Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Computerized decision support tool can assist physicians in prescribing stroke prevention therapy

Physician-researchers in the College of Medicine at the University of Cincinnati have developed a computerized decision support tool that uses a combination of patient information and characteristics to assist physicians and patients with decisions about blood thinning treatment to prevent strokes in individuals with atrial fibrillation.

12 May 2016

Daiichi buys Japanese rights to CTL’s innovative cardiac regeneration medicine, Heartcel

Cell Therapy Ltd. today announced the granting of the Japan license for its innovative cardiac regeneration medicine, Heartcel™ (immuno-modulatory progenitor [iMP] cells) to Daiichi Sankyo.

11 May 2016

Moderate sedation leads to better clinical outcomes than general anesthesia for TAVR patients

A new study finds the use of moderate sedation, in which patients do not need a breathing tube, leads to better clinical outcomes as compared to general anesthesia for patients undergoing transcatheter aortic valve replacement (TAVR).

9 May 2016

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

Patients with atrial fibrillation (AF), a rapid irregular heartbeat caused by pooling blood in the heart which can lead to heart failure and stroke, are often treated with an ablation, a minimally invasive procedure used to remove the tissue which causes the pooled blood.

9 May 2016

Drinking tart Montmorency cherry juice can reduce early signs of hypertension

Drinking tart Montmorency cherry juice significantly reduces high blood pressure at a level comparable to that achieved by medication, according to new research from Northumbria University, Newcastle.

6 May 2016

Long-term Warfarin use may increase dementia rates in AF patients

A new study of more than 10,000 patients treated long term with the blood thinner, Warfarin, reveals higher rates of dementia for patients with atrial fibrillation versus non-AF patients

5 May 2016

Study shows short-term statin treatment does not benefit heart surgery patients

Giving daily doses of statins for a few days before and after heart surgery does not prevent heart muscle damage or the development of atrial fibrillation (AF), according to an international clinical trial led by the University of Oxford and funded by the British Heart Foundation.

5 May 2016

LifeBridge Health study to explore potential benefits of wireless heart monitoring system

The LifeBridge Health Cardiovascular Institute has launched a pilot study to evaluate the potential benefits of a wireless heart monitoring system for patients with moderate to severe heart failure. The system tracks weight, blood pressure and other measures, and automatically sends the information to doctors and staff at the Cardiovascular Institute. The study is looking at whether this approach, designed to be simple and easy-to-use, can result in better outcomes for patients with heart failure.

5 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

Researchers discover critical new mechanism for genesis of heart failure

A weak heart is unable to pump an adequate amount of blood around the body. In Germany, this condition is now the commonest reason for patients to be admitted to hospital.

4 May 2016

Advances in telemedicine: an interview with Dr Ameet Bakhai

Telemedicine is the art of improving patient care via managing data remotely, and in this spirit one of the earliest examples often not considered in this category, would be the permanent pacemaker, first implanted into a human being in 1958.

2 May 2016

Novel gene therapy can treat pulmonary hypertension linked with heart failure

Scientists have used a novel gene therapy to halt the progression of pulmonary hypertension, a form of high blood pressure in the lung blood vessels that is linked to heart failure, according to a study led by Roger J. Hajjar, MD, Professor of Medicine and Director of the Cardiovascular Research Center at the Icahn School of Medicine at Mount Sinai.

30 Apr 2016

Clinicians describe placement of first implantable hemodynamic monitor in single ventricle Fontan anatomy

While the Fontan procedure has improved the short- and mid-term outcomes for patients born with single ventricle anatomy, long-term complications of Fontan circulation include heart failure. These complications are thought to be secondary to elevated central venous pressure, chronic venous congestion and low cardiac output.

29 Apr 2016

Review focuses on autologous cell therapy that can be applied to cardiac surgery

The combination of cell and gene therapy is rapidly raising clinical interest, although their combination has been under investigation for several decades. This is mainly due to the availability and feasibility of clinically relevant gene delivery options. This review focuses on cell therapies for heart failure and their use combined with cardiac surgery as well as with gene therapy.

27 Apr 2016

Endocrine Society urges physicians to increase screening for primary aldosteronism

The Endocrine Society today issued a Clinical Practice Guideline calling on physicians to ramp up screening for primary aldosteronism, a common cause of high blood pressure.

27 Apr 2016

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen.

26 Apr 2016

Testosterone may lead to greater heart attack risk in men than women

Testosterone might be involved in explaining why men have a greater risk of heart attacks than women of similar age, according to a study funded by the British Heart Foundation and the Biotechnology and Biological Sciences Research Council. The findings, published in the journal Scientific Reports, could lead to new therapies to help reduce heart attack risk.

21 Apr 2016

Herceptin drugs for breast cancer linked with increased risk of congestive heart failure

Breast cancer patients undergoing treatment with trastuzumab-containing regimens should be monitored for heart damage regardless of age. This is among the findings of a new study from the Peter Munk Cardiac Centre, the Institute for Clinical Evaluative Sciences (ICES) and the Ted Rogers Centre for Heart Research, University Health Network.

20 Apr 2016

Existing cancer drugs may be able to help people with enlarged heart cells

UT Southwestern Medical Center cardiology researchers have identified molecular ties between the growth of cancer cells and heart cells that suggest existing cancer drugs may be able to help those with enlarged heart cells -- a condition that can lead to heart attacks and stroke.

18 Apr 2016

Inserm study reveals potential of secondary system to improve heart function

Heart failure affects over one million people in France. Although the blood system is the first to have been explored for the purpose of improving heart function, a study by Inserm has revealed the potential of a secondary system that had previously received scant attention.

13 Apr 2016

Heart Failure News and Research

Further Reading

Computerized decision support tool can assist physicians in prescribing stroke prevention therapy

Daiichi buys Japanese rights to CTL’s innovative cardiac regeneration medicine, Heartcel

Moderate sedation leads to better clinical outcomes than general anesthesia for TAVR patients

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

Drinking tart Montmorency cherry juice can reduce early signs of hypertension

Long-term Warfarin use may increase dementia rates in AF patients

Study shows short-term statin treatment does not benefit heart surgery patients

LifeBridge Health study to explore potential benefits of wireless heart monitoring system

Bayer-new phase 3 liver cancer data

Researchers discover critical new mechanism for genesis of heart failure

Advances in telemedicine: an interview with Dr Ameet Bakhai

Novel gene therapy can treat pulmonary hypertension linked with heart failure

Clinicians describe placement of first implantable hemodynamic monitor in single ventricle Fontan anatomy

Review focuses on autologous cell therapy that can be applied to cardiac surgery

Endocrine Society urges physicians to increase screening for primary aldosteronism

Hydrocortisone drug can also prevent lung damage in premature babies

Testosterone may lead to greater heart attack risk in men than women

Herceptin drugs for breast cancer linked with increased risk of congestive heart failure

Existing cancer drugs may be able to help people with enlarged heart cells

Inserm study reveals potential of secondary system to improve heart function

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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