Precision Medicine News and Research

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Experimental Therapeutics, Debiopharm join to develop oral small molecules targeting new class of epigenetic modulators

The Agency for Science, Technology and Research (A*STAR)'s Experimental Therapeutics Centre (ETC), a center of excellence to advance and accelerate drug discovery in Singapore, and Debiopharm Group™ (Debiopharm), the Swiss-based global biopharmaceutical company that focuses on the development of prescription drugs that target unmet medical needs including oncology as well as companion diagnostics, today announced the signature of an exclusive research collaboration to develop oral small molecules targeting new class of epigenetic modulators.

7 Oct 2013

Study shows precision medicine provides better treatment options for mentally ill person

A multidisciplinary team led by a geneticist and psychiatrist from Cold Spring Harbor Laboratory's (CSHL) Stanley Institute for Cognitive Genomics today publish a paper providing a glimpse of both the tremendous power and the current limitations of what is sometimes called "precision medicine."

5 Oct 2013

'Personalised medicine': Topic of free public lecture at the University of Greenwich

'Personalised medicine' is the topic of a free public lecture at the University of Greenwich. Personalised medicine, or precision medicine, as it is sometimes known, is a key goal for 21st century healthcare. Currently, many medicines are either ineffective or unsafe in certain patient populations, whereas the aim for personalised medicine is to target the right treatment to the right patient group.

5 Oct 2013

Findings may result in better management of chronic depression

Virginia Commonwealth University has received a $3 million grant from the National Institute of Mental Health to study key molecular markers found in DNA that predict chronic depression.

2 Oct 2013

Laboratory testing kit that estimates risk of breast cancer relapse gets FDA approval

A laboratory testing kit that estimates the risk of breast cancer relapse in spite of anti-hormone treatment has received approval from the U.S. Food and Drug Administration.

2 Oct 2013

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

A groundbreaking study of nearly 2,300 extremely obese diabetes patients, led by the Translational Genomics Research Institute, has identified genes associated with unhealthy liver function.

2 Oct 2013

Standoff between a mutated gene and normal counterpart keeps certain cancer cells alive

What keeps leukemia cells alive almost forever, able to continue dividing endlessly and aggressively? New research at the Weizmann Institute suggests that, in around a quarter of all leukemias, the cancer cells rely on an internal "balance of terror" to keep going.

1 Oct 2013

Four Geisinger Health System researchers receive $25M grant to initiate ClinGen Project

Four Geisinger Health System researchers have taken center stage in the national arena of genomics thanks to new funding from the National Human Genome Research Institute (NHGRI), an arm of the U.S. National Institutes of Health (NIH).

27 Sep 2013

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Rhythm announced today the initiation of the first of a series of clinical trials with RM-493, the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of obesity in individuals with a genetic deficiency in the MC4R pathway.

24 Sep 2013

Genetics in Medicine's October 2013 issue details solutions for integrating genomic data into EHR

Genetic tests can now tell us whether we are at increased risk of various cancers, heart or kidney disease, asthma and a number of other conditions.

20 Sep 2013

Human breast tumors transplant could be valuable tools in search for better treatments

Breast cancer that spreads to other organs is extremely difficult to treat. Doctors can buy patients time, but a cure remains elusive. Now, researchers at Washington University School of Medicine in St. Louis have shown that human breast tumors transplanted into mice are excellent models of metastatic cancer and could be valuable tools in the search for better treatments.

20 Sep 2013

Ventana, Boehringer Ingelheim to develop companion diagnostic tests for oncology programs

Ventana Medical Systems, Inc., a member of the Roche Group, and Boehringer Ingelheim announced today that they have entered into an agreement to collaborate on the development of companion diagnostic tests for Boehringer Ingelheim oncology programs.

19 Sep 2013

Researchers discover why multiple myeloma recurs after initially effective treatment

Researchers have discovered why multiple myeloma, a difficult to cure cancer of the bone marrow, frequently recurs after an initially effective treatment that can keep the disease at bay for up to several years.

19 Sep 2013

Inside Jersey magazine names Rutgers Cancer Institute of New Jersey physicians among Top Doctors

Several physicians at Rutgers Cancer Institute of New Jersey have been named as a 'Top Doctor' by Inside Jersey magazine.

17 Sep 2013

Gentris expands genomic biomarker offering with launch of Affymetrix GeneChip HTA services

Gentris Corporation, a global leader in pharmacogenomics and biorepository solutions, announced today that it is expanding its genomic biomarker offering with the launch of Affymetrix GeneChip Human Transcriptome Array services.

17 Sep 2013

Studying Tumor Mutations Via A Network Approach

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16 Sep 2013

New approach subtypes cancers by shared genetic effects; a step toward personalized medicine

Cancer tumors almost never share the exact same genetic mutations, a fact that has confounded scientific efforts to better categorize cancer types and develop more targeted, effective treatments.

16 Sep 2013

Researchers report first experimental evidence that supports theory of buckyball

Researchers at the Virginia Tech Carilion Research Institute have reported the first experimental evidence that supports the theory that a soccer ball-shaped nanoparticle commonly called a buckyball is the result of a breakdown of larger structures rather than being built atom-by-atom from the ground up.

16 Sep 2013

Data can help scientists, physicians match precision drugs to cancer's genetic traits

More than 5,000 genetic profiles of tumor DNA have been completed in a large research study by scientists at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Boston Children's Hospital designed to speed the development of personalized cancer care with precision treatments.

13 Sep 2013

NIH budget slashing may stall future pain research funding

Multi-faceted pain research discoveries within the last decade are bringing new hope for the estimated 100 million Americans with chronic pain. Unfortunately, translation of these scientific advances into clinical practice could be stalled without sufficient funding for both basic science and clinical pain research, according to the American Pain Society.

12 Sep 2013

Precision Medicine News and Research

Experimental Therapeutics, Debiopharm join to develop oral small molecules targeting new class of epigenetic modulators

Study shows precision medicine provides better treatment options for mentally ill person

'Personalised medicine': Topic of free public lecture at the University of Greenwich

Findings may result in better management of chronic depression

Laboratory testing kit that estimates risk of breast cancer relapse gets FDA approval

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

Standoff between a mutated gene and normal counterpart keeps certain cancer cells alive

Four Geisinger Health System researchers receive $25M grant to initiate ClinGen Project

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Genetics in Medicine's October 2013 issue details solutions for integrating genomic data into EHR

Human breast tumors transplant could be valuable tools in search for better treatments

Ventana, Boehringer Ingelheim to develop companion diagnostic tests for oncology programs

Researchers discover why multiple myeloma recurs after initially effective treatment

Inside Jersey magazine names Rutgers Cancer Institute of New Jersey physicians among Top Doctors

Gentris expands genomic biomarker offering with launch of Affymetrix GeneChip HTA services

Studying Tumor Mutations Via A Network Approach

New approach subtypes cancers by shared genetic effects; a step toward personalized medicine

Researchers report first experimental evidence that supports theory of buckyball

Data can help scientists, physicians match precision drugs to cancer's genetic traits

NIH budget slashing may stall future pain research funding

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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