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Women to use her mother’s womb in Australian medical first transplant

A Victorian woman will be the first Australian to use her own mother’s womb after it has been transplanted into her. Intensive care nurse Melinda Arnold, 34, will undergo a womb transplant after her mother, Denise Allen, agreed to donate the organ to her. Mrs. Arnold, who was born without a womb but with ovaries that produce eggs, twice tried unsuccessfully to use her mother as a surrogate and adoption attempts also failed.

17 Oct 2011

Surgery may be effective in difficult-to-treat epilepsy cases

A study published this week in the journal the Lancet involved 615 patients who were suffering from refractory focal epilepsy, a type that has proved difficult to treat, even with multiple medications.

17 Oct 2011

Gut bacteria shown to affect statin efficacy in some people

The team led by a Duke University scientist has identified three bile acids produced by gut bacteria that were evident in people who responded well to a common cholesterol-lowering drug called simvastatin. The finding, published Oct. 13, 2011, in PLoS One, demonstrates how gut bacteria can cause inherent differences in the way people digest, metabolize and benefit from substances such as drugs.

17 Oct 2011

Laws may be modified for faster approvals of medical devices

Three U.S. senators seeking to speed up review times for medical devices have proposed two new bills for advisers to the Food and Drug Administration (FDA). The measure would reverse 2007 legislation that barred experts who had financial ties to a company or its competitor from serving on an advisory panel without a waiver. There is also a limit on the number of waivers that keeps decreasing.

16 Oct 2011

New book investigates what fuels the passion for science

On April 8, 1982, alone in a laboratory, chemist Dan Shechtman looked through an electron microscope and saw an impossible pattern. He had discovered quasicrystals. But his groundbreaking findings were rejected, even mocked, by the scientific establishment for years.

15 Oct 2011

Johns Hopkins Brain Science Institute organizes Drug Discovery in Academia symposium

A symposium to be hosted by the Johns Hopkins Brain Science Institute (BSi) on Oct. 18 at the Baltimore Convention Center will bring together the pharmaceutical industry and academic-based research institutions with the common goal of exploring how the two can best work together to enhance and facilitate the discovery of new drugs.

15 Oct 2011

UEI tool could allow doctors to deliver efficient, timely treatment for Crohn's disease

It's difficult for doctors to tell whether a patient with Crohn's disease has intestinal fibrosis, which requires surgery, or inflammation, which can be treated with medicine. A new imaging method might make that task easier, according to a U-M-led study.

15 Oct 2011

Functional MRI examines brain activation in individuals with low and high LRs to alcohol

A low level of response (LR) to alcohol reflects at least in part a low brain response to alcohol and carries significant risk for the later development of alcoholism. This study used functional magnetic resonance imaging (fMRI) to examine brain activation in individuals with low and high LRs to alcohol while they performed a cognitive task.

15 Oct 2011

MRI scans may become useful tools for assessing cholesterol drugs

MRI scanning could become a powerful new tool for assessing how well cholesterol drugs are working, according to Loyola University Health System cardiologist Binh An P. Phan, MD.

15 Oct 2011

Brain scans can evaluate new treatments for attention deficit disorder

Scientists have developed a way to evaluate new treatments for some forms of attention deficit disorder. Working in mice, researchers at Washington University School of Medicine in St. Louis showed that they can use brain scans to quickly test whether drugs increase levels of a brain chemical known as dopamine.

15 Oct 2011

Viewpoints: 'Killing' Medicaid; medicine for mentally ill; 'outrageous' veto of mammogram bill in Calif.

Even as it vigorously defends the constitutionality of the individual mandate, the Obama administration may be complicit in eviscerating Medicaid - and setting back the broader goal of ensuring that all Americans have access to quality health care.

15 Oct 2011

HHWC medical doctors provide insight into depression

A staggering 230 million antidepressant prescriptions are filled each year. Yet the face of depression does not always fit the mold: a successful career, loving spouse, wonderful children, seemingly good health and finances. From the outside life appears perfect, so why are Americans depressed?

15 Oct 2011

Scientists reveal how resistance to hormone leptin develops

The effects of obesity - both on our bodies and on the health budget - are well known, and now, scientists are getting closer to understanding how the disease progresses, providing clues for future treatments.

15 Oct 2011

Study examines link between alcohol and harm in European countries

A new study examines the impact that the cultural context of drinking may have on the relationship between drinking and harm in several European countries. Results suggest a significant relationship between volume of consumption and risk of experiencing alcohol-related problems in all five countries examined.

15 Oct 2011

ApoPharma receives FDA approval for Ferriprox to treat transfusional iron overload

The U.S. Food and Drug Administration today approved Ferriprox (deferiprone) to treat patients with iron overload due to blood transfusions in patients with thalassemia, a genetic blood disorder that causes anemia, who had an inadequate response to prior chelation therapy.

15 Oct 2011

Barcodes evolving into a broader class of identifiers in new ways

What if you could trace the history of everything you buy back to its origins? Using your smart phone camera, you could learn what factory made the ingredients in your heart medication, what country grew the corn in your breakfast cereal, or even how to recycle the phone. You could follow the whole life cycle of a product and everyone who handled it along the way to ensure that the medicine you're taking isn't counterfeit and the food you're eating is safe.

14 Oct 2011

Emergency grant to end U.S. AIDS drug crisis gets rejected

The Global Fund for AIDS, Tuberculosis and Malaria has notified the AIDS Healthcare Foundation (AHF) that an application it submitted on behalf of the United States for an emergency grant of $50 million to end the ongoing AIDS drug crisis in the U.S. is being rejected because, as one of the wealthiest nations in the world, "the United States is not eligible for funding from the Global Fund."

14 Oct 2011

Researchers identify gut bacteria bile acids linked to effectiveness of statin drugs in lowering cholesterol

Statins can be effective at lowering cholesterol, but they have a perplexing tendency to work for some people and not others. Gut bacteria may be the reason.

14 Oct 2011

Four companies receive NIAID contracts to develop broad-spectrum therapeutics

Four companies are to develop broad-spectrum therapeutics-antibiotics, antivirals and an antitoxin-to prevent or treat diseases caused by multiple types of bacteria or viruses, under contracts awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

14 Oct 2011

IRMS tracks course of designer 'legal high' drugs manufacture

Urgently needed tests which could help identify the manufacturers of designer 'legal high' drugs are being developed in research led at the University of Strathclyde in Glasgow.

14 Oct 2011