Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Onconova, SymBio enter commercialization collaboration for rigosertib in Japan and Korea

Onconova Therapeutics, Inc., and SymBio Pharmaceuticals Limited announced today that they will collaborate to develop and commercialize rigosertib in Japan and Korea. Onconova is conducting late-stage clinical trials with rigosertib (ON 01910.Na) in the U.S., Europe and India for the treatment of Myelodysplastic Syndromes (MDS) and solid tumors.

8 Jul 2011

Common cell pathway could lead to new treatments for autoimmune diseases and cancer

A discovery by University of Alabama at Birmingham researchers about a how a common cell pathway that helps regulate cell survival and production is turned on could lead to new treatments for autoimmune diseases and cancer.

8 Jul 2011

Transplants with half-matched bone marrow or cord blood are comparable to fully matched tissue

Identifying a suitable donor for leukemia and lymphoma patients who need bone marrow transplants may be far easier now that results of two clinical trials show transplant results with half-matched bone marrow or umbilical cord blood are comparable to fully matched tissue, thanks in large part to the availability of effective antirejection drugs and special post-transplant chemotherapy.

8 Jul 2011

Mesenchymal stem cells protect and heal

A stem cell that can morph into a number of different tissues is proving a natural protector, healer and antibiotic maker, researchers at Case Western Reserve University and their peers have found.

8 Jul 2011

AHAF awards 22 new grants to scientists worldwide for innovative vision research

The American Health Assistance Foundation (AHAF), a nonprofit organization with a history of funding cutting-edge research on age-related diseases, announced today that it has awarded 22 new grants totaling nearly $2.2 million to scientists worldwide who are studying glaucoma and macular degeneration. The two conditions are the leading causes of irreversible vision loss and blindness in the U.S.

8 Jul 2011

Half-matched transplants widen donor pool for leukemia and lymphoma

7 Jul 2011

Induced pluripotent cells may make embryonic stem cells unnecessary

For nearly two decades, the medical world and the American public have grappled with the lightning-rod topic of stem cells, in particular the controversy surrounding cells from human embryos. But when researchers four years ago successfully "reprogrammed" adult body cells to become stem cells, some thought the ethical debate was nearly over. Those redirected cells, known as induced pluripotent cells, or iPS cells, show potential as therapy.

6 Jul 2011

Genetic mutations in abnormal bone marrow can predict mortality of MDS patients

For patients with myelodysplastic syndromes (MDS), choosing the appropriate treatment depends heavily on the prognosis. Those patients at the highest risk of dying from their disease are typically offered the most aggressive therapies, while patients at lower risk could live several years with MDS, needing only supportive care or other relatively side-effect free treatments.

1 Jul 2011

Serum-free media with growth factors can improve MSCs' cell fate regulation

Mensenchymal stem cells (MSCs), multipotent cells identified in bone marrow and other tissues, have been shown to be therapeutically effective in the immunosuppression of T-cells, the regeneration of blood vessels, assisting in skin wound healing, and suppressing chronic airway inflammation in some asthma cases.

30 Jun 2011

Molecular radiotherapy offers hope for children with neuroblastoma

A new treatment option may soon be available for children with neuroblastoma according to research published in the July issue of The Journal of Nuclear Medicine.

30 Jun 2011

Researchers, policy experts to examine issue of declining enrollment in clinical trials

Leading researchers and policy experts from across the country will come together June 27 and June 28 at Mount Sinai School of Medicine in New York to examine the issue of declining enrollment in clinical trials.

28 Jun 2011

FDA recommends conservative dosing guidelines for ESAs to treat anemia in patients with CKD

The U.S. Food and Drug Administration today recommended more conservative dosing guidelines for Erythropoiesis-Stimulating Agents (ESAs) when used to treat anemia in patients with chronic kidney disease (CKD) because of the increased risks of cardiovascular events such as stroke, thrombosis, and death.

27 Jun 2011

New model of health care delivery relies on active participation of patients and caregivers

A new model of care developed for patients at the Myeloma Institute for Research and Therapy at the University of Arkansas for Medical Sciences (UAMS) has led to improved patient experience, lower costs and better patient outcomes.

24 Jun 2011

Potential new approach for treating myelofibrosis

A new study conducted by a team of researchers at Boston University School of Medicine (BUSM) sheds light on a possible new approach to treat the bone marrow disease known as myelofibrosis by inhibiting an enzyme that connects extracellular fibers.

24 Jun 2011

FDA grants Orphan Drug Designation for Accentia's Revimmune to treat two autoimmune diseases

Accentia Biopharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to Revimmune, the Company's proprietary system-of-care based on high-dose administration of Cytoxan, for the treatment of two autoimmune disease indications, systemic sclerosis and autoimmune hemolytic anemia.

24 Jun 2011

Telaprevir drug shows promise in curing hepatitis C infection

The drug telaprevir (Incivek) provides a dramatic improvement in the treatment of the most common form of hepatitis C infection, says an international team of investigators led by Dr. Ira M. Jacobson of NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

23 Jun 2011

Experts to focus on Shwachman-Diamond Syndrome at New York Academy of Sciences conference

On June 28-30, 2011, the New York Academy of Sciences will bring together scientists and clinicians from a wide range of subspecialties, in addition to patients and caregivers, to discuss the most important recent advances in our understanding of the clinical features, management, and treatment of Shwachman-Diamond Syndrome (SDS)-a rare disorder involving multiple organ systems and affecting children and young adults.

23 Jun 2011

Twelve institutions receive NPCRC and American Cancer Society grants for palliative care research

The American Cancer Society and the National Palliative Care Research Center (NPCRC) are awarding $2 million in research grants to researchers at 12 institutions for studies aimed at reducing suffering for seriously ill patients and their family caregivers.

22 Jun 2011

Nine young clinical investigators earn recognition from Damon Runyon Cancer Research Foundation

The Damon Runyon Cancer Research Foundation named five new Damon Runyon Clinical Investigators at its spring 2011 Clinical Investigator Award Committee review.

22 Jun 2011

Frequent nighttime home dialysis more effective for patients with kidney failure

Researchers at St. Michael's Hospital have found more evidence of the benefits of home dialysis for patients with kidney failure.

22 Jun 2011

Bone Marrow News and Research

Further Reading

Onconova, SymBio enter commercialization collaboration for rigosertib in Japan and Korea

Common cell pathway could lead to new treatments for autoimmune diseases and cancer

Transplants with half-matched bone marrow or cord blood are comparable to fully matched tissue

Mesenchymal stem cells protect and heal

AHAF awards 22 new grants to scientists worldwide for innovative vision research

Half-matched transplants widen donor pool for leukemia and lymphoma

Induced pluripotent cells may make embryonic stem cells unnecessary

Genetic mutations in abnormal bone marrow can predict mortality of MDS patients

Serum-free media with growth factors can improve MSCs' cell fate regulation

Molecular radiotherapy offers hope for children with neuroblastoma

Researchers, policy experts to examine issue of declining enrollment in clinical trials

FDA recommends conservative dosing guidelines for ESAs to treat anemia in patients with CKD

New model of health care delivery relies on active participation of patients and caregivers

Potential new approach for treating myelofibrosis

FDA grants Orphan Drug Designation for Accentia's Revimmune to treat two autoimmune diseases

Telaprevir drug shows promise in curing hepatitis C infection

Experts to focus on Shwachman-Diamond Syndrome at New York Academy of Sciences conference

Twelve institutions receive NPCRC and American Cancer Society grants for palliative care research

Nine young clinical investigators earn recognition from Damon Runyon Cancer Research Foundation

Frequent nighttime home dialysis more effective for patients with kidney failure

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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