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Cypin protein may prevent long-term brain damage after stroke

One of two proteins that regulate nerve cells and assist in overall brain function may be the key to preventing long-term damage as a result of a stroke, the leading cause of disability and third leading cause of death in the United States.

3 Nov 2011

Zalicus third quarter revenue increases to $2.4 million

Zalicus Inc. today reported financial results for the third quarter ended September 30, 2011.

2 Nov 2011

Scientists discover how toxic form of htt protein causes Huntington's symptoms

Scientists at the Gladstone Institutes have discovered how a form of the protein linked to Huntington's disease influences the timing and severity of its symptoms, offering new avenues for treating not only this disease, but also a variety of similar conditions.

31 Oct 2011

Researchers identify FMRP protein as key player in RNA editing

The most common form of heritable cognitive impairment is Fragile X Syndrome, caused by mutation or malfunction of the FMR1 gene. Loss of FMR1 function is also the most common genetic cause of autism. Understanding how this gene works is vital to finding new treatments to help Fragile X patients and others.

31 Oct 2011

'Deep sequencing' technology identifies new target area for depression

Scientists at the Texas Biomedical Research Institute and Yale University have identified a new target area in the human genome that appears to harbor genes with a major role in the onset of depression.

29 Oct 2011

Study: Reduced secretion of beta-amyloid signals beginning of Alzheimer's

For decades the amyloid hypothesis has dominated the research field in Alzheimer's disease. The theory describes how an increase in secreted beta-amyloid peptides leads to the formation of plaques, toxic clusters of damaged proteins between cells, which eventually result in neurodegeneration. Scientists at Lund University, Sweden, have now presented a study that turns this premise on its head.

29 Oct 2011

Writer's description of facial vividness linked to mirror neuron system

Celebrated writers such as Charles Dickens and George Eliot described characters' faces vividly without going into detail about their features, according to a research group led at the University of Strathclyde.

22 Oct 2011

Two proteins bind together to ignite and sustain malignant brain tumors

Two previously unassociated proteins known to be overly active in a variety of cancers bind together to ignite and sustain malignant brain tumors, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports this week in the journal Cancer Cell.

22 Oct 2011

Preclinical data from Teva's COPAXONE study on multiple sclerosis

Teva Pharmaceutical Industries Ltd. today announced preclinical data demonstrating reparative and neuroprotective effects of treatment with COPAXONE (glatiramer acetate injection) in experimental autoimmune encephalomyelitis (EAE) models.

21 Oct 2011

OPHN1 protein mediates mGluR-dependent longterm depression at synapses

Scientists at Cold Spring Harbor Laboratory (CSHL) have solved part of a puzzle concerning the relationship between changes in the strength of synapses - the tiny gaps across which nerve cells in the brain communicate - and dysfunctions in neural circuits that have been linked with drug addiction, mental retardation and other cognitive disorders.

20 Oct 2011

New, more effective DBS paradigm may manage Parkinson's symptoms

Parkinson's disease (PD) is a devastating and incurable disease that causes abnormal poverty of movement, involuntary tremor, and lack of coordination. A technique called deep brain stimulation (DBS) is sometimes used to improve motor symptoms in patients with advanced disease. Now, a study published by Cell Press in the October 20 issue of the journal Neuron describes a new and more effective DBS paradigm that makes real-time adjustments in response to disease dynamics and progression and may be better for managing symptoms of advanced PD.

20 Oct 2011

Melbourne Brain Centre to open on Monday

Melbourne will become a magnet for the world's best and brightest brain researchers after the official opening of the Melbourne Brain Centre at The University of Melbourne Parkville by the Premier Ted Baillieu and Federal MP Michael Danby on Monday.

19 Oct 2011

NIH awards Einstein College of Medicine $5.7M for children's IDD Research Center

The Eunice Kennedy Shriver National Institute for Child Health and Human Development, part of the National Institutes of Health, has awarded researchers at Albert Einstein College of Medicine of Yeshiva University $5.7 million to fund the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center (IDDRC).

18 Oct 2011

Brain tumour discovery offers drug treatment hope

Australian scientists have played a key role in the identification of a new biochemical mechanism that allows brain tumours to survive and grow, offering hope of new drug treatments for some of the most aggressive tumours.

17 Oct 2011

AANEM Foundation strengthens and expands research initiatives

The AANEM Foundation for Research and Education has strengthened and expanded its research initiatives. It now will fund one $500,000 grant (up to $100,000 per year for 5 years).

13 Oct 2011

Brain smells what it expects rather than what it sniffs

In the moments before you "stop and smell the roses," it's likely your brain is already preparing your sensory system for that familiar floral smell. New research from Northwestern Medicine offers strong evidence that the brain uses predictive coding to generate "predictive templates" of specific smells -- setting up a mental expectation of a scent before it hits your nostrils.

7 Oct 2011

New insight into mechanisms of hippocampal rhythms

A research team from Berlin, Munich and Haifa has presented new findings concerning the function of the hippocampus, a region of the brain that is important for memory formation.

7 Oct 2011

Alzheimer's may originate in a form similar to that of infectious prion diseases

The brain damage that characterizes Alzheimer's disease may originate in a form similar to that of infectious prion diseases such as bovine spongiform encephalopathy (mad cow) and Creutzfeldt-Jakob, according to newly published research by The University of Texas Health Science Center at Houston.

4 Oct 2011

UCLA neuro-physicists discover optimal brain rhythm for changing synaptic strength

The brain learns through changes in the strength of its synapses -- the connections between neurons -- in response to stimuli. Now, in a discovery that challenges conventional wisdom on the brain mechanisms of learning, UCLA neuro-physicists have found there is an optimal brain "rhythm," or frequency, for changing synaptic strength. And further, like stations on a radio dial, each synapse is tuned to a different optimal frequency for learning.

4 Oct 2011

Researchers discover kibra protein controls sculpting of brain circuitry

Researchers working with adult mice have discovered that learning and memory were profoundly affected when they altered the amounts of a certain protein in specific parts of the mammals' brains.

29 Sep 2011