Immune Response News and Research

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Simple and rapid method measures T-cell immune response to SARS-CoV-2 virus

Researchers from Duke-NUS Medical School, together with collaborators from the National Centre for Infectious Diseases (NCID) and Singapore General Hospital (SGH), have discovered a simple and rapid method to measure the T-cell immune response to the SARS-CoV-2 virus, which causes COVID-19.

3 Sep 2021

World renowned immunologist named chief of Feinberg's Division of Allergy and Immunology

Stephanie Eisenbarth, MD, PhD, has been named chief of Feinberg's Division of Allergy and Immunology in the Department of Medicine, and director of the newly formed Center for Human Immunobiology.

2 Sep 2021

Simple blood test enables early detection of immunotherapy-triggered encephalitis

Immunotherapy is very effective for many cancers, but the treatment can also cause autoimmune side effects. Encephalitis is one of the most serious and difficult-to-diagnose side effects of immunotherapy.

2 Sep 2021

Double vaccination reduces the risk of Long COVID by almost half

Adults who have received a double vaccination are 49% less likely to have Long COVID should they contract a COVID-19 infection.

2 Sep 2021

Should pregnant women be vaccinated against COVID-19?

A recent study examines whether COVID-19 risks in pregnant women justify the administration of COVID-19 vaccines to pregnant individuals.

2 Sep 2021

International taskforce recommends neurocognitive tests to harmonize assessment of long COVID

An international taskforce created by a UNSW Science psychology researcher has recommended a set of neurocognitive and mental health questionnaires to harmonize the assessment of patients with long COVID.

2 Sep 2021

Study identifies how immune sensors launch a multi-faceted innate immune response to infections

St. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and launch a multi-faceted innate immune response to infections with live viruses and bacteria. The discovery appears today in Nature.

2 Sep 2021

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Sepsis is the leading cause of death in Brazil's intensive care units (ICUs). Among patients who progress to the severe form of the disease, 40% die, and the survivors often suffer from cardiovascular and neurological complications, as well as a significant decline in immunity lasting for years after they are discharged from hospital.

2 Sep 2021

Immune cells present in tumors from head and neck cancer patients, study reports

A new study from scientists at Emory Vaccine Center and Winship Cancer Institute of Emory University reports that the immune cells that are the major targets of immune checkpoint inhibitors are present in tumors from head and neck cancer patients.

2 Sep 2021

An assessment of post-vaccination immune response to SARS-CoV-2 Delta in elderly and health care workers

A new cohort study comparing immune responses among vaccinated elderly persons and healthcare workers has been conducted.

2 Sep 2021

Study shows bacille Calmette-Guérin vaccine can protect mice against lethal SARS-CoV-2 challenge

A recent US study, currently available on bioRxiv* preprint server, implies that vaccination with bacille Calmette-Guérin (BCG) can limit the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by targeting innate immune pathways and could thus be used as a platform for pinpointing early immunologic events affecting the outcome of coronavirus disease (COVID-19).

1 Sep 2021

Do kidney transplant recipients need a third booster dose of mRNA COVID-19 vaccine?

A team of researchers in France have observed that the “standard” 2 dose regimen for mRNA COVID-19 vaccines could provide adequate protection to only a few KTRs. It has also been shown in multiple studies that a considerable population of vaccinated KTRs were easily infected with SARS-CoV-2.

1 Sep 2021

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

More than a year after the start of the COVID-19 pandemic, several vaccines have been authorized thanks to unprecedented worldwide research efforts. These first-generation vaccines bring great hope and are a mainstay in fighting the virus.

1 Sep 2021

Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

A new study published in mBio investigates the impact of the furin cleavage site on viral growth and pathogenesis.

31 Aug 2021

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

A new study published in mBio discusses the microevolution of SARS-CoV-2.

31 Aug 2021

Investigational vaccine does not provide sufficient protection against HIV infection

An investigational HIV vaccine tested in the "Imbokodo" clinical trial conducted in sub-Saharan Africa posed no safety concerns but did not provide sufficient protection against HIV infection, according to a primary analysis of the study data. The Phase 2b proof-of-concept study, which began in November 2017, enrolled 2,637 women ages 18 to 35 years from five countries.

31 Aug 2021

J&J COVID-19 booster shot produces robust antibody response

The study showed neutralizing antibody responses produced by the Johnson & Johnson–Janssen vaccine was robust and stable eight months after immunization.

31 Aug 2021

Researchers develop adult lung organoids that represent all cell types

Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived.

31 Aug 2021

Research highlights the importance of meninges for brain development and pathology

A new study, led by researchers at the University of Gothenburg, have generated the first comprehensive transcriptional atlas of neonatal mouse meningeal leukocytes, under normal conditions and after perinatal brain injury.

31 Aug 2021

Coronavirus buildup in the lungs is likely behind high mortality rates

A buildup of coronavirus in the lungs is likely behind the steep mortality rates seen in the pandemic, a new study finds.

31 Aug 2021

Immune Response News and Research

Simple and rapid method measures T-cell immune response to SARS-CoV-2 virus

World renowned immunologist named chief of Feinberg's Division of Allergy and Immunology

Simple blood test enables early detection of immunotherapy-triggered encephalitis

Double vaccination reduces the risk of Long COVID by almost half

Should pregnant women be vaccinated against COVID-19?

International taskforce recommends neurocognitive tests to harmonize assessment of long COVID

Study identifies how immune sensors launch a multi-faceted innate immune response to infections

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Immune cells present in tumors from head and neck cancer patients, study reports

An assessment of post-vaccination immune response to SARS-CoV-2 Delta in elderly and health care workers

Study shows bacille Calmette-Guérin vaccine can protect mice against lethal SARS-CoV-2 challenge

Do kidney transplant recipients need a third booster dose of mRNA COVID-19 vaccine?

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

Investigational vaccine does not provide sufficient protection against HIV infection

J&J COVID-19 booster shot produces robust antibody response

Researchers develop adult lung organoids that represent all cell types

Research highlights the importance of meninges for brain development and pathology

Coronavirus buildup in the lungs is likely behind high mortality rates

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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