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Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer.

21 May 2021

Tobacco smoke exposure in utero and during early childhood can affect children's lung function

Environmental tobacco smoke exposure in utero and during early childhood - especially secondhand smoke - is associated with decreased childhood lung function, according to research presented at the ATS 2021 International Conference.

20 May 2021

Extensive cancer research data to be presented at the 2021 ASCO Annual Meeting

Rutgers Cancer Institute of New Jersey, a leader in cutting-edge clinical trials and health outcomes analyses and a designated Comprehensive Cancer Center by the National Cancer Institute, together with RWJBarnabas Health, today announced that data from its cancer clinical research program will be presented at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, to be held virtually from June 4-8.

20 May 2021

Study could serve as guidepost for developing new therapies for Alzheimer's disease

In a major breakthrough, researchers at Massachusetts General Hospital (MGH) have discovered how amyloid beta--the neurotoxin believed to be at the root of Alzheimer's disease (AD)--forms in axons and related structures that connect neurons in the brain, where it causes the most damage.

20 May 2021

Philly CEAL team receives NIH grant to extend COVID-19 outreach

José A. Bauermeister, PhD, and Antonia M. Villarruel, PhD, are leading one of 10 new research teams from across the country that received National Institutes of Health (NIH) grants totaling $14 million to extend the reach of the NIH's Community Engagement Alliance (CEAL) Against COVID-19 Disparities.

20 May 2021

Study addresses “leaky pipeline” that prevents Black medical students in reaching their residency goals

Self-affirmation, the practice of reflecting upon one's most important values, can aid Black medical students in reaching their residency goals. But conversely, it can lead to the perception that they are less qualified for a prestigious residency than their peers.

20 May 2021

Study: Multiple combinations of activities reduced risk of early death by 30%

A new study from Columbia University and an international team of researchers identifies multiple ways to achieve the same health benefits from exercise--as long as the exercise "cocktail" includes plenty of light physical activity.

19 May 2021

Protein intake is more important than protein source to gain muscle strength and mass

Protein intake is more important than protein source if the goal is to gain muscle strength and mass.

19 May 2021

A study reports the first case of an upper extremity deep vein thrombosis (DVT) recurrence due to COVID-19 infection

Researchers have reported the first case of COVID-19 triggering a rare occurrence of potentially severe blood clots forming in the arms.

19 May 2021

NYITCOM researcher receives NIH grant to explore effect of stress on clinical depression

A researcher at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) has secured a grant from the National Institutes of Health (NIH) to study how certain brain cells respond to chronic stress.

19 May 2021

Despite socioeconomic status, racial and ethnic populations endure worse COVID-19 outcomes

A research team, led by the University of Minnesota Medical School, found that regardless of socioeconomic status, Twin Cities residents of underrepresented racial and ethnic backgrounds endure worse COVID-19 outcomes compared to people who are white.

18 May 2021

Preventive interventions in young people can prevent certain mental health disorders

Offering interventions to young people in the general community can prevent the emergence of certain mental health disorders, according to the first comprehensive systematic review to address this question.

18 May 2021

Medications commonly prescribed for schizophrenia linked to cognitive impairment

Writing in the May 14, 2021 issue of The American Journal of Psychiatry, a multi-institution team of scientists led by researchers at University of California San Diego School of Medicine report that medications commonly prescribed to reduce the severity of physical and mental health symptoms associated with schizophrenia may have a cumulative effect of worsening cognitive function in patients.

18 May 2021

Charles Fracchia selected for DARPA ISAT Study Group

Dotmatics today announced that the US Defense Advanced Research Projects Agency has named Charles Fracchia to its ISAT Study Group.

18 May 2021

COVID-19 pandemic causes disproportionate rise in cardiovascular deaths among racial, ethnic minorities

In the early months of the COVID-19 pandemic, the United States experienced higher rates of heart disease and cerebrovascular disease deaths, relative to the corresponding months the previous year.

18 May 2021

Researchers link “genetic signatures” of bacteria in the human gut to multiple diseases

We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome.

18 May 2021

Study: No major difference in mortality between patients treated with drug-coated and non-drug-coated devices

Peripheral artery disease (PAD), or blockages in the arteries outside of the heart, affects more than 200 million people worldwide and 12.5 million people in the United States. Patients with this circulatory disorder may develop severe leg pain or unhealing wounds that require a minimally invasive revascularization procedure to open the blood vessels to improve blood flow.

18 May 2021

A promising drug delivery system for therapeutics that shut down harmful genes

Viruses attack the body by sending their genetic code -- DNA and RNA -- into cells and multiplying. A promising class of therapeutics that uses synthetic nucleic acids to target and shut down specific, harmful genes and prevent viruses from spreading is gaining steam.

18 May 2021

Sotagliflozin reduces adverse cardiovascular events across patients with diabetes, heart failure

Patients with both diabetes and heart failure who were treated with sotagliflozin, a novel investigational drug for diabetes, for a median of nine to 16 months experienced reductions of 22% to 43% in the risk of death or worsening heart failure compared with similar patients who were treated with a placebo

18 May 2021

Cancer patients without health insurance had significantly worse survival than Medicare beneficiaries

MUSC Hollings Cancer Center lung cancer researcher Gerard Silvestri, M.D., found that a lack of insurance leads to worse cancer survival than for those with Medicare, in a paper published in the May issue of Health Affairs.

17 May 2021

Medical School News and Research

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Tobacco smoke exposure in utero and during early childhood can affect children's lung function

Extensive cancer research data to be presented at the 2021 ASCO Annual Meeting

Study could serve as guidepost for developing new therapies for Alzheimer's disease

Philly CEAL team receives NIH grant to extend COVID-19 outreach

Study addresses “leaky pipeline” that prevents Black medical students in reaching their residency goals

Study: Multiple combinations of activities reduced risk of early death by 30%

Protein intake is more important than protein source to gain muscle strength and mass

A study reports the first case of an upper extremity deep vein thrombosis (DVT) recurrence due to COVID-19 infection

NYITCOM researcher receives NIH grant to explore effect of stress on clinical depression

Despite socioeconomic status, racial and ethnic populations endure worse COVID-19 outcomes

Preventive interventions in young people can prevent certain mental health disorders

Medications commonly prescribed for schizophrenia linked to cognitive impairment

Charles Fracchia selected for DARPA ISAT Study Group

COVID-19 pandemic causes disproportionate rise in cardiovascular deaths among racial, ethnic minorities

Researchers link “genetic signatures” of bacteria in the human gut to multiple diseases

Study: No major difference in mortality between patients treated with drug-coated and non-drug-coated devices

A promising drug delivery system for therapeutics that shut down harmful genes

Sotagliflozin reduces adverse cardiovascular events across patients with diabetes, heart failure

Cancer patients without health insurance had significantly worse survival than Medicare beneficiaries

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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