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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

TGF--1 suppresses the growth of cancer cells, find researchers

UT Southwestern Medical Center researchers have found that a naturally occurring protein -- transforming growth factor beta1 (TGF--1) -- which normally suppresses the growth of cancer cells, causes a rebound effect after a prolonged exposure.

2 Dec 2009

New scientific breakthrough may allow doctors to reverse cleft palate in humans

In a study newly published in the journal Development, investigators at the USC School of Dentistry describe how to non-surgically reverse the onset of cleft palate in fetal mice - potentially one step in the journey to a better understanding of similar defects in humans.

2 Dec 2009

Canadians with hemophilia A can use new treatment option, XYNTHA

Canadians with hemophilia A - a rare, inherited blood-clotting disorder - now have a new treatment option with the introduction of XYNTHA(TM), a recombinant factor VIII product for both the control and prevention of bleeding episodes and surgical prophylaxis.

2 Dec 2009

Antipsychotic medications increase the levels of inflammation markers, find researchers

Overall, antipsychotic medications are reasonably effective, and fairly well tolerated treatments for mood and psychotic disorders. However, treatment with a number of antipsychotic medications is associated with weight gain, and for some, hyperglycemia and hyperlipidemia.

2 Dec 2009

Acceleron Pharma announces study results of its ACE-011 and ACE-536 blood forming agents

Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth of cells and tissues including red blood cells, bone, muscle, fat, and the vasculature, today announced that results from preclinical and clinical studies of two, novel blood forming agents, ACE-011 and ACE-536, will be presented at the 51st Annual Meeting of the American Society of Hematology at the Ernest N. Morial Convention Center in New Orleans, Louisiana.

1 Dec 2009

Pfizer, Protalix team up to develop and market plant-based enzyme for Gaucher’s disease treatment

Pfizer and Protalix (NYSE-Amex: PLX) today announced that they have entered into an agreement to develop and commercialize taliglucerase alfa, a plant-cell expressed form of glucocerebrosidase (GCD) in development for the potential treatment of Gaucher’s disease.

1 Dec 2009

TAP and pharma company team up to design Sonata, a unique system to speed drug development

The Automation Partnership (TAP), a world leader in the design and development of innovative automation for life science applications, is delighted to announce that its Advanced Projects Group has partnered with a leading pharma company to successfully design and deliver Sonata™, a unique system for automated culturing and processing of cell lines in shake flasks.

1 Dec 2009

Researchers identify better strategies to control weight in adolescents

Adolescent obesity is a major public health problem that impacts one out of every three children, resulting in 4-5 million overweight youth in the United States.

1 Dec 2009

Mechanism blocking HIV-1 from entering cells identified

Publishing in PLoS Pathogens, researchers at from the Kimmel Cancer Center at Jefferson have found a novel mechanism by which drugs block HIV-1 from entering host cells.

1 Dec 2009

DFG approves establishment of new CRCs; research topics range from modern prostheses to political reforms to marine bacteria

The DFG has approved the establishment of 17 new Collaborative Research Centres as of 1 January 2010. This decision was made recently by the relevant Grants Committee in Bonn.

1 Dec 2009

Research shows link between nervous and immune systems; findings may lead to new treatments for autoimmune disorders

New research in the Journal of Leukocyte Biology shows the link between the nervous and immune systems and how breaking that link might lead to new treatments for a wide range of autoimmune disorders

1 Dec 2009

Researchers devise a way to deliver right therapy directly to tumors using aptamers

Finding and treating a tumor without disturbing normal tissue presents challenges - sometimes the most effective therapies can be invasive and harsh.

1 Dec 2009

$2.6M NIH grant for survey of in situ protein-protein interaction networks

Our brain is composed of over one trillion cells called neurons. Each neuron contains millions of proteins. Exactly how individual proteins interact with one another and together form complex signaling networks within neurons has never been examined directly in live animals.

1 Dec 2009

CCII capsules offer safe and effective treatment for rheumatoid arthritis

Chicken collagen can provide relief from rheumatoid arthritis (RA) symptoms. A randomised, controlled trial, published in BioMed Central's open access journal Arthritis Research & Therapy, has found that Chicken type II collagen (CCII), a protein extracted from the cartilage of chicken breast, is a safe and effective treatment for RA.

1 Dec 2009

Investigators identify effective weight control strategies for overweight adolescents

Adolescent obesity is a major public health problem that impacts one out of every three children, resulting in 4-5 million overweight youth in the United States. In a study published in the December 2009 issue of the Journal of the American Dietetic Association, researchers evaluated differences in weight control behaviors, including dietary intake and physical activity, comparing overweight adolescents who lost weight and those who did not in order to better understand which strategies could be most effective.

1 Dec 2009

PanGenex plans to expand its retail product line with the addition of spirulla

PanGenex Corporation, a global nutraceutical and dietary supplement manufacturer and marketer, announced today that it has solidified plans to expand its retail product line with the addition of spirulla.

1 Dec 2009

Aegis Therapeutics signs License Agreement with Roche

Aegis Therapeutics LLC (Aegis) announced today that they have signed a License Agreement providing Roche access to Aegis' proprietary ProTek® stabilization technology. The ProTek® technology covers the use of specific excipients as stabilizers in certain manufacturing processes and formulations of protein-based therapeutics.

1 Dec 2009

ALS research collaboration receives philanthropic funding

Three prominent philanthropic organizations – The Angel Fund, The ALS Therapy Alliance and Project ALS -- dedicated to finding a treatment for amyotrophic lateral sclerosis (ALS) have financed a new collaboration between one of the world’s leading ALS researchers and RXi Pharmaceuticals Corporation, a biopharmaceutical company pursuing the development and commercialization of proprietary therapeutics based on RNA interference (RNAi).

30 Nov 2009

Minerva Biotechnologies grants Clarient exclusive commercializing rights to its MUC1 diagnostic test

Clarient, Inc., a premier technology and services resource for pathologists, oncologists and the pharmaceutical industry, today announced that privately held, Waltham, MA-based Minerva Biotechnologies has granted it the exclusive right to develop and commercialize a test that identifies the MUC1* protein, a biomarker researchers believe may be implicated in the spread of many cancers, including breast cancer.

30 Nov 2009

Study provides new insight into the mechanism of bacterial invasion protein

Spoiled meat is one of the sources for Listeria infections leading to listeriosis. Pregnant women, newborns and immune compromised people are susceptible for a severe progression of this disease. Firstly, the pathogen breaches the intestinal barrier and thus enters the body. The key for further spreading is the invasion protein internalin B that is located on the bacterial surface.

30 Nov 2009

Protein News and Research

Further Reading

TGF--1 suppresses the growth of cancer cells, find researchers

New scientific breakthrough may allow doctors to reverse cleft palate in humans

Canadians with hemophilia A can use new treatment option, XYNTHA

Antipsychotic medications increase the levels of inflammation markers, find researchers

Acceleron Pharma announces study results of its ACE-011 and ACE-536 blood forming agents

Pfizer, Protalix team up to develop and market plant-based enzyme for Gaucher’s disease treatment

TAP and pharma company team up to design Sonata, a unique system to speed drug development

Researchers identify better strategies to control weight in adolescents

Mechanism blocking HIV-1 from entering cells identified

DFG approves establishment of new CRCs; research topics range from modern prostheses to political reforms to marine bacteria

Research shows link between nervous and immune systems; findings may lead to new treatments for autoimmune disorders

Researchers devise a way to deliver right therapy directly to tumors using aptamers

$2.6M NIH grant for survey of in situ protein-protein interaction networks

CCII capsules offer safe and effective treatment for rheumatoid arthritis

Investigators identify effective weight control strategies for overweight adolescents

PanGenex plans to expand its retail product line with the addition of spirulla

Aegis Therapeutics signs License Agreement with Roche

ALS research collaboration receives philanthropic funding

Minerva Biotechnologies grants Clarient exclusive commercializing rights to its MUC1 diagnostic test

Study provides new insight into the mechanism of bacterial invasion protein

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