Immune Response News and Research

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The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Shorter survival of multiple myeloma subgroup linked to worse kidney damage

Nearly 20% of patients with multiple myeloma have a form in which they make extreme quantities of one component of the abnormal antibody they are producing, and these so-called "free monoclonal light chains" pile up and damage the kidneys, investigators say.

31 Aug 2021

Novel coating technology increases lifespan and stability of implantable devices

Various human implantable medical devices have been developed in recent years, and they are being used in clinical filed. These devices include brain–machine interfaces, in which a chip is implanted into the brain to enable humans to move machines using only their thoughts, and deep brain stimulators for treating Parkinson's disease and other brain diseases.

31 Aug 2021

Durability of cellular immune memory to SARS-CoV-2 after mRNA vaccination

A recent study, available on the bioRxiv* preprint server, investigated the durability of cellular immune memory after mRNA vaccination against SARS-CoV-2 and whether booster jabs affect the durability of different immune response components. The study included testing for antibodies and cellular immune responses in covid patients and recovered individuals.

31 Aug 2021

Scientists identify potential biomarkers to predict COVID-19 outcomes

A team of scientists from the United States has recently examined the trajectory of early immune biomarkers in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. They have identified specific plasma proteins that can accurately predict the clinical and virological outcomes in SARS-CoV-2 infected patients. The study is currently available on the medRxiv* preprint server.

31 Aug 2021

COVID-19 vaccine elicits antibody responses in nearly 9 out of 10 people taking immunosuppressants

COVID-19 vaccination elicited antibody responses in nearly nine out of 10 people with weakened immune systems, although their responses were only about one-third as strong as those mounted by healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis.

30 Aug 2021

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

A new study published in Scientific Reports identifies the human proteins that share structural similarities with the SARS-CoV-2 proteins.

30 Aug 2021

How early interferon curbs SARS-CoV-2 infection

A new study available in the Journal of Experimental Medicine focuses on the importance of interferon in SARS-CoV-2 infection.

30 Aug 2021

Researchers study the role of low-density granulocytes in COVID-19

Information on granulocytes helps to understand mechanisms associated with covid-19 and other infectious diseases. Such information also promotes the development of better diagnostic methods and therapies.

30 Aug 2021

Sustained and effective response to Janssen COVID-19 vaccine Is enhanced by delayed booster

A new study adds to the data on the optimum interval between the first and second doses of the adenovirus vectored COVID-19 vaccine.

30 Aug 2021

Does SARS-CoV-2 natural infection immunity better protect against the Delta variant than vaccination?

A new study from Israel suggests immunity gained after recovering from a previous COVID-19 infection is more protective against the new Delta variant than vaccine-induced immunity. Natural immunity was estimated to be about 13 times stronger than having two doses of the Pfizer-BioNTech vaccine.

30 Aug 2021

Study reveals how SARS-CoV-2 variants of concern modulate receptor and antibody binding

In a trailblazing engineering effort, Canadian and US researchers indicate that the emergence of novel variants of SARS-CoV-2 stems from the mutations of spike glycoprotein that confer either increased affinity for the host cell receptor or increased antibody evasion.

30 Aug 2021

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Recently, a new study published on the pre-print server bioRxiv* examined the effect that maternal asymptomatic COVID-19 had on decidual and peripheral immune cells during the later stage of pregnancy.

30 Aug 2021

Next-gen COVID vaccine to make persistent neutralizing antibodies

Presently, there is a need to develop improved versions of COVID-19 vaccines that are effective against the SARS-CoV-2 variants of concern (VOC) and can confer long-term protection. Considering the need of the hour, scientists from the University of Sydney in Australia have generated a new COVID-19 vaccine CoVac-II and evaluated its effect against COVID-19 strains. The findings from this study are published on the bioRxiv* preprint server while awaiting peer review.

30 Aug 2021

Immune Response News and Research

The tale of mRNA vaccines: Turning calamity into opportunity

Shorter survival of multiple myeloma subgroup linked to worse kidney damage

Novel coating technology increases lifespan and stability of implantable devices

Durability of cellular immune memory to SARS-CoV-2 after mRNA vaccination

Scientists identify potential biomarkers to predict COVID-19 outcomes

COVID-19 vaccine elicits antibody responses in nearly 9 out of 10 people taking immunosuppressants

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

How early interferon curbs SARS-CoV-2 infection

Researchers study the role of low-density granulocytes in COVID-19

Sustained and effective response to Janssen COVID-19 vaccine Is enhanced by delayed booster

Does SARS-CoV-2 natural infection immunity better protect against the Delta variant than vaccination?

Study reveals how SARS-CoV-2 variants of concern modulate receptor and antibody binding

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Next-gen COVID vaccine to make persistent neutralizing antibodies

Northwestern researchers continue investigation on all aspects of COVID-19 pandemic

NIH begins clinical trial to assess extra COVID-19 vaccine dose in people with autoimmune disease

MS patients on anti-CD20 therapy have robust T cell responses to SARS-CoV-2 vaccination

'Humanized' mouse model beats current approaches for finding the best organ donor

Study: One half of hospitalized COVID-19 patients experience persistent symptoms after one year

Study examines safety of COVID-19 vaccine in a nationwide mass-vaccination setting

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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