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KAI enters KAI-4169 development and commercialization agreement with Ono

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced the signing of an agreement with Ono Pharmaceutical Co., Ltd. for the development and commercialization in Japan of KAI-4169, KAI's lead product candidate.

15 Sep 2011

CHK Nutrition, NeuroResearch Clinics sign consent to halt sale of unapproved amino-acid products

The U.S. Food and Drug Administration announced that two Minnesota companies have agreed to halt distribution of amino-acid products marketed to treat a number of diseases, until requirements of the Federal Food, Drug, and Cosmetic Act are met.

15 Sep 2011

ODAC recommends ApoPharma's Ferriprox for FDA approval to treat transfusional iron overload

ApoPharma Inc. today announced that the Oncologic Drugs Advisory Committee (ODAC) to the U.S. Food and Drug Administration (FDA) voted 10 - 2 to recommend that the FDA grant accelerated approval of Ferriprox (deferiprone), an oral iron chelator, for the treatment of patients with transfusional iron overload when current chelation therapy is inadequate.

15 Sep 2011

Heart specialists reveal how pacemaker works at the biological level

Heart specialists at Johns Hopkins have figured out how a widely used pacemaker for heart failure, which makes both sides of the heart beat together to pump effectively, works at the biological level.

15 Sep 2011

UIC researchers to conduct study on televised drug commercials

Do pharmaceutical ads educate patients and improve health -- or merely spur drug sales? Researchers at the University of Illinois at Chicago's Institute for Health Research and Policy will conduct the first comprehensive study of televised drug commercials using Nielsen Media Research and health care utilization data.

15 Sep 2011

Patients with hepatitis C may benefit from 24 week telaprevir-based regimen

University of Cincinnati research published in the Sept. 14, 2011, advance online edition of the New England Journal of Medicine shows that patients with hepatitis C who took a combination medication-a telaprevir-based regimen that is commonly used to treat the illness-for 24 weeks were cured.

15 Sep 2011

Rac1 protein triggers growth of long 'legs' that could propel melanoma cells to spread

Cancer Research UK scientists have discovered that a protein called Rac1 prompts pigment cells to sprout long 'legs' that could propel skin cancer cells, allowing them to spread, according to research published in Developmental Cell today.

15 Sep 2011

Researchers discover several chemical compounds against human prion diseases

In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening the door to potential treatments for human prion diseases.

15 Sep 2011

Natural killer white blood cells caught on film

Scientists reveal in more detail than ever before how white blood cells kill diseased tissue using deadly granules, in research published today in PLoS Biology.

14 Sep 2011

DiscoveryBioMed receives NIDDK grant for Cystic Fibrosis Corrector Ligand Drug Discovery program

DiscoveryBioMed, Inc. (DBM), a human cell-based drug discovery company, learned recently that its Cystic Fibrosis Corrector Ligand (CFCL) Drug Discovery program will be funded by the NIH. The two-year award will focus on validation and prioritization of several lead CFCL chemical classes, drugs that correct the most common cystic fibrosis (CF) disease-causing mutation.

14 Sep 2011

Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

Cornell University researchers may have solved a 100-year puzzle: How to safely open and close the blood-brain barrier so that therapies to treat Alzheimer's disease, multiple sclerosis and cancers of the central nervous system might effectively be delivered.

14 Sep 2011

NIH awards Rutgers and UMDNJ $23.2M grant to develop drugs against mustard gas

The National Institutes of Health (NIH) has awarded a five-year $23.2 million grant to a group of investigators at Rutgers University and the University of Medicine and Dentistry of New Jersey (UMDNJ)-Robert Wood Johnson Medical School to continue their research aimed at developing drug products that could be used against chemical warfare agents from a terrorist attack.

14 Sep 2011

FDA grants Orphan Drug Designation for Accentia's Revimmune to prevent GVHD

Accentia Biopharmaceuticals, Inc. and its majority-owned subsidiary, Biovest International, Inc., today jointly announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to Revimmune, the Company's proprietary system-of-care based on high-dose administration of Cytoxan, for the prevention of graft-versus-host disease (GVHD) following bone marrow transplant.

14 Sep 2011

Number of global malaria deaths fell by one-fifth over past decade, RBM report says

Worldwide, the number of malaria deaths has "fallen by a fifth over the past decade, reflecting an influx of funds to fight the disease with better drugs and mosquito nets, Roll Back Malaria (RBM) said" in a report released on Monday, Agence France-Presse reports.

14 Sep 2011

Indian state of Jammu and Kashmir avoids grim AIDS predictions

When the only community health care center providing medical and psychosocial care for people living with HIV/AIDS in India's northernmost state of Jammu and Kashmir "closed down six months ago for lack of patients, it was a sure sign that the north Indian state had beaten back dire forecasts," Inter Press Service reports.

14 Sep 2011

Jefferson neurologist receives Harold G. Wolff Lecture Award for migraine headache model

Michael L. Oshinsky, Ph.D., assistant professor of Neurology at Jefferson Medical College of Thomas Jefferson University, and a member of the Jefferson Headache Center team, was recently named the 2011 Harold G. Wolff Lecture award recipient for creating a new animal model of migraine headache.

14 Sep 2011

Researchers at South Korean lab make advance in fight against neglected tropical diseases

VOA News reports on a scientific breakthrough, which researchers call a "game changer" for developing new drugs, developed at Institut Pasteur Korea [IPK], a South Korean branch of the 124-year-old French research institute that is developing new drugs to combat diseases mainly affecting developing countries, including neglected tropical diseases.

14 Sep 2011

UN report on illicit drug use worldwide

According to a new United Nations report the use of stimulant drugs of abuse like amphetamine, ecstasy and meth is increasing worldwide. The report adds that the growing trade in these illegal drugs and the high profits they bring to criminals are posing an increasing threat to health and security.

14 Sep 2011

Prescription drugs expensive in Australia and likely to increase

According to experts Australians are facing some of the highest ‘out-of-pocket’ costs in the industrialized world for prescription medicines and the problem is likely to worsen

14 Sep 2011

Dementia needs early diagnosis: Report

According to a new report sponsored by Alzheimer’s Disease International, nearly three-quarters of the 36 million people living with dementia have not been diagnosed with it. Experts say the lack of diagnosis has enormous repercussions on early treatment and care, and has a direct impact on the disease’s cost to society.

14 Sep 2011

Drugs News and Research

KAI enters KAI-4169 development and commercialization agreement with Ono

CHK Nutrition, NeuroResearch Clinics sign consent to halt sale of unapproved amino-acid products

ODAC recommends ApoPharma's Ferriprox for FDA approval to treat transfusional iron overload

Heart specialists reveal how pacemaker works at the biological level

UIC researchers to conduct study on televised drug commercials

Patients with hepatitis C may benefit from 24 week telaprevir-based regimen

Rac1 protein triggers growth of long 'legs' that could propel melanoma cells to spread

Researchers discover several chemical compounds against human prion diseases

Natural killer white blood cells caught on film

DiscoveryBioMed receives NIDDK grant for Cystic Fibrosis Corrector Ligand Drug Discovery program

Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

NIH awards Rutgers and UMDNJ $23.2M grant to develop drugs against mustard gas

FDA grants Orphan Drug Designation for Accentia's Revimmune to prevent GVHD

Number of global malaria deaths fell by one-fifth over past decade, RBM report says

Indian state of Jammu and Kashmir avoids grim AIDS predictions

Jefferson neurologist receives Harold G. Wolff Lecture Award for migraine headache model

Researchers at South Korean lab make advance in fight against neglected tropical diseases

UN report on illicit drug use worldwide

Prescription drugs expensive in Australia and likely to increase

Dementia needs early diagnosis: Report

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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