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Microbes within gut may hold key to one cause of obesity

In terms of diversity and sheer numbers, the microbes occupying the human gut easily dwarf the billions of people inhabiting the Earth.

19 Jan 2009

Genetic testing not cost-effective in guiding initial dosing of blood-thinner warfarin

New analyses led by the University of Cincinnati (UC) show that genetic testing used to guide initial dosing of the blood-thinner warfarin may not be cost-effective for typical patients with atrial fibrillation but may be for patients at higher risk for major bleeding.

19 Jan 2009

Arpida receives FDA complete response letter for Iclaprim

Arpida Ltd. has announced that it has received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) regarding its New Drug Application (NDA) for intravenous iclaprim for the treatment of complicated skin and skin structure infections (cSSSI).

19 Jan 2009

CSL Behring receives FDA approval of RiaSTAP

CSL Behring announced today that the U.S. Food and Drug Administration (FDA) has granted marketing approval for RiaSTAP(TM), the first and only treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.

19 Jan 2009

Three new genetic variations that increase the risk of obesity

The gene variant most strongly associated with childhood obesity and adult morbid obesity in the study is located near the PTER gene, the function of which is not known. This variant is estimated to account for up to a third of all childhood obesity, and a fifth of all cases of adult obesity.

19 Jan 2009

Salmonella prompts recall of Kellogg's snacks

Food and Drug Administration (FDA) officials in the United States have confirmed the presence of salmonella in a popular snack made by food giant Kellogg.

19 Jan 2009

Coca-Cola accused of outright fraud

Soft drink giant Coca-Cola has been accused of making deceptive and unsubstantiated health claims about its Vitaminwater beverages.

19 Jan 2009

Calorie info on menus for Brits in battle of the bulge

A scheme to provide diners in Britain with calorie information on menus is set to be introduced there this summer.

19 Jan 2009

Nanotechnology safety high on Congress' priority list

The House Science and Technology Committee has introduced legislation that highlights the growing attention on Capitol Hill to the need to strengthen federal efforts to learn more about the potential environmental, health and safety (EHS) risks posed by engineered nanomaterials.

19 Jan 2009

European viral epidemic linked to global warming

An epidemic of the viral disease nephropathia epidemica (NE) has been linked to increases in the vole population caused by hotter summers, milder winters and increased seedcrop production by broadleaf trees.

19 Jan 2009

Savella - Fibromyalgia treatment approved by FDA

Forest Laboratories, Inc. and Cypress Bioscience, Inc. have announced that Savella (milnacipran HCl), a selective serotonin and norepinephrine dual reuptake inhibitor, was approved by the U.S. Food and Drug Administration (FDA) for the management of fibromyalgia.

19 Jan 2009

New FDA guidelines for foods and feeds

The U.S. Food and Drug Administration has issued three guidances designed to help ensure the safety of FDA-regulated products in the supply chain.

19 Jan 2009

FDA issues final guidance on genetically engineered animal regulation

The U.S. Food and Drug Administration has issued a final guidance for industry on the regulation of genetically engineered (GE) animals under the new animal drug provisions of the Federal Food, Drug and Cosmetic Act (FFDCA).

19 Jan 2009

Eli Lilly to pay $1.415 billion for off-label promotion of Zyprexa

American pharmaceutical giant Eli Lilly and Company today agreed to plead guilty and pay $1.415 billion for promoting its drug Zyprexa for uses not approved by the Food and Drug Administration (FDA), the Department of Justice announced today.

19 Jan 2009

FDA approves RiaSTAP for bleeding in patients with congenital fibrinogen deficiency

The U.S. Food and Drug Administration has licensed RiaSTAP, an orphan drug for the treatment of bleeding in patients with a rare genetic defect known as congenital fibrinogen deficiency. Without treatment, these patients are at risk of potentially life-threatening bleeding.

18 Jan 2009

Too much coffee can lead to hallucinations

According to a study by researchers at Durham University people with a higher caffeine intake, from coffee, tea and caffeinated energy drinks, are more likely to experience hallucinatory experiences such as hearing voices and seeing things that are not there.

18 Jan 2009

FDA issues complete response letter for SAPHRIS (asenapine) sublingual tablets in acute treatment of schizophrenia and bipolar disorder

Schering-Plough Corporation has announced that the U.S. Food and Drug Administration (FDA) has issued a complete response letter for SAPHRIS (asenapine) sublingual tablets in the acute treatment of schizophrenia in adults and in the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults as monotherapy.

15 Jan 2009

Odors can alter gene expression in an olfactory neuron

New research from University of California, Davis, shows why a species of tiny worm can learn to ignore an odor – information that could have implications for how human memories are formed.

15 Jan 2009

You may not be what your mother eats

Researchers S. Stanley Young, Ph.D., Assistant Director of the National Institute of Statistical Sciences, Heejung Bang, Ph.D., of Cornell University and Kutluk Oktay. MD, FACOG, Professor of Obstetrics & Gynecology and Director, Division of Reproductive Medicine & Infertility Department of Obstetrics & Gynecology from New York Medical College, wrote a paper, "Cereal-Induced Gender Selection? Most Likely a Multiple Testing False Positive," which has been published in the January 14, 2009 online issue of the Proceedings of the Royal Society B.

15 Jan 2009

New model system may better explain regulation of body weight

A new mathematical model of the physiological regulation of body weight suggests a potential mechanism underlying the difficulty of losing weight, one that includes aspects of two competing hypotheses of weight regulation.

15 Jan 2009