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New York Times 'Small Fixes' section examines multiple low-cost interventions for global health problems

The New York Times on Monday published a special section, titled "Small Fixes," containing several articles examining how low-cost innovations could help save thousands of lives.

28 Sep 2011

UCI professor wins Presidential Early Career Award for Scientists & Engineers

Rommie Amaro, UC Irvine assistant professor of pharmaceutical sciences and computer science, has been selected by President Obama for the Presidential Early Career Award for Scientists & Engineers.

28 Sep 2011

More predictability in the chaos of infectious Chagas disease transmission

Despite what Hollywood would have you believe, not all epidemics involve people suffering from zombie-like symptoms--some can only be uncovered through door-to-door epidemiology and advanced mathematics.

28 Sep 2011

Benefits and harms vary among atypical antipsychotics for off-label use

A review of previous studies suggests that even though atypical antipsychotic medications are commonly used for off-label conditions such as behavioral symptoms of dementia, anxiety, and obsessive-compulsive disorder, these medications are effective for only a few off-label conditions, and that the benefits and harms of these medications for these uses vary, according to an article in the September 28 issue of JAMA.

28 Sep 2011

Microbiologist offers advice to guard against coming down with the flu

October marks the beginning of flu season, and once again, health care professionals are exhorting people to get a flu shot. Microbiologist John Tudor, Ph.D., professor of biology at Saint Joseph's University in Philadelphia, agrees that it's time to roll up our sleeves and offer up our arms for the vaccination.

28 Sep 2011

DMARDs appear to be more effective for children with arthritis

Medications known as disease-modifying anti-rheumatic drugs, or DMARDs, appear to be more effective than other treatments for children with arthritis, but there is not enough evidence to support one kind of DMARD over another, according to a new report from HHS' Agency for Healthcare Research and Quality.

28 Sep 2011

Healthcare becoming an overdrive model feel half of the primary physicians

In a new poll of primary care physicians, nearly half of them said their patients received too much medical care and more than a quarter said they were practicing more aggressively than they'd like to. This could mean ordering more tests, prescribing more drugs or diagnosing people with diseases, although they would never have experienced any symptoms. On the other hand, just six percent of doctors believed their patients were getting too little care.

27 Sep 2011

Low vitamin B12 raises risk of dementia in the elderly: Study

According to a latest study the elderly with low levels of vitamin B12 in their blood may be more likely to develop problems with their thinking skills and have more brain shrinkage. The study points to a link between low B12 and early cognitive decline, a condition that often leads to dementia. Previous research has found that those people with high levels of vitamin B12 in their blood have lower levels of an amino acid called homocysteine, which some studies have linked to an increased risk of Alzheimer's disease, memory loss, and stroke.

27 Sep 2011

Afraxis to participate in NIH's Therapeutics for Rare and Neglected Disease Program

Afraxis, a San Diego-based biotechnology company developing drugs to treat rare genetic diseases through the modulation of p21-activated kinase (PAK), announced today that it has been selected to participate in the National Institutes of Health's (NIH) Therapeutics for Rare and Neglected Disease (TRND) Program.

27 Sep 2011

Lead compound activates infection-fighting REDD1 protein and kills flu strain

A compound tested by UT Southwestern Medical Center investigators destroys several viruses, including the deadly Spanish flu that killed an estimated 30 million people in the worldwide pandemic of 1918.

27 Sep 2011

Researchers modify HIV in a way that makes it no longer able to suppress immune system

Researchers at Johns Hopkins have modified HIV in a way that makes it no longer able to suppress the immune system. Their work, they say in a report published online September 19 in the journal Blood, could remove a major hurdle in HIV vaccine development and lead to new treatments.

27 Sep 2011

Eating blueberries may inhibit breast cancer tumor growth

Eating blueberries may inhibit breast cancer tumor growth, according to a recent study by researchers at the City of Hope in Los Angeles that is published in the October 2011 issue of The Journal Of Nutrition and featured in the September issue of Food Nutrition & Science.

27 Sep 2011

Research roundup: Widows and medical spending; disparities in heart care, hospital deaths

The authors write: "We find that out-of-pocket medical spending is approximately 29 percent higher when an individual becomes widowed, a large portion of which is spending on nursing homes. Our results suggest a substantial role of living arrangements in out-of-pocket medical spending; however, our estimates combined with differences in rates of widowhood across gender suggest that marital status can explain only one third of the gender difference in total out-of-pocket medical spending, leaving a large portion unexplained.

27 Sep 2011

GAO report: More oversight needed on program that gives safety net providers discounts on outpatient drugs

Under this program, known as the 340 B program, drugmakers provide discounts to community health centers and other health care providers that treat vulnerable populations in exchange for having their drugs covered by Medicaid.

27 Sep 2011

UCSF, QuantiaMD develop new DiabetesIQ mobile phone app

A new interactive mobile phone app called DiabetesIQ, released this week, challenges people to test their knowledge of diabetes and to compete with one another as they learn about the complexities of the disease, which affects more than 25 million Americans, including 4 million Californians.

27 Sep 2011

Zoledronic acid may extend survival in older breast cancer patients

A drug used to protect bone may extend survival in older breast cancer patients, according to researchers at the Universities of Sheffield and Leeds.

27 Sep 2011

Viewpoints: LA Times wants solutions from GOP candidates; WSJ finds worrisome census numbers

We've now seen three full-dress debates among the Republican politicians who want to be the next president of the United States, and here's what we've learned: They all believe taxes are too high, even though federal taxes are lower as a percentage of the U.S. economy than any time in the last 60 years. They all believe onerous environmental regulations are preventing economic recovery, though few economists would agree.

27 Sep 2011

Alnylam commences ALN-PCS Phase I trial in severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-PCS, an RNAi therapeutic targeting proprotein convertase subtilisin/kexin type 9, or PCSK9, for the treatment of severe hypercholesterolemia.

27 Sep 2011

Roundup: Patient dies after medical error during Calif. nurses strike; grocery workers ratify contract that had partially hinged on health care

Veteran nurses locked out of Alta Bates Summit Medical Center in Oakland said Sunday that the death of a patient due to a medical error by a replacement worker wouldn't have happened if they had been allowed to do their jobs. The hospital's management countered that it was a freak accident that could have happened at any time -- with or without the replacement nurses. At the center of the dispute is a cancer patient, a woman who has not been identified but whose tragic death on Saturday has inflamed an already tense labor dispute.

27 Sep 2011

Smaller and faster clinical drug trials could improve gains in cancer survival

With the advent of personalised medicine, gains in cancer survival over the long term could be improved by running smaller, faster trials with less stringent evidence criteria, a researcher told the 2011 European Multidisciplinary Cancer Congress.

26 Sep 2011