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Pioneering research identifies a promising treatment approach for myelofibrosis

Pioneering research into the chronic inflammation often seen in certain blood cancers has identified a promising treatment approach for myelofibrosis, a potentially deadly bone marrow cancer.

9 Nov 2022

OHSU discovery could suggest new avenues to treat symptoms of Parkinson's disease

Researchers at Oregon Health & Science University have discovered that the neurotransmitter adenosine effectively acts as a brake to dopamine, another well-known neurotransmitter involved in motor control.

9 Nov 2022

Does fenofibrate improve clinical outcomes in patients with COVID-19?

Researchers assessed the effect of fenofibrate on acute COVID-19.

9 Nov 2022

The direct and indirect effects of COVID-19 on people with type 1 and type 2 diabetes

A recent study published in The Lancet Diabetes & Endocrinology discussed the impact of COVID-19 on individuals with diabetes.

9 Nov 2022

Study indicates widespread SARS-CoV-2 exposure in wildlife

In a recent study posed to the bioRxiv* preprint server, researchers at Virginia Tech University investigated wildlife exposure to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).

8 Nov 2022

Researchers use lasso-grafting for designing receptor agonists with enhanced pharmacokinetics

Cell growth and repair are stimulated by biomolecules known as cytokines and growth factors. Unfortunately, delivering adequate concentrations of these molecules to the brain for treating neurological conditions like Alzheimer's disease is challenging as they are either cleared out of the blood very quickly or do not penetrate neural tissue effectively.

8 Nov 2022

Researchers decipher key mechanism in the pathogenesis of juvenile Parkinson's

Parkinson's disease affects 3% of population over 65 years old, and the average age of onset is 60. Regarding juvenile Parkinson, which represents the of all Parkison's cases, the disease begins before 40 years old.

8 Nov 2022

Protein complex may present strong therapeutic target for lethal breast cancer

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that a protein complex that governs gene expression (called CoREST) sometimes gets rewired during breast cancer to help estrogen receptor positive (ER+) tumors resist endocrine therapies and become more aggressive.

8 Nov 2022

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

In a recent study published in the journal Cell Host & Microbe, researchers pursued novel approaches that could help find monoclonal antibodies (mAbs) broadly targeting coronaviruses (CoVs), especially genera beta CoVs.

8 Nov 2022

New breakthrough could help spot lung cancer earlier and improve patient outcomes

Scientists investigating the mechanics of the early stages of lung cancer have identified a new potential treatment, which could also aid early detection of the disease.

8 Nov 2022

Cancer drugs work better after vaccination with the Chinese Covid vaccine

Patients with nasopharyngeal cancer are often treated with drugs that activate their immune system against the tumor.

8 Nov 2022

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

Researchers recently measured the neutralizing antibody titers against the wild-type strain of SARS-CoV-2 and the SARS-CoV-2 Omicron subvariants in healthcare workers fully vaccinated with three doses of the Comirnaty vaccine who experienced breakthrough Omicron infections.

8 Nov 2022

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists.

8 Nov 2022

Study uncovers a previously unknown propofol effect in neurons

Propofol is the most commonly used drug to induce general anesthesia. Despite its frequent clinical application, it is poorly understood how propofol causes anesthesia.

7 Nov 2022

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

In a recent study published in the journal Annals of Diagnostic Pathology, researchers in the United States evaluated the impact of coronavirus disease 2019 (COVID-19) on central nervous system (CNS) damage in Alzheimer's disease (AD).

7 Nov 2022

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Ramping up medication doses quickly after being hospitalized for acute heart failure resulted in a lower risk of dying or being readmitted for heart failure within the first six months after discharge, compared to usual care, according to a featured science research presentation today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

The Native Antigen Company expands its range of Omicron antigens to include BA.5 variant

The Native Antigen Company (part of LGC Clinical Diagnostics), one of the world’s leading suppliers of reagents that enables research into vaccines and diagnostics for emerging and endemic infectious diseases, today announced the commercial launch of its latest SARS-CoV-2 antigens for the newly designated Omicron BA.5 variant.

From The Native Antigen Company 7 Nov 2022

Receptor News and Research

Pioneering research identifies a promising treatment approach for myelofibrosis

OHSU discovery could suggest new avenues to treat symptoms of Parkinson's disease

Does fenofibrate improve clinical outcomes in patients with COVID-19?

The direct and indirect effects of COVID-19 on people with type 1 and type 2 diabetes

Study indicates widespread SARS-CoV-2 exposure in wildlife

Researchers use lasso-grafting for designing receptor agonists with enhanced pharmacokinetics

Researchers decipher key mechanism in the pathogenesis of juvenile Parkinson's

Protein complex may present strong therapeutic target for lethal breast cancer

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

New breakthrough could help spot lung cancer earlier and improve patient outcomes

Cancer drugs work better after vaccination with the Chinese Covid vaccine

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

Study uncovers a previously unknown propofol effect in neurons

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

The Native Antigen Company expands its range of Omicron antigens to include BA.5 variant

Scientists map neural pathways that lead to vomiting after eating contaminated food

What were the SARS-CoV-2 seroprevalence estimates for industrial livestock operation workers in the USA for 2021-2022?

Researchers identify therapies for multiple myeloma patients whose cancer relapses after CAR-T

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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