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What protects killer T cells from accidental death?

White blood cells, which release a toxic potion of proteins to kill cancerous and virus-infected cells, are protected from any harm by the physical properties of their cell envelopes, find scientists from UCL and the Peter MacCallum Cancer Centre in Melbourne.

27 Nov 2019

Looking for the source: new routes for allergy treatment

A new multinational study has reported a very full account of the B lymphocytes that produce group E antibodies, also called IgE (Immunoglobulin E), that are behind allergic reactions, which are common in up to a third of the world’s population.

26 Nov 2019

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

While estrogen receptor - + breast cancers express high levels of three anti-apoptotic Bcl-2 family members, pharmacological inhibition of Bcl-2 and/or Bcl-xL fails to induce cell death in ER + breast cancer cell lines, due to rapid and robust Mcl-1 upregulation.

26 Nov 2019

Obese teenagers at risk for brain damage, suggests new study

A new study being presented at the yearly conference of the Radiological Society of North America (RSNA) reports that MRI scanning of the brain shows signs of brain damage in obese adolescents – and that these signs could be the result of brain inflammation.

25 Nov 2019

Exploring the link between macular degeneration and retinitis pigmentosa

Four words you never want to hear from the eye doctor are retinitis pigmentosa and macular degeneration.

25 Nov 2019

Research shows how cilia and exocyst contribute to extracellular vesicle production

Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology.

25 Nov 2019

Thermal imaging has potential to assess rheumatoid arthritis

A new study, published today in Scientific Reports, highlights that thermal imaging has the potential to become an important method to assess Rheumatoid Arthritis.

25 Nov 2019

New tool uses tiny circuits made of DNA to identify cancer cells

A new cancer-detecting tool uses tiny circuits made of DNA to identify cancer cells by the molecular signatures on their surface.

22 Nov 2019

Researchers discover new active substance effective against gram negative bacteria

More and more bacterial pathogens of infectious diseases become resistant to customary antibiotics. Typical hospital germs such as Escherichia coli and Klebsiella pneumoniae have become resistant to the most - and in some cases even all - currently available antibiotics. Their additional external membrane makes these bacteria difficult to attack.

21 Nov 2019

Special protective membrane reduces build-up of fibrotic tissue around pacemakers

ETH scientists have developed a special protective membrane made of cellulose that significantly reduces the build-up of fibrotic tissue around cardiac pacemaker implants, as reported in the current issue of the journal Biomaterials.

21 Nov 2019

Researchers turn to older treatment methods for new health challenges

The last thing anyone wants during a stay in the hospital is a hospital-acquired infection. Nosocomial infections, as they are called, are on the rise as more pathogens become resistant to drugs currently available.

21 Nov 2019

Recently discovered protein may play key role in obesity and metabolic disease

With unexpected findings about a protein that's highly expressed in fat tissue, scientists at Scripps Research have opened the door to critical new understandings about obesity and metabolism.

21 Nov 2019

Researchers elucidate role of inflammation resolution sensor in obesity and heart failure

After heart attack injury, several fatty-acid-derived bioactive molecules -- including one called resolvin D1 -- play an essential signaling role to safely clear inflammation and help repair heart muscle. The mechanism of how this resolution occurs is not well-understood.

20 Nov 2019

Cell factors decide if a cancer grows or dies, says new study

A new study published today in the journal Cell Reports by scientists at the German Cancer Research Center (DKFZ) shows that the direction taken by a cancer cell depends on the configuration of the cell itself as well as the activation of a universal cancer cell receptor called CD95.

19 Nov 2019

Using 'Trojan horses' to kill tumor cells from within

Using "Trojan horses" to combat cancer from within the tumor cells themselves without damaging healthy tissues is the aim of this new tool created by researchers from the University of Granada, the Institute of Nanoscience of Aragon, the University of Zaragoza, and the Cancer Research UK Edinburgh Centre at the University of Edinburgh.

19 Nov 2019

25 years of research to fight cervical cancer

According to the World Health Organization, cervical cancer is the fourth most common type of cancer affecting women worldwide. Currently, early screenings of pre-cancerous tissues and vaccination have proven to be the most effective treatment strategies.

19 Nov 2019