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Why predictive retina models could be the future of IND applications

Discover how retina models are revolutionizing rare disease treatment and accelerating drug development.

From Newcells Biotech 22 Nov 2024

New study unveils why glioblastoma becomes resistant to treatment

A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach that paves the way for more personalized treatment strategies for patients with this deadly brain tumor.

22 Nov 2024

Cetuximab performs better than durvalumab in treating head and neck cancers

Head and neck cancers are the seventh most common type of cancer worldwide, according to the 2020 World Cancer Report. Smokers and drinkers, as well as those with HPV infections, are disproportionately affected.

22 Nov 2024

ESGCT Conference Takeaways: A specialty laboratory perspective

Discover the latest innovations in cell and gene therapy via Cerba Research's highlights of ESGCT.

From Cerba Research 22 Nov 2024

Mapping human biology: Human Cell Atlas leads a new era in precision medicine

The Human Cell Atlas project maps human cells to understand biology, address global health disparities, and advance personalized medicine through ethical and inclusive research practices.

21 Nov 2024

SCimilarity revolutionizes single-cell data analysis with rapid cross-tissue comparisons

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables scalable discovery of shared cellular states and biological insights across the Human Cell Atlas.

21 Nov 2024

AI models redefine TIL scoring in breast cancer but face challenges in real-world validation

AI models analyzing tumor-infiltrating lymphocytes show promise in predicting outcomes for triple-negative breast cancer, but external validation reveals critical performance gaps.

21 Nov 2024

Study suggests a key to kick-start the heart's own repair mechanism

After severe heart failure, the ability of the heart to heal by forming new cells is very low. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart.

21 Nov 2024

UVA researchers discover how blood pressure medications affect kidneys

University of Virginia School of Medicine researchers have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood.

21 Nov 2024

Natural fat molecule shows promise for treating diabetic heart disease

Monash University drug discovery researchers have found that a natural fat molecule called ‘lipoxin A4’ (LXA4) could significantly reduce inflammation and improve function for diabetic hearts.

21 Nov 2024

Researchers reveal cellular foundations of functional brain networks in humans

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

21 Nov 2024

First 'blueprint' of human skeletal development offers new insights into bone formation

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone growth.

21 Nov 2024

Electrical stimulation may be essential for healthy tendons, study suggests

A new study by researchers at the University of Galway and the University of Limerick suggests that electrical stimulation might be essential for tendons to maintain their health, offering fresh possibilities in tendon repair and regeneration.

21 Nov 2024

Small brain-penetrating molecule offers hope for treating aggressive brain tumors

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option in combination with temozolomide.

21 Nov 2024

New molecule promotes gut healing and suppresses tumor growth in colorectal cancer

Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer.

21 Nov 2024

Rare genetic mutations in healthy women may be key to breast cancer origins

Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early genetic origins of breast cancer - cancer-like mutations appearing in the cells of healthy women.

21 Nov 2024

New atlas maps 1.6 million human gut cells in unprecedented detail

The most comprehensive cell map of the human gut to date has been created by combining spatial and single-cell data from 1.6 million cells.

21 Nov 2024

Researchers seek to develop noninvasive diagnostics for chronic fatigue syndrome

Chronic fatigue syndrome (CFS) is a complex and long-term illness characterized by extreme fatigue that doesn't improve with rest, and can worsen with physical activity.

21 Nov 2024

Nanoparticle coating enhances cancer drug delivery and reduces side effects

A spoonful of sugar might actually help the medicine go down, according to recent research from the University of Mississippi. And it could reduce the harmful side effects of cancer treatment.

21 Nov 2024

Pcdh8 gene suppression critical for zebrafish notochord formation

Can a single protein-encoding gene determine whether a vertebrate embryo develops normally? Yes, according to Osaka Metropolitan University researchers, who found that suppression of Pcdh8 is essential for the notochord to elongate properly in zebrafish.

21 Nov 2024