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Loss of SKIP sensitizes cancer cells to apoptotic effects of DNA damage-inducing anticancer drugs

When cells find themselves in a tight spot, the cell cycle regulator p21 halts the cell cycle, buying cells time to repair the damage, or if all else fails, to initiate programmed cell death. In contrast to other stress-induced genes, which dispense with the regular transcriptional entourage, p21Cip1 still requires SKIP, a transcription elongation factor that also helps with the editing of transcripts, to be expressed, found researchers at the Salk Institute for Biological Studies.

2 Apr 2011

LCA calls for comprehensive plan of action to reduce lung cancer mortality

Lung Cancer Alliance called again today for a comprehensive plan of action that will make reducing lung cancer mortality a public health priority.

2 Apr 2011

Colorectal cancer screening vital for prevention and early detection

We're all familiar with messages like this one – "men and women aged 50 and older should have regular colorectal cancer screening tests." We read this message in our community newspapers and hear it on television and radio. Why is there so much media attention on colorectal cancer screening? Well, here's a message you might not have seen: over the last decade, in part due to increased screening, rates of new cases and deaths from colorectal cancer have been on the decline.

1 Apr 2011

Aberrant DNA methylation may initiate cancer development

Cells control which genes they express by multiple mechanisms, one of which is the direct modification of DNA with small molecules. Methylation of genes effectively silences them, and excess DNA methylation, particularly of genes that control the cell cycle, is known to promote cancer formation.

1 Apr 2011

Neogenix Oncology to present laboratory studies of NEO-101 at AACR Annual Meeting

Neogenix Oncology, Inc. announced today that members of its scientific staff will present laboratory studies of NEO-101, a novel monoclonal antibody in development to diagnose and treat pancreatic and colorectal cancers.

1 Apr 2011

FDA approves Medtronic's InterStim Therapy to improve bowel control

Medtronic, Inc. today announced U.S. Food and Drug Administration approval of InterStim Therapy for Bowel Control. InterStim Therapy, previously available to treat the symptoms of overactive bladder and non-obstructive urinary retention, is now also approved for the treatment of chronic fecal incontinence in patients who have failed or are not candidates for more conservative treatments.

1 Apr 2011

Experts discuss about need for national colorectal cancer screening program at Capitol Hill

On Capitol Hill today, colorectal cancer experts and advocates will gather to promote the establishment of a national colorectal cancer screening program in an effort to save lives.

From Evident Corporation - Life Sciences 31 Mar 2011

Basic Yellow 1 dye extends lifespan in healthy nematodes, slows Alzheimer's disease-like pathology in worms

Basic Yellow 1, a dye used in neuroscience laboratories around the world to detect damaged protein in Alzheimer's disease, is a wonder drug for nematode worms. In a study appearing in the March 30, online edition of Nature, the dye, also known as Thioflavin T, (ThT) extended lifespan in healthy nematode worms by more than 50 percent and slowed the disease process in worms bred to mimic aspects of Alzheimer's.

31 Mar 2011

CCAC National Survey finds 82% of Canadians with cancer

The Colorectal Cancer Association of Canada today announced findings from the Weighing Quality of Life in Cancer National Survey showing that an alarming 82 per cent of Canadians have been touched closely by cancer and have had a close friend or family member battle cancer, or have done so themselves.

31 Mar 2011

New system can improve patient adherence to colonoscopy recommendations, reduce disparities

The simple practice of letters and a telephone call to patients who are due for a colonoscopy significantly improves adherence to endoscopic follow-up recommendations, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association Institute.

30 Mar 2011

SHMT1 gene and folate deficiency increase risk for colon cancer

Offering a likely insight into how such cancers develop in humans - Cornell University researchers report they have identified a gene that increases the risk for colon cancer in laboratory mice when the animals' diets are deficient in folate.

30 Mar 2011

Study: Y-90 radioembolization is a safe treatment for patients with liver cancer

Interventional radiologists have been the leaders in the use of intra-arterial yttrium-90 radioembolization, since its introduction in 2000, to treat liver cancer.

29 Mar 2011

Inflammatory bowel disease in children - Delays in diagnosis common

Once a medical rarity in children, inflammatory bowel disease today is increasingly common in kids, but many of them may not be diagnosed in a timely manner, according to experts from the Pediatric Inflammatory Bowel Disease Center at Johns Hopkins Children’s Center.

28 Mar 2011

Everist Genomics announces global launch of OncoDefender-CRC colorectal cancer assay

Everist Genomics today announced the worldwide commercial availability of its OncoDefender-CRC colorectal cancer assay, the first and only molecular prognostic test capable of accurately predicting the risk of recurrence of cancer in patients previously treated with surgical resection of a Stage I/II colon cancer tumor or Stage I rectal cancer tumor.

28 Mar 2011

ALCMI launches new CASTLE study to treat lung cancer

The Addario Lung Cancer Medical Institute today announced the enrollment of the initial subjects into its inaugural clinical trial known as CASTLE, targeting 250 subjects over two years among academic and community medical centers in the United States.

28 Mar 2011

People living at high altitudes have lower chance of dying from heart disease

In one of the most comprehensive studies of its kind, researchers at the University of Colorado School of Medicine in partnership with the Harvard School of Global Health have found that people living at higher altitudes have a lower chance of dying from ischemic heart disease and tend to live longer than others.

28 Mar 2011

Researchers identify enzyme biomarker that can diagnose early colon cancer

A research team at the University of Colorado Cancer Center has identified an enzyme that could be used to diagnose colon cancer earlier. It is possible that this enzyme also could be a key to stopping the cancer.

28 Mar 2011

Smart Medical to customize NaviAid External Channel Device to suit Crospon's EndoFLIP imaging catheter

Medical device developers, Crospon, based in Ireland and Smart Medical Systems based in Ra'anana, Israel today announced that they have signed a collaborative agreement whereby Smart Medical will produce a custom version of their NaviAid™ external channel endoscope accessory for Crospon, to permit deployment and positioning of Crospon's EndoFLIP™ imaging catheter.

25 Mar 2011

Longer Looks: Behind the hospital money curtain; Medical data breaches

Think you would stick to a diet if someone paid you for it? Would you be more likely to exercise if you were fined each time you bailed on your scheduled workout? Research in recent years suggests—and a handful of new businesses are betting—that you might.

25 Mar 2011

Clinical trial to determine whether Crestor can prevent new colon tumors after surgery

Christiana Care Health System's Helen F. Graham Cancer Center is leading a national clinical trial to determine if Crestor, a cholesterol-lowering drug, can prevent new colon tumors from forming after colon cancer surgery.

25 Mar 2011

Colon News and Research

Loss of SKIP sensitizes cancer cells to apoptotic effects of DNA damage-inducing anticancer drugs

LCA calls for comprehensive plan of action to reduce lung cancer mortality

Colorectal cancer screening vital for prevention and early detection

Aberrant DNA methylation may initiate cancer development

Neogenix Oncology to present laboratory studies of NEO-101 at AACR Annual Meeting

FDA approves Medtronic's InterStim Therapy to improve bowel control

Experts discuss about need for national colorectal cancer screening program at Capitol Hill

Basic Yellow 1 dye extends lifespan in healthy nematodes, slows Alzheimer's disease-like pathology in worms

CCAC National Survey finds 82% of Canadians with cancer

New system can improve patient adherence to colonoscopy recommendations, reduce disparities

SHMT1 gene and folate deficiency increase risk for colon cancer

Study: Y-90 radioembolization is a safe treatment for patients with liver cancer

Inflammatory bowel disease in children - Delays in diagnosis common

Everist Genomics announces global launch of OncoDefender-CRC colorectal cancer assay

ALCMI launches new CASTLE study to treat lung cancer

People living at high altitudes have lower chance of dying from heart disease

Researchers identify enzyme biomarker that can diagnose early colon cancer

Smart Medical to customize NaviAid External Channel Device to suit Crospon's EndoFLIP imaging catheter

Longer Looks: Behind the hospital money curtain; Medical data breaches

Clinical trial to determine whether Crestor can prevent new colon tumors after surgery

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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