancer can increase survival rate by 73%

Multimodal therapy may improve survival of pancreatic cancer patients

Radiation-immunotherapy combination can help treat melanoma

Simple sarcopenia screening method could easily diagnose severity of heart disease

Mazor Robotics signs strategic commercial and investment agreements with Medtronic

CGT, University of Aberdeen announce creation of new company to develop novel technology for diabetes treatment

First-ever clinical trial of bioabsorbable cardiovascular device in children shows promise

COPD exacerbations accelerate lung decline

Boehringer Ingelheim presents new data on OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF)

Important signs, symptoms of stroke that everyone should know

Arterial switch to 12 o'clock position linked to myocardial ischaemia risk in adolescence

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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