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Study finds novel small molecule that inhibits EboV entry into host cells

Ebola virus (EboV) is the cause of sporadic outbreaks of highly fatal infections in Africa that are unpredictable in onset and rapid in progression. There is no effective vaccine or therapy for EboV infection.

25 Aug 2011

Scientists identify cellular protein that plays a critical role in Ebola virus infection

Research published by two teams of Army scientists and collaborators has identified a cellular protein that plays a critical role in Ebola virus infection.

25 Aug 2011

Researchers discover how antipsychotic drugs manage symptoms of schizophrenia

The classic symptoms of schizophrenia - paranoia, hallucinations, the inability to function socially-can be managed with antipsychotic drugs. But exactly how these drugs work has long been a mystery.

25 Aug 2011

Researchers reveal specific process by which HIV virus infects healthy T cells

A George Mason University researcher team has revealed the specific process by which the HIV virus infects healthy T cells-a process previously unknown. The principal investigator, HIV researcher Yuntao Wu, says he hopes this breakthrough will start a new line on inquiry into how researchers can use this knowledge to create drugs that could limit or halt HIV infection.

25 Aug 2011

Scientists identify critical protein responsible for Ebola virus infection

In separate papers published online in Nature, two research teams report identifying a critical protein that Ebola virus exploits to cause deadly infections. The protein target is an essential element through which the virus enters living cells to cause disease.

25 Aug 2011

NMS Labs develops substance identification tests for nine 'bath salts' compounds

In keeping up with drug abuse trends, NMS Labs has developed substance identification tests for the nine "bath salts" compounds listed in the recently approved PA Senate Bill 1006.

25 Aug 2011

People with Down syndrome have diminished optokinetic, vestibular reflexes

A scientist investigating why those with Down syndrome often have poor balance and motor coordination has found that key eye reflexes are substantially altered.

25 Aug 2011

Researchers discover NPC1 protein as crucial for Ebola virus to enter host cells

Although outbreaks are rare, Ebola virus, the cause of Ebola hemorrhagic fever (EHF), is one of the deadliest known viruses affecting humans. According to the World Health Organization (WHO), approximately 1,850 EHF cases with more than 1,200 deaths have been documented since the virus was identified in 1976.

25 Aug 2011

Psoriasis drug and heart attack risk association unclear: Study

According to American researchers, although a review of published studies reveals that a new and highly effective class of psoriasis drugs does not appear to raise the risk of heart problems, the studies may not have been big enough to detect rare cases.

24 Aug 2011

Parkinson’s disease breakthrough with stem cell research

A new stem cell study has raised hopes for therapy in Parkinson's disease. Researchers said they have, for the first time, generated stem cells from one of the most rapidly-progressing forms of the disease. They said the development will boost research into the condition because it will allow scientists to model the disease in laboratories and help them shed light on why certain nerve cells die. The research was led by the University of Edinburgh in collaboration with University College London (UCL).

24 Aug 2011

Masimo SEDLine brain function monitor receives CE Mark

Masimo announced today that it has received CE Mark for its SEDLine brain function monitor — expanding access to and availability of SEDLine's advanced neuromonitoring technology to hospitals and clinicians across Europe. The

24 Aug 2011

Sarcoma Oncology Center, Aethlon Medical to study ex vivo effectiveness of Hemopurifier

Aethlon Medical, Inc., the pioneer in developing therapeutic filtration devices to address infectious disease and cancer, announced today that it has entered into an agreement with the Sarcoma Oncology Center to study the ex vivo effectiveness of the Aethlon Hemopurifier to remove immunosuppressive exosomes from the blood of advanced-stage cancer patients.

24 Aug 2011

Bacteria tweak their genes and proteins to gain strength

Scientists have discovered that bacteria like E. coli and Salmonella have a sneaky way of making minor alterations to their genes to boost their chances for infection.

24 Aug 2011

HIV-positive pregnant women across Africa face discrimination

HIV-positive women across Africa are facing discrimination, with many "say[ing] they have been pressured – even forced – not to have children because people assume they will infect their babies," PRI's The World reports. "Across the continent, there have been organized efforts to prevent HIV-positive women from having children," The World writes, referencing family planning programs aimed at HIV-positive women in Kenya, Namibia and Uganda.

24 Aug 2011

New Pressurized Olfactory Device shows direct CNS effect of morphine

A simple new approach to nasal drug administration may allow morphine and other strong pain medications to be targeted directly to the central nervous system (CNS), reports an experimental study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Aug 2011

First international conference on developmental, translational and clinical pharmacogenomics

The first international conference hosted by the University of South Florida College of Pharmacy will focus on ways to improve health care by customizing drug prescribing and treatment based on an individual's genetic makeup.

24 Aug 2011

Palliative, hospice care can lessen the suffering cancer brings to patients and families

Being diagnosed with cancer can be devastating, and the treatment can take its toll in physical, emotional, social, and even spiritual ways. Palliative care providers can lessen the suffering cancer brings to patients and their families—both during treatment and at the end of life. Many people don't realize that palliative care to treat symptoms and improve a patient's quality of life can and should be given throughout their illness, not just at the end of life.

24 Aug 2011

Largest ever molecular-genetic study of ependymomas of the cerebellum

Ependymomas are the second most frequent type of malignant brain tumor in children. Ependymoma develops from precursor cells of the tissue that lines the hollow cavities of the brain. Therapy results of ependymoma vary immensely: While in some patients tumor growth comes to a standstill after surgery and radiotherapy, in other children the disease rapidly takes a severe course.

24 Aug 2011

Simvastatin may reduce spinal cord damage from ischemia/reperfusion injury

The cholesterol-lowering drug simvastatin appears to reduce spinal cord injury caused by oxygen deprivation in experimental animals, according to a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Aug 2011

Only 20.6% of Medicaid-covered Ohio youths complete full six month antidepressant treatment

About half of Medicaid-covered children and adolescents in Ohio who are in treatment for depression complete their first three months of prescribed antidepressants, and only one-fifth complete the recommended minimum six-month course of drugs to treat depression, new research suggests.

24 Aug 2011