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Recommended choline intake during pregnancy improves child's sustained attention

Seven-year-old children performed better on a challenging task requiring sustained attention if their mothers consumed twice the recommended amount of choline during their pregnancy, a new Cornell study has found.

3 Jan 2022

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Drug-induced liver injury (DILI) is an adverse reaction to ingesting a drug, which can appear both in developmental stages, in their clinical use and even after being approved as a drug.

30 Dec 2021

Intestinal organoids used to explain why bats infected with viruses do not succumb to diseases

Experiments attempting to explain why bats can be infected with many viruses at a time without succumbing to diseases such as COVID-19 - knowledge that could help us to reduce the threat to humans of infectious disease - have struggled until now with the fact that live wild bats make poor research subjects.

30 Dec 2021

Exploring the importance of selenium in COVID-19 patients

In a new study, researchers reviewed research on the role that selenium could play in protecting individuals against coronavirus disease 2019.

29 Dec 2021

Combination of rifampicin and resveratrol helps stop dementia, finds study

Dementia is thought to occur when proteins called amyloid-β, tau, and α-synuclein accumulate in the brain and form oligomers. A research group from the Department of Translational Neuroscience, Osaka City University Graduate School of Medicine, had previously shown in a study using mice that the antibiotic rifampicin removes oligomers from the brain and improves cognitive function.

29 Dec 2021

High-fiber diet helps melanoma patients to respond better to immunotherapy

Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration that includes the Oregon State University College of Pharmacy.

24 Dec 2021

Introducing deuterium makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

Holiday Heart Syndrome not associated with ventricular arrhythmias, study finds

The relationship between alcohol and atrial fibrillation has long been referred to as the Holiday Heart Syndrome. An extensive study of the relationship between total alcohol consumption and cardiovascular disease determined that this phenomenon is not associated with ventricular arrhythmias (VAs).

21 Dec 2021

SGLT2 inhibitor empagliflozin can be used to treat insulin resistance in the brain, finds study

Overweight or obesity, an unfavorable distribution of fat in the body and the development of type 2 diabetes are often associated with a reduced effect of the hormone insulin in many organs, including the brain (insulin resistance).

21 Dec 2021

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

In a new study, published on the bioRxiv* preprint server, scientists showed in a mice model that three doses of the same synthetic peptide vaccine, eliciting an exclusive CD8+ T cell response against one SARS-CoV-2 Spike epitope, protected against lethal SARS-CoV-2 infection, in the absence of neutralizing antibodies. Researchers also showed that the third dose resulted in superior generation of effector-memory T cells in the circulation and tissue-resident memory T (TRM) cells.

20 Dec 2021

New study shows how regular exercise protects against fatty liver disease

Exercise not only trains the muscles but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research, Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in particular of the liver mitochondria, can be observed in this process.

20 Dec 2021

Intensive lifestyle intervention benefits individuals with high-risk prediabetes

Intensive lifestyle intervention with plenty of exercise helps people with prediabetes improve their blood glucose levels over a period of years and thus delay or even prevent type 2 diabetes.

20 Dec 2021

Physicians who rely only on liver function test can fail to diagnose alcoholic cirrhosis

A recent study at the Medical University of South Carolina's (MUSC) Digestive Disease Research Core Center (DDRCC) provides insight into why physicians should be cautious when using a certain liver function test to diagnose alcoholic cirrhosis.

20 Dec 2021

Salk researchers win $250,000 award to study cellular, molecular drivers of pancreatic cancer

Professor Ronald Evans and Assistant Professor Dannielle Engle have been granted a 2021 ASPIRE (Accelerating Scientific Platforms and Innovative Research) award to study the cellular and molecular drivers of pancreatic cancer, one of the deadliest cancers with few effective treatment options.

18 Dec 2021

New treatment could be a better option for patients with colon cancer

Targeted radioembolization alongside chemotherapy improved progress-free survival for patients with colon cancer that had metastasized to the liver, according to a study published in the Journal of Clinical Oncology.

17 Dec 2021

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary arteries and ultimately causes the right ventricle of the heart to fail, scientists report.

16 Dec 2021

Therapeutic antibodies deemed ineffective against Omicron variant of SARS-CoV-2

A new study found that the Omicron S protein evades antibodies with a 44-fold higher efficiency than the Delta variant's spike, rendering therapeutic antibodies ineffective and likely negatively impacting antibody protection induced by infection or double vaccination.

16 Dec 2021

Treatment for high blood pressure during pregnancy appears safe and reduces maternal risk

Treatment for high blood pressure during pregnancy appears safe for many women and may reduce maternal risk for severe hypertension without increasing fetal and neonatal risks, according to a new American Heart Association scientific statement published today in the Association's journal Hypertension.

16 Dec 2021

Australian researchers develop new technique to uncover genes involved in congenital heart disease

One in every 100 babies is born with a congenital heart disease (CHD), and CHD is the major cause of death in newborns – however the genetic cause of these developmental disorders is not fully understood, hindering the development of accurate pre-natal genetic testing.

15 Dec 2021

New drug combination may prevent GvHD after stem cell transplantation for blood cancers

A drug combination can safely prevent transplanted stem cells, known as a graft, from attacking the recipient's body, allowing them to develop into healthy new blood and immune cells, a new study shows.

14 Dec 2021

Liver News and Research

Recommended choline intake during pregnancy improves child's sustained attention

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Intestinal organoids used to explain why bats infected with viruses do not succumb to diseases

Exploring the importance of selenium in COVID-19 patients

Combination of rifampicin and resveratrol helps stop dementia, finds study

High-fiber diet helps melanoma patients to respond better to immunotherapy

Introducing deuterium makes drugs to have a longer effect

Holiday Heart Syndrome not associated with ventricular arrhythmias, study finds

SGLT2 inhibitor empagliflozin can be used to treat insulin resistance in the brain, finds study

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

New study shows how regular exercise protects against fatty liver disease

Intensive lifestyle intervention benefits individuals with high-risk prediabetes

Physicians who rely only on liver function test can fail to diagnose alcoholic cirrhosis

Salk researchers win $250,000 award to study cellular, molecular drivers of pancreatic cancer

New treatment could be a better option for patients with colon cancer

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Therapeutic antibodies deemed ineffective against Omicron variant of SARS-CoV-2

Treatment for high blood pressure during pregnancy appears safe and reduces maternal risk

Australian researchers develop new technique to uncover genes involved in congenital heart disease

New drug combination may prevent GvHD after stem cell transplantation for blood cancers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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