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New tool offers high accuracy in the interpretation of genetic mutations in disease genes

Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic mutations, even among well-studied disease genes, remains difficult.

21 Apr 2023

UT Southwestern expert says common skin problems could signal a more serious rheumatic disease

While rheumatic diseases typically affect the joints, muscles, or ligaments, the first signs of a problem may appear on the skin.

21 Apr 2023

Study: Geographic disparities in mortality are different than previously assumed

By looking at where people were born instead of where they ultimately move to and die, geographic disparities in mortality look different than previously assumed, according to a new study published on April 1, 2023, in the journal Demography.

21 Apr 2023

Large-scale study identifies factors linked to uptake of first COVID-19 vaccination dose

A large-scale registry study in Finland has identified several factors associated with uptake of the first dose of COVID-19 vaccination. In particular, persons with low or no labor income and persons with mental health or substance abuse issues were less likely to vaccinate.

21 Apr 2023

Childhood adversity may increase risk of developing type 2 diabetes in early adulthood

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD])finds that individuals who experienced childhood adversity are at increased risk of developing type 2 diabetes (T2D) in early adulthood.

21 Apr 2023

New injectable cell therapy shows promise for treating osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

21 Apr 2023

Most kids recover from Lyme disease within six months of completing antibiotic treatment

A majority of parents of children diagnosed with Lyme disease reported that their kids recovered within six months of completing antibiotic treatment, according to a new joint study from Children's National Research Institute and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, published in Pediatric Research.

21 Apr 2023

How alcohol intake contributes to increased pain and hypersensitivity

Chronic alcohol consumption may make people more sensitive to pain through two different molecular mechanisms - one driven by alcohol intake and one by alcohol withdrawal.

21 Apr 2023

Medical test for heart injury could be used to help COVID-19 patients avoid hospitalization

A study led by the University of St Andrews suggests that a frequently used medical test for heart injury could one day be used to help COVID-19 patients avoid hospitalization.

21 Apr 2023

Researchers identify a type of immune cell that drives chronic organ transplant failure

University of Pittsburgh researchers have identified a type of immune cell that drives chronic organ transplant failure in a mouse model of kidney transplantation and uncovered pathways that could be therapeutically targeted to improve patient outcomes.

21 Apr 2023

Super-polymers are used by gut bacteria to fend off antibiotics

The discovery shows why it can be so difficult to tackle drug-resistant bacteria, but does provide a possible avenue for tackling the problem.

21 Apr 2023

New sensing platform for detecting biological markers related to cancers

When doctors are examining suspected cancer cases, they turn to biomarker tests to help make a diagnosis.

21 Apr 2023

Greenness around the home does not protect children from atopic eczema

According to a new Finnish study, greenness around the home in early childhood does not seem to protect children from atopic eczema.

21 Apr 2023

Weight loss surgery more effective for the treatment of non-alcoholic fatty liver disease

Metabolic (bariatric) surgery is more effective than medications and lifestyle interventions for the treatment of advanced non-alcoholic fatty liver disease.

21 Apr 2023

Lymphoma risk is slightly elevated in patients with IBD

The risk of developing lymphoma is slightly elevated in inflammatory bowel disease (IBD) and has increased in recent years in patients with Crohn's disease, report researchers from Karolinska Institutet in a study published in Clinical Gastroenterology and Hepatology.

21 Apr 2023

U-M to launch a population-based study on Alzheimer’s disease and related dementias in India

The University of Michigan is looking to launch a population-based study on Alzheimer’s disease and related dementias in India.

21 Apr 2023

Research reveals a more effective treatment for multiple sclerosis patients

Degeneration of myelin, an insulating sheath required for rapid communication between nerve cells, and neuroinflammation are notable hallmarks of Multiple Sclerosis (MS) and related neurodegenerative disorders such as Alzheimer's disease or Huntington's disease that affect roughly 2.8 million people in the world.

21 Apr 2023

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

Researchers at Cleveland Clinic have taken an important step in predicting which treatment will work for individual cancer patients.

21 Apr 2023

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

The maternal mortality sustainable development goals are unlikely to be met by 2050, study suggests

Study developed a Global Maternal Health microsimulation model to measure global maternal death incidence.

21 Apr 2023

Research News and Research

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

UT Southwestern expert says common skin problems could signal a more serious rheumatic disease

Study: Geographic disparities in mortality are different than previously assumed

Large-scale study identifies factors linked to uptake of first COVID-19 vaccination dose

Childhood adversity may increase risk of developing type 2 diabetes in early adulthood

New injectable cell therapy shows promise for treating osteoarthritis

Most kids recover from Lyme disease within six months of completing antibiotic treatment

How alcohol intake contributes to increased pain and hypersensitivity

Medical test for heart injury could be used to help COVID-19 patients avoid hospitalization

Researchers identify a type of immune cell that drives chronic organ transplant failure

Super-polymers are used by gut bacteria to fend off antibiotics

New sensing platform for detecting biological markers related to cancers

Greenness around the home does not protect children from atopic eczema

Weight loss surgery more effective for the treatment of non-alcoholic fatty liver disease

Lymphoma risk is slightly elevated in patients with IBD

U-M to launch a population-based study on Alzheimer’s disease and related dementias in India

Research reveals a more effective treatment for multiple sclerosis patients

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

The maternal mortality sustainable development goals are unlikely to be met by 2050, study suggests

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