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HRF inhibitors may provide new therapeutic avenue for treatment of asthma and allergies

La Jolla Institute for Allergy & Immunology scientists have identified the histamine releasing factor (HRF) molecule as a promising target for developing new treatments for a number of allergic reactions including asthma.

3 Dec 2011

Viewpoints: Is Berwick a scapegoat?; Rep. Smith on Kagan; Daschle on health IT

Don Berwick, the prominent pediatrician and Harvard School of Public Health professor who headed the Centers for Medicare and Medicaid Services, has officially stepped down, another victim of Washington's hyper-partisan politics.

3 Dec 2011

Two-thirds of women with catamenial epilepsy have diagnosis of partial epilepsy, study finds

In women of childbearing age with epilepsy, seizure exacerbation may occur either at the time of menstruation or ovulation. Investigators in a specialized epilepsy center have analyzed the data on a group of patients with seizures associated with their menstrual cycles (catamenial seizures) for type of epilepsy, seizure frequency, response to medication, neuroimaging findings, and seizures during pregnancy.

3 Dec 2011

Research roundup: Recession's big impact on men's insurance coverage

Researchers examined three sets of surveillance data and found that of the estimated 1.2 million persons in the United States living with the human immunodeficiency virus, 942,000 persons were aware of their infection. More than three-quarters of those were "linked to care" and among HIV-infected adults in care, "45 percent received prevention counseling, and 89 percent were prescribed antiretroviral therapy."

3 Dec 2011

Latin American, Caribbean national rotavirus immunization campaigns show success, CDC report says

"Fourteen of the 32 countries in Latin America and the Caribbean make the rotavirus vaccine available for all infants via national programs," according to a report published Friday in the CDC's "Morbidity and Mortality Weekly Report," United Press International reports.

3 Dec 2011

Doctors provide tips on toy safety

With the excitement of the holidays, parents and relatives eagerly purchase the hottest toys and latest items for their children. But it's during the hustle and bustle of the season that many fail to buy age appropriate gifts for their children, and they tend to disregard warnings on these toys and gifts to ensure they are safe.

3 Dec 2011

Foster children on Medicaid are overly medicated, says report

A study of five states found that foster children are more likely than other kids to be given mind-altering drugs, including antipsychotics and antidepressants.

3 Dec 2011

Brazil's ANVISA grants registration for child-adapted formulation of benznidazole for Chagas disease

Today, at the occasion of the 4th DNDi Partners' Meeting in Rio de Janeiro, Brazil, Dr Carlos Gadelha, Secretary of Science, Technology and Strategic Products, Brazilian Ministry of Health, announced that Brazil's National Health Surveillance Agency (ANVISA) granted registration of a new paediatric dosage form of benznidazole, developed through a partnership between the Pernambuco State Pharmaceutical Laboratory (LAFEPE) of Brazil and the Drugs for Neglected Diseases initiative (DNDi).

3 Dec 2011

Promising new agent against sarcomas affecting children

MK 1775, a small, selective inhibitor molecule, has been found to be active against many sarcomas when tested by researchers at Moffitt Cancer Center in Tampa, Fla. Their findings, recently appearing in Molecular Cancer Therapeutics, published by the American Association for Cancer Research, suggest that a badly needed new agent against sarcomas - especially sarcomas affecting children - may be at hand.

3 Dec 2011

Multipronged approach needed to conquer malaria

"A malaria vaccine could be a powerful new tool," but "[c]ontrolling mosquitoes and diagnosing malaria remain essential. Among the highest priorities now is to develop new methods to do both," a Bloomberg editorial states.

3 Dec 2011

Institutional discrimination and people's attitudes affect disabled children

Many disabled children fail to reach their full potential because they continue to be marginalised in schools, health and social care, according to new research funded by the Economic and Social Research Council (ESRC).

3 Dec 2011

MK 1775 shows promise against sarcomas

MK 1775, a small, selective inhibitor molecule, has been found to be active against many sarcomas when tested by researchers at Moffitt Cancer Center in Tampa, Fla.

3 Dec 2011

First Edition: December 2, 2011

In today's headlines, reports on congressional efforts to extend a payroll tax break and other work Congress must do before the end of the year -- including the Medicare doc fix.

2 Dec 2011

First study of cortisol awakening response in infants

Cortisol may be the Swiss Army knife of hormones in the human body -- just when scientists think they understand what it does, another function pops up. While many of these functions are understood for adults, much less is known about how cortisol operates in babies and toddlers, especially when it comes to an important phenomenon called the cortisol awakening response, or CAR.

2 Dec 2011

U.S. global AIDS funding faces up to 10% cuts in fiscal 2012

As we approach World AIDS Day, life-saving funding is under attack from multiple fronts, and it couldn't come at a worse time. One of the world's biggest donors, the Global Fund to Fight AIDS, TB and Malaria canceled its next round of funding, because it couldn't secure enough donations.

2 Dec 2011

DNDi highlights lack of healthcare coverage for children with HIV/AIDS

Less than one-quarter (23%) of children with HIV/AIDS who need treatment are getting it, according to a report released by the World Health Organization (WHO) on the occasion of World AIDS Day.

2 Dec 2011

Blocking telomerase increases cancer cells' sensitivity to radiation treatment

Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells' sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research.

2 Dec 2011

New insight into why aminoglycoside antibiotics cause deafness

Peter Steyger's research on hearing is very personal. That's because Steyger - a research scientist with the Oregon Hearing Research Center at Oregon Health & Science University - is deaf. Now Steyger has published groundbreaking research that is as personal as it gets. The study gives scientists new insight into why a specific class of antibiotics causes deafness - the same class of antibiotics that caused Steyger's deafness as a child in England 48 years ago. The study was published this month in Scientific Reports, part of the Nature Publishing Group.

2 Dec 2011

ASH recognizes abstract presenters at 53rd annual meeting in San Diego

The American Society of Hematology (ASH) recognizes the following abstract presenters at the 53rd ASH annual meeting in San Diego, CA, with the highest scoring abstracts in the categories of undergraduate student, medical student, graduate student, resident physician, and postdoctoral fellow.

2 Dec 2011

Obama renews U.S. commitment to ending AIDS in World AIDS Day speech

President Barack Obama on Thursday renewed the U.S. commitment to ending HIV/AIDS in a speech marking World AIDS Day, and was joined by former presidents Bill Clinton, who participated by video, and George W. Bush, who spoke from Tanzania with that country's President, Jakaya Kikwete, the Independent reports.

2 Dec 2011