Protein C News and Research

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POMC neurons suppress appetite, induce weight loss: Research

A protein found in cells throughout the body must be present in a specific set of neurons in the brain to prevent weight gain after chronic feeding on high-calorie meals, new findings from UT Southwestern Medical Center researchers suggest.

7 Jul 2010

Cornerstone reacquires all development, commercial rights to HMGB1 related technology from MedImmune

Cornerstone Therapeutics Inc., a specialty pharmaceutical company focused on acquiring, developing and commercializing significant products primarily for the respiratory and related markets, today announced that the Company has reacquired all development and commercial rights to its high-mobility group box protein 1 (HMGB1) related technology from MedImmune, LLC.

6 Jul 2010

Preclinical efficacy data of Sangamo's ZFN based human stem cell therapy for HIV published

Sangamo BioSciences, Inc. announced the publication of data demonstrating the preclinical efficacy of a human stem cell therapy for human immunodeficiency virus (HIV) based on its proprietary zinc finger DNA-binding protein nuclease (ZFN) technology.

6 Jul 2010

Hope for ovarian cancer patients not responding to conventional chemotherapy

Investigators at the Translational Genomics Research Institute (TGen) have discovered a way that may help ovarian cancer patients who no longer respond to conventional chemotherapy.

6 Jul 2010

Antibody-producing B cells promote atherosclerosis: Study

Antibody-producing B cells promote atherosclerosis in mice, according to a study to be published online on July 5th in the Journal of Experimental Medicine (www.jem.org) These findings came as a surprise, as prior studies had suggested that B cells help protect against the disease.

6 Jul 2010

New blood test eliminates need for surgical lung biopsy for LAM diagnosis

Researchers at the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center have found that a certain blood test can successfully identify lymphangioleiomyomatosis (LAM) in some patients, eliminating the need for surgical lung biopsy to make a diagnosis.

6 Jul 2010

Novel therapy slows tumor growth in 85% of advanced breast cancer patients: Study

A novel therapy designed to attack tumors in patients with a genetic mutation in either BRCA1 or BRCA2, slowed tumor growth in 85 percent of advanced breast cancer patients treated in a small study, researchers report in the July 6 issue of The Lancet.

6 Jul 2010

Clusterin associated with development, severity and progression of Alzheimer's disease: Report

Higher concentrations of clusterin, a protein in the blood plasma, appears to be associated with the development, severity and progression of Alzheimer's disease, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

6 Jul 2010

A20 protein plays protective role in diseases associated with chronic bowel inflammation: Scientists

Scientists associated with VIB (Flanders Institute for Biotechnology) and Ghent University have discovered that A20 protein plays an important protective role in diseases associated with chronic bowel inflammation. This makes A20 into a promising therapeutic target for the development of new anti-inflammatory drugs.

5 Jul 2010

Transplanted beta cells protect themselves by adapting to their new homes

For transplanted beta cells, life is tough. Not only are the insulin-producing cells in a stranger's body, tucked into the liver rather than the pancreas, they are a bit short on oxygen and blood, and they are often exposed to raised levels of glucose.

3 Jul 2010

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Mount Sinai Hospital researchers including Drs. Andras Nagy and Jeff Wrana have discovered new insights into the genesis of stem cells, which will improve the efficiency of stem cell creation for use in tissue regeneration and in the development of new drugs.

3 Jul 2010

Rogue stem cells capable of kick-starting melanoma skin cancer development discovered

Researchers at Stanford University School of Medicine in the US have discovered that rogue stem cells appear to be capable of kick-starting the development of melanoma skin cancer in humans.

3 Jul 2010

Further analysis on Bcl11b gene and T-cell behaviouur from Caltech Biologists

When does a cell decide its particular identity? According to biologists at the California Institute of Technology (Caltech), in the case of T cells-immune system cells that help destroy invading pathogens-the answer is when the cells begin expressing a particular gene called Bcl11b.

3 Jul 2010

People with high levels of vitamin B6 and methionine less likiely to develop lung cancer

People with higher blood levels of vitamin B6 and the amino acid methionine appear to have a lower risk of lung cancer, a French study has found. But more research is needed to understand if higher levels of the nutrients directly protect against the disease.

3 Jul 2010

Exposure to carbon monoxide, air pollution does not increase preterm delivery risk

While pregnant women may worry about the effects of air pollution on their health and that of their developing child, exposure to carbon monoxide and fine particles in the air during pregnancy does not appear to increase the risk of preterm delivery or preeclampsia -- a serious condition that arises only during pregnancy -- according to results of a study headed by a University at Buffalo epidemiologist.

2 Jul 2010

Eli Lilly, Alnara sign definitive merger agreement

Eli Lilly and Company and Alnara Pharmaceuticals, Inc. today announced they have signed a definitive merger agreement whereby Lilly will acquire Alnara, a privately held biotechnology company developing protein therapeutics for the treatment of metabolic diseases. Alnara's lead product in development is liprotamase, a non-porcine pancreatic enzyme replacement therapy (PERT).

2 Jul 2010

Investment report on Arena Pharmaceuticals

MicroStockProfit.com announces an investment report featuring Arena Pharmaceuticals Inc.. The report includes financial, comparative and investment analyses, and recent company news that you need to know to make an educated investment decision.

2 Jul 2010

ISHLT issues first international consensus formulation of standardized nomenclature for CAV

Cardiac allograft vasculopathy (CAV), the major limitation to long term survival after heart transplantation, occurs when blood vessels in a transplanted heart progressively narrow and lead to dysfunction of the heart muscle or sudden death. Ascertaining benefit from appropriate treatment for this condition has been hampered in part because of the lack of a standard nomenclature.

2 Jul 2010

QR Pharma to present clinical data from mechanism of action study in MCI patients at ICAD 2010

QR Pharma, Inc., a developer of novel drugs to treat Alzheimer's disease (AD), announced today that it has been accepted to present a poster on clinical data from its recent mechanism of action study in mild cognitive impaired (MCI) patients at the International Congress on Alzheimer's Disease (ICAD 2010).

2 Jul 2010

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

A protein that helps pack DNA into the cell nucleus has an important role in regulating gene activity, scientists report. The researchers found that the protein, histone H1, also takes part in the formation of ribosomes, the cellular workbenches on which all proteins are made.

2 Jul 2010

Protein C News and Research

POMC neurons suppress appetite, induce weight loss: Research

Cornerstone reacquires all development, commercial rights to HMGB1 related technology from MedImmune

Preclinical efficacy data of Sangamo's ZFN based human stem cell therapy for HIV published

Hope for ovarian cancer patients not responding to conventional chemotherapy

Antibody-producing B cells promote atherosclerosis: Study

New blood test eliminates need for surgical lung biopsy for LAM diagnosis

Novel therapy slows tumor growth in 85% of advanced breast cancer patients: Study

Clusterin associated with development, severity and progression of Alzheimer's disease: Report

A20 protein plays protective role in diseases associated with chronic bowel inflammation: Scientists

Transplanted beta cells protect themselves by adapting to their new homes

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Rogue stem cells capable of kick-starting melanoma skin cancer development discovered

Further analysis on Bcl11b gene and T-cell behaviouur from Caltech Biologists

People with high levels of vitamin B6 and methionine less likiely to develop lung cancer

Exposure to carbon monoxide, air pollution does not increase preterm delivery risk

Eli Lilly, Alnara sign definitive merger agreement

Investment report on Arena Pharmaceuticals

ISHLT issues first international consensus formulation of standardized nomenclature for CAV

QR Pharma to present clinical data from mechanism of action study in MCI patients at ICAD 2010

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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