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Results of darexaban phase II trial in recent acute coronary syndrome presented at ESC Congress

A phase II dose-finding study has found that the new oral Factor Xa inhibitor darexaban was associated with a two to four-fold increase in bleeding when added to dual antiplatelet therapy in patients following an acute coronary syndrome.

30 Aug 2011

Intra-aortic balloon counterpulsation prior to PCI does not reduce infarct size in AMI patients

Inserting intra-aortic balloon pumps prior to angioplasty in patients with acute myocardial infarction (AMI) does not reduce the scope of heart muscle damage, a condition referred to as infarct size, according to a new study conducted by Duke University Medical Center researchers.

30 Aug 2011

Ipsen, Inspiration partner to launch hemophilia product portfolio in Europe

Ipsen and Inspiration Biopharmaceuticals Inc. today announced they have entered into a strategic partnership agreement, to create a European hemophilia commercial organization, to launch Inspiration's hemophilia product portfolio in Europe.

30 Aug 2011

Bristol Meyer Squibb’s new blood thinner drug for stroke prevention

Researchers find that an experimental anticlotting pill Eliquis is more effective than standard drug, warfarin, at preventing strokes in people with a heart condition that puts them at high risk of blood clots and stroke. The new drug also known as apixaban, cut the risk of stroke by 21% compared with warfarin in people with atrial fibrillation (AF). It lowered the risk of dying by 11%.

30 Aug 2011

Dabigatran etexilate superior to warfarin for stroke prevention in AF patients

New data from two RE-LY trial sub-group analyses show that dabigatran etexilate provides consistent benefits in stroke in atrial fibrillation (AF) compared to well-controlled warfarin, irrespective of whether patients use antiplatelet or other concomitant therapies, such as the anti-arrhythmics amiodarone or verapamil.

29 Aug 2011

One in three AF patients at high risk of stroke are not being prescribed VKA therapy

New data show that, worldwide, one in three patients with atrial fibrillation (AF) who are at high risk for stroke are not being prescribed anticoagulant therapy, particularly vitamin K antagonists (VKA) – medicines known to significantly lower stroke risk in these patients.

29 Aug 2011

ELIQUIS better than warfarin in reduction of stroke, major bleeding, and mortality

Bristol-Myers Squibb Company and Pfizer Inc. today announced the main results of the Phase 3 clinical trial ARISTOTLE, which evaluated ELIQUIS compared to warfarin for the prevention of stroke or systemic embolism in 18,201 patients with atrial fibrillation and at least one risk factor for stroke.

29 Aug 2011

AAO-HNSF's 2011 Annual Meeting & OTO EXPO to convene in San Francisco

The 2011 Annual Meeting & OTO EXPO of the American Academy of Otolaryngology - Head and Neck Surgery Foundation (AAO-HNSF), the largest meeting of ear, nose, and throat doctors in the world, will convene September 11-14, 2011, in San Francisco, CA.

29 Aug 2011

Apixaban superior to warfarin in preventing stroke and systemic embolism

A large-scale trial finds that apixaban, a new anticoagulant drug, is superior to the standard drug warfarin for preventing stroke and systemic embolism in patients with atrial fibrillation.

29 Aug 2011

Protein that allows Ebola virus to attack cells discovered

A U.S. research team has discovered a protein called Niemann-Pick C1 (NPC1), which they found was responsible for allowing Ebola virus to enter and replicate within cells.

26 Aug 2011

State-wide QI initiatives seek to improve outcomes of maternal, child care

Maternal/child nurses are at the forefront of efforts to design and implement effective quality improvement (QI) programs to improve care for mothers and infants throughout labor and delivery, according to the special September/October issue of MCN: The American Journal of Maternal/Child Nursing.

26 Aug 2011

Transradial cardiac catheterizations reduce complications, increase patient comfort

Each year, more than one million cardiac catheterizations are performed in the United States, and most of these procedures are performed through the groin to access the arteries that provide blood supply to the heart.

25 Aug 2011

Researchers discover NPC1 protein as crucial for Ebola virus to enter host cells

Although outbreaks are rare, Ebola virus, the cause of Ebola hemorrhagic fever (EHF), is one of the deadliest known viruses affecting humans. According to the World Health Organization (WHO), approximately 1,850 EHF cases with more than 1,200 deaths have been documented since the virus was identified in 1976.

25 Aug 2011

Statin therapy may not be appropriate for certain patients at risk for stroke

For many patients, cholesterol-lowering statin drugs can reduce the risk of strokes as well as heart attacks.

20 Aug 2011

New book on hemophilia, unintended consequences of medical progress

The Bleeding Disease: Hemophilia and the Unintended Consequences of Medical Progress (John Hopkins University Press) is the new book by NJIT Associate Professor Stephen Pemberton. The book recounts the promising and perilous history of medical and social efforts to manage hemophilia in 20th-century America.

19 Aug 2011

Herbal supplements may weaken the effect of chemotherapy drugs

Acai berry, cumin, herbal tea, turmeric and long-term use of garlic - all herbal supplements commonly believed to be beneficial to your health - may negatively impact chemotherapy treatment according to a new report presented at the American Society of Clinical Oncology (ASCO) meeting in Chicago this summer.

18 Aug 2011

Flexible-fiber CO2 laser-assisted ablation safe for endoscopic assisted transsphenoidal craniotomies

A new study has shown the Flexible-Fiber CO2 laser to safely cut and coagulate during endoscopic assisted transsphenoidal craniotomies (TSC) without the line of sight problems encountered with conventional CO2 lasers.

17 Aug 2011

Arrythmia drug may work in stroke prevention: Study

The latest research has revealed that a new drug for treating people with an irregular heartbeat has fewer side effects than the standard treatment and is just as good at cutting the risk of stroke. Rivaroxaban, which is easier for people to take, is as effective as warfarin at preventing blood clots and thus lowering the risk of stroke for patients with atrial fibrillation say researchers.

15 Aug 2011

Anticoagulation service improves quality of care for patients treated with warfarin

A pharmacist-directed anticoagulation service improves the coordination of care from the hospital to an outpatient clinic for patients treated with the anticoagulant drug warfarin, according to a Henry Ford Hospital study.

11 Aug 2011

Biomarker may signal whether common back pain treatment will work

A new study from researchers at the Stanford University School of Medicine has identified a unique protein complex that can be used to predict whether an epidural steroid injection will help relieve pain caused by a herniated disc in the lower spine.

10 Aug 2011

Bleeding News and Research

Results of darexaban phase II trial in recent acute coronary syndrome presented at ESC Congress

Intra-aortic balloon counterpulsation prior to PCI does not reduce infarct size in AMI patients

Ipsen, Inspiration partner to launch hemophilia product portfolio in Europe

Bristol Meyer Squibb’s new blood thinner drug for stroke prevention

Dabigatran etexilate superior to warfarin for stroke prevention in AF patients

One in three AF patients at high risk of stroke are not being prescribed VKA therapy

ELIQUIS better than warfarin in reduction of stroke, major bleeding, and mortality

AAO-HNSF's 2011 Annual Meeting & OTO EXPO to convene in San Francisco

Apixaban superior to warfarin in preventing stroke and systemic embolism

Protein that allows Ebola virus to attack cells discovered

State-wide QI initiatives seek to improve outcomes of maternal, child care

Transradial cardiac catheterizations reduce complications, increase patient comfort

Researchers discover NPC1 protein as crucial for Ebola virus to enter host cells

Statin therapy may not be appropriate for certain patients at risk for stroke

New book on hemophilia, unintended consequences of medical progress

Herbal supplements may weaken the effect of chemotherapy drugs

Flexible-fiber CO2 laser-assisted ablation safe for endoscopic assisted transsphenoidal craniotomies

Arrythmia drug may work in stroke prevention: Study

Anticoagulation service improves quality of care for patients treated with warfarin

Biomarker may signal whether common back pain treatment will work

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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