Hormones News and Research

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No added benefit of aliskiren-amlodipine fixed drug combination for hypertension

The fixed drug combination of aliskiren and amlodipine (trade name: Rasilamlo-) was approved in April 2011 for the treatment of people with hypertension in whom aliskiren or amlodipine alone has an insufficient effect.

23 Mar 2012

UC Riverside to study molecular basis of hormonal regulation of mosquito reproduction

Female mosquitoes require energy for their egg development, which they acquire from vertebrate blood. But by sucking on blood, they become vectors of numerous disease pathogens of human and domestic animals. If the mechanisms that govern their egg production are better understood, novel approaches to controlling the reproduction and population of mosquitoes can be devised.

23 Mar 2012

Study finds higher death rate in calorie-restricted models of IBD

In a surprising result, Michigan State University researchers looking at the effects of diet on bowel disease found that mice on a calorie-restricted diet were more likely to die after being infected with an inflammation-causing bacterial pathogen in the colon.

21 Mar 2012

Obesity gene mutation identified in mice

A new study has found why a mutation in a particular gene can lead to obesity. Mouse experiments suggested the body's message to “stop eating” was blocked if the animals had the mutation. The study, published in Nature Medicine, said the brain's response to appetite hormones was being disrupted.

20 Mar 2012

Study reveals how Bdnf gene mutation contributes to severe obesity

Researchers at Georgetown University Medical Center have revealed how a mutation in a single gene is responsible for the inability of neurons to effectively pass along appetite suppressing signals from the body to the right place in the brain. What results is obesity caused by a voracious appetite.

19 Mar 2012

Exposure to MEHP shortens reproductive life of female mice

Female mouse fetuses exposed to very high doses of a common industrial chemical that makes plastics more pliable develop significant reproductive alterations and precancerous lesions as they grow up, according to a new toxicology study conducted at Brown University.

17 Mar 2012

States considering wide-ranging abortion, contraception legislation give lingering voice to issue

A host of abortion legislation is winding its way through state legislatures: Democrats are focusing on regulating male reproductive health in at least six states; Michigan abortion providers face greater scrutiny; Arizona could require those seeking birth control give a medical reason they need it; and Wisconsin lawmakers decide if a doctor must be present to give abortion pills.

17 Mar 2012

BRG1 gene loss implies lack of response of cells to retinoic acid and steroids

Retinoic acid (vitamin A) and steroids are hormones found in our body that protect against oxidative stress, reduce inflammation and are involved in cellular differentiation processes. One of the characteristics of tumours is that their cells have lost the ability to differentiate; therefore these hormones have useful properties to prevent cancer. Currently, retinoic acid and steroids are being used to treat some types of leukaemia.

16 Mar 2012

Light-to-moderate drinking may reduce risk of stroke in women

Light-to-moderate alcohol consumption has been consistently associated with lower risk of heart disease, but data for stroke are less certain, especially among women.

16 Mar 2012

Clear link between androgenetic alopecia and benign prostate hyperplasia

Spanish scientists have confirmed that there is a clear relationship between androgenetic alopecia (common premature baldness) and benign prostate hyperplasia (BPH), a benign enlargement of the prostate that appears in aging men and is associated with certain hormones as dihydrotestosterone. This condition appears in 50% of men over 60 year old and causes voiding syndrome i.e. urinary frequency.

16 Mar 2012

Sleep less, eat more – Recipe for weight gain

Scientists at the Mayo Clinic in Rochester, Minn., studied a group of 17 healthy volunteers between the ages 18 and 40 for a week in their homes, monitoring how much each of the typically slept and ate.

15 Mar 2012

H. pylori bacteria associated with elevated levels of HbA1c

A new study by researchers at NYU Langone Medical Center reveals that the presence of Helicobacter pylori (H. pylori) bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes.

15 Mar 2012

Many women experience memory problems during menopause, confirms study

The difficulties that many women describe as memory problems when menopause approaches are real, according to a study published today in the journal Menopause, the journal of the North American Menopause Society.

15 Mar 2012

Swaddling babies tight could lead to hip problems

Swaddling babies is back in vogue as many mothers are convinced that wrapping babies tightly makes them feel more secure. However a children's surgeon at Southampton General Hospital has warned that the practice of tight swaddling, where both the arms and legs are wrapped up, is causing an increase in hip problems.

13 Mar 2012

MRI reveals microgravity-induced intracranial hypertension in astronauts

Magnetic resonance imaging (MRI) of the eyes and brains of 27 astronauts who have spent prolonged periods of time in space revealed optical abnormalities similar to those that can occur in intracranial hypertension of unknown cause, a potentially serious condition in which pressure builds within the skull.

13 Mar 2012

Gastrointestinal progenitor cells could be coaxed into making insulin

A study by Columbia researchers suggests that cells in the patient's intestine could be coaxed into making insulin, circumventing the need for a stem cell transplant. Until now, stem cell transplants have been seen by many researchers as the ideal way to replace cells lost in type I diabetes and to free patients from insulin injections.

12 Mar 2012

Gene that causes aggression in men under stress discovered

Scientists have found that “macho” gene that makes men behave more aggressively than women under stress. They say this one gene could explain why men have a 'fight or flight' response while women are more likely to try and defuse the situation. The study has been published in the journal BioEssays.

11 Mar 2012

Scientists believe that ageing can be programmed in the womb

Ageing is a complex process involving physical, psychological, and environmental factors. Scientists believe that ageing can be programmed in the womb. One example of stress during pregnancy is the administration of glucocorticoids, i. e. synthetic stress hormones to accelerate fetal lung maturation in premature labor to allow breathing after birth. Could exposure to these stress hormones have an effect on health later in life?

8 Mar 2012

Study uncovers neural mechanism that links repeated stress with impaired memory

Anyone who has ever been subject to chronic stress knows that it can take a toll on emotions and the ability to think clearly. Now, new research uncovers a neural mechanism that directly links repeated stress with impaired memory.

8 Mar 2012

Novel partnership could transform breast cancer diagnosis

An innovative University of Sydney research partnership with private enterprise could see a radical change in how breast cancer is diagnosed, with the possibility to improve detection rates.

4 Mar 2012