Protein C News and Research

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Proteins in blood may help to predict Parkinson’s disease up to seven years before the onset of motor symptoms

Researchers combined mass spectrometry-based proteomic phenotyping with machine learning to identify blood biomarkers in early Parkinson's disease.

20 Jun 2024

Study reveals cognitive benefits of ketogenic diet in aged mice

The impact of cyclic ketogenic diet treatments in improving the age-related decline in brain function.

20 Jun 2024

AI-driven blood test offers hope for early Parkinson's diagnosis

A team of researchers, led by scientists at UCL and University Medical Center Goettingen, Germany, have developed a simple blood test that uses artificial intelligence (AI) to predict Parkinson's up to seven years before the onset of symptoms.

19 Jun 2024

Harnessing post-translational modifications for a tuberculosis booster vaccine

Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide.

19 Jun 2024

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

A genetic treatment targeting the causal NRAS c.181C>A mutation in congenital melanocytic naevus.

19 Jun 2024

Nuts can be part of a healthy weight loss plan, study shows

Whether they’re sprinkled on your morning cereal or kept for an afternoon snack, a handful of nuts could be the next best thing when it comes to weight loss.

19 Jun 2024

Novel AI tool poised to reshape virtual screening in early stage drug discovery

Australian researchers, led by Monash University, have invented a new artificial intelligence (AI) tool which is poised to reshape virtual screening in early stage drug discovery and enhance scientists’ ability to identify potential new medicines.

19 Jun 2024

Researchers propose a 'protein aggregation clock' to measure aging and health

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU), who are also adjunct directors at the Institute of Molecular Biology (IMB) in Mainz, propose the concept of a "protein aggregation clock" to measure ageing and health in a new perspective article published in Nature Cell Biology.

19 Jun 2024

Targeting DUSP6 protein to prevent breast cancer recurrence

Treatment outcomes for breast cancer have become better over the years, but proportion of breast cancers still recur even after long periods without signs of cancer remaining dormant in the body.

19 Jun 2024

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

It's been enormously difficult to pinpoint the cause of many cancers - and many seem to have more than one origin. Fibrolamellar carcinoma (FLC), however, is one that scientists thought they had nailed down.

18 Jun 2024

CCDC leverages computing power of Intel and AWS for advancement in drug discovery

Thanks to the combined computing power of Amazon Web Services (AWS) and Intel, the CCDC announces that a potentially significant advancement in drug discovery has been achieved.

18 Jun 2024

Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP

In a study with 991 adults, scientists at DZNE show that the most common forms of frontotemporal dementia (FTD) as well as the neurological diseases amyotrophic lateral sclerosis (ALS) and progressive supranuclear palsy (PSP) can be recognized by blood testing.

18 Jun 2024

Interdisciplinary team reveals how Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy

A new paper from an interdisciplinary team at MUSC Hollings Cancer Center describes how the bacteria Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy, allowing oral cancer tumors to become resistant to the drug's effects.

18 Jun 2024

New hope for GI cancers: Review analyzes molecular targets and treatment advancements

Gastrointestinal (GI) cancers, encompassing esophageal, gastric, small bowel, and colorectal carcinomas, represent a significant global health burden due to their high incidence and mortality rates.

18 Jun 2024

Gprc5a identified as potential drug target for treating osteoporosis

Osteoporosis is a skeletal condition that leads to the weakening of bones, making them porous, fragile, and prone to breakage.

18 Jun 2024

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing alpha-synuclein.

18 Jun 2024

New dietary recommendations for patients on latest anti-obesity medications like Ozempic

Researchers provide evidence-based suggestions for nutritional evaluation, treatment, and monitoring in patients taking anti-obesity medications (AOMs).

18 Jun 2024

Open-access atlas unveils the molecular mechanisms of roundworm aging

A new aging atlas gives scientists an in-depth view of how individual cells and tissues in worms age and how different lifespan-extending strategies might stop the clock.

18 Jun 2024

Mitophagy fuels cancer stem cell growth and survival

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, "Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration."

18 Jun 2024

Precise protein design offers hope for damaged hearts and kidneys

Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope for repairing damaged hearts, kidneys, and other organs.

18 Jun 2024

Protein C News and Research

Proteins in blood may help to predict Parkinson’s disease up to seven years before the onset of motor symptoms

Study reveals cognitive benefits of ketogenic diet in aged mice

AI-driven blood test offers hope for early Parkinson's diagnosis

Harnessing post-translational modifications for a tuberculosis booster vaccine

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

Nuts can be part of a healthy weight loss plan, study shows

Novel AI tool poised to reshape virtual screening in early stage drug discovery

Researchers propose a 'protein aggregation clock' to measure aging and health

Targeting DUSP6 protein to prevent breast cancer recurrence

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

CCDC leverages computing power of Intel and AWS for advancement in drug discovery

Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP

Interdisciplinary team reveals how Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy

New hope for GI cancers: Review analyzes molecular targets and treatment advancements

Gprc5a identified as potential drug target for treating osteoporosis

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

New dietary recommendations for patients on latest anti-obesity medications like Ozempic

Open-access atlas unveils the molecular mechanisms of roundworm aging

Mitophagy fuels cancer stem cell growth and survival

Precise protein design offers hope for damaged hearts and kidneys

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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