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FDA expands approved use of G5 Mobile Continuous Glucose Monitoring System

The U.S. Food and Drug Administration today expanded the approved use of Dexcom's G5 Mobile Continuous Glucose Monitoring System to allow for replacement of fingerstick blood glucose (sugar) testing for diabetes treatment decisions in people 2 years of age and older with diabetes.

21 Dec 2016

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Based on the study of cell signalling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic agents used to treat breast cancer (half already in use and the other half in clinical testing phase) has allowed researchers at the Institute for Research in Biomedicine to identify 10 new and previously untested combinations that hold potential for the treatment of breast cancer.

20 Dec 2016

Regular use of common mouthwash can help curb spread of gonorrhoea infections

A commercial brand of mouthwash that is readily available from supermarkets and pharmacies can help curb the growth of the bacteria responsible for gonorrhoea, reveals preliminary research published online in the journal Sexually Transmitted Infections.

20 Dec 2016

Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

Researchers of the TGF-beta and Cancer group of Bellvitge Biomedical Research Institute, in collaboration with King's College London, have unveiled the role of NADPH oxidase NOX4 as an inhibitor of the epithelial-amoeboid transition, a process that contributes to the migration and invasion of tumor cells.

20 Dec 2016

New ASRM embryo transfer simulator garners positive response from reproductive health professionals

ASRM Embryo Transfer Simulator has been successfully deployed over the last 12 months at embryo transfer simulation workshops and training sessions.

From VirtaMed 20 Dec 2016

Leading journal publishes article about ciliate lipases as therapeutic candidates for oral treatment of EPI

Cilian AG, a biopharmaceutical company focused on the development of subunit vaccines, enzymes and monoclonal antibodies, announces that the European Journal of Gastroenterology & Hepatology, the international, peer-reviewed, online publication journal, has published an article entitled: Novel ciliate lipases for enzyme replacement during exocrine pancreatic insufficiency.

20 Dec 2016

Sirt1 plays key role in regenerating glial progenitor cells after hypoxia-induced brain injury in preemies

Developing brains in newborns have a sizable pool of a certain type of immature progenitor cell that can be expanded and induced to replace cells lost to brain injury.

19 Dec 2016

First-in-human study of cell bandage for common sporting knee injury shows promising results

A 'living bandage' made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol.

17 Dec 2016

Calcium channel blockers may be effective drugs against cancer metastasis

Researchers at the University of Turku, Finland have identified a new way of blocking the spread of cancer. Calcium channel blockers, which are used to lower blood pressure, block breast and pancreatic cancer invasion by inhibiting cellular structures.

16 Dec 2016

Small, simple-to-use microfluidic device could speed up adoption of new anti-cancer treatments

RESEARCHERS at the University of Huddersfield have helped develop a lab device that could speed up the adoption of new anti-cancer treatments.

16 Dec 2016

Novel plasma medicine with anti-tumor effect discovered

Nagoya University researchers develop cold plasma-activated Ringer's solution for chemotherapy. The solution has anti-tumor effects in vitro and in vivo that derive from the lactate component.

14 Dec 2016

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

ABIVAX an innovative biotechnology company targeting the immune system to eliminate viral disease, announced today that the Company presented new preclinical data on ABX464, ABIVAX's first-in-class drug candidate for a functional cure of patients with HIV/AIDS, during this week's HIV DART scientific conference in Los Cabos, Mexico.

9 Dec 2016

Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Movement of secretory molecules, such as hormones and digestive enzymes, out of the cell is known as exocytosis. This process is guided by SNARE proteins, which help the fusion of secretory vesicles with the plasma membrane.

8 Dec 2016

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality.

8 Dec 2016

Empa researchers developing solution to magnetically remove bacteria from blood

Blood poisoning is still fatal in more than 50% of cases, but can be cured if treated at an early stage. The highest priority is therefore to act quickly.

8 Dec 2016

New SFU research could revolutionize IVF success rates

Over the past three years, Canadian women desperate to conceive a child endured more than 82,000 attempts to become impregnated using in vitro fertilization (IVF), a reproductive technique that fertilizes a woman's eggs outside of her body.

7 Dec 2016

Queen's University expert to lead new €4m initiative for assessing impact of chemicals on health

A Queen's University Belfast expert is leading a €4m international initiative to investigate whether natural toxins and manmade chemicals are creating potentially dangerous mixtures that affect our natural hormones and cause major illnesses such as cancer, obesity, diabetes or infertility.

7 Dec 2016

VIB scientists reveal how NLRP2 protein plays key role in early embryogenesis and fertility

Led by Prof. Mohamed Lamkanfi (VIB-Ghent University), researchers have demonstrated in animal models that a protein called NLRP2 plays an important role in early embryogenesis, the process of cell division in fertilized eggs that occurs before they implant into the lining of the uterus.

6 Dec 2016

Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

Endometrial microbiota (bacteria in the uterine cavity) play an important role in determining whether women are able to get pregnant via in vitro fertilization (IVF), according to a new study published in the American Journal of Obstetrics and Gynecology.

6 Dec 2016

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs.

1 Dec 2016

in vitro News and Research

FDA expands approved use of G5 Mobile Continuous Glucose Monitoring System

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Regular use of common mouthwash can help curb spread of gonorrhoea infections

Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

New ASRM embryo transfer simulator garners positive response from reproductive health professionals

Leading journal publishes article about ciliate lipases as therapeutic candidates for oral treatment of EPI

Sirt1 plays key role in regenerating glial progenitor cells after hypoxia-induced brain injury in preemies

First-in-human study of cell bandage for common sporting knee injury shows promising results

Calcium channel blockers may be effective drugs against cancer metastasis

Small, simple-to-use microfluidic device could speed up adoption of new anti-cancer treatments

Novel plasma medicine with anti-tumor effect discovered

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Synthetic sgRNA for CRISPR genome editing

Empa researchers developing solution to magnetically remove bacteria from blood

New SFU research could revolutionize IVF success rates

Queen's University expert to lead new €4m initiative for assessing impact of chemicals on health

VIB scientists reveal how NLRP2 protein plays key role in early embryogenesis and fertility

Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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