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GlaxoSmithKline believes there is no liver safety issue with Avandia (rosiglitazone maleate)

GlaxoSmithKline today issued the following response to a petition filed by Public Citizen to the U.S. Food and Drug Administration (FDA) on Avandia (rosiglitazone maleate), a highly effective therapy for treating type 2 diabetes when used in the appropriate patient population.

31 Oct 2008

Pulsed ultrasound used to remote control brain circuits

In a twist on nontraditional uses of ultrasound, a group of neuroscientists at Arizona State University has developed pulsed ultrasound techniques that can remotely stimulate brain circuit activity.

29 Oct 2008

Drinking milk to ease milk allergy?

Giving children with milk allergies increasingly higher doses of milk over time may ease, and even help them completely overcome, their allergic reactions, according to the results of a study led by the Johns Hopkins Children's Center and conducted jointly with Duke University.

29 Oct 2008

FDA grants tentative approval for 75th generic anti-retroviral drug

The Food and Drug Administration within the U.S. Department of Health and Human Services (HHS) has reached the milestone of the 75th anti-retroviral generic drug approved or tentatively approved as part of President Bush's Emergency Plan for AIDS Relief (PEPFAR).

29 Oct 2008

Grapes may aid a bunch of heart risk factors

Could eating grapes help fight high blood pressure related to a salty diet? And could grapes calm other factors that are also related to heart diseases such as heart failure? A new University of Michigan Cardiovascular Center study suggests so.

29 Oct 2008

FDA gets slap on the wrist over chemical BPA

The conclusion by the Food and Drug Administration's (FDA) that the widely used chemical bisphenol-A, or BPA, is safe has been slammed by a panel of experts.

29 Oct 2008

Rice can trigger a severe allergic reaction in babies

According to new research by Australian doctors, contrary to the current view of it as a hypo-allergenic foodstuff, rice can trigger a severe allergic reaction in babies.

29 Oct 2008

FDA statement on release of Bisphenol A (BPA) subcommittee report

We appreciate the hard work and long hours the subcommittee has invested in scientific peer review of the FDA's draft safety assessment of the use of BPA in food contact applications.

29 Oct 2008

High-fat diet could promote the development of Alzheimer's

A team of Université Laval researchers has shown that the main neurological markers for Alzheimer's disease are exacerbated in the brains of mice fed a diet rich in animal fat and poor in omega-3s. Details of the study-which suggests that diets typical of most industrialized countries promote the development of Alzheimer's-are outlined in the latest online edition of Neurobiology of Aging.

28 Oct 2008

FDA warns Bayer HealthCare on over-the-counter aspirin product

The U.S. Food and Drug Administration today sent Warning Letters to Bayer HealthCare concerning two unlawful, over-the-counter (OTC) aspirin products - Bayer Women's Low Dose Aspirin + Calcium (Bayer Women's) and Bayer Aspirin with Heart Advantage (Bayer Heart Advantage).

28 Oct 2008

Selenium and vitamin E supplements do not prevent prostate cancer

Initial, independent review of study data from the Selenium and Vitamin E Cancer Prevention Trial (SELECT), funded by the National Cancer Institute (NCI) and other institutes that comprise the National Institutes of Health shows that selenium and vitamin E supplements, taken either alone or together, did not prevent prostate cancer.

28 Oct 2008

Scientists discover a catalytic antibody that degrades a known appetite stimulant

The antibody works against the gastric hormone ghrelin (pronounced "grell-in"), which has been linked to weight gain and fat storage through its metabolic actions. These findings point towards a potentially novel treatment for obesity that would interfere directly with the some of the biological mechanisms determining weight.

28 Oct 2008

Breastfeeding and reduced risk of childhood obesity - researchers look for behavioral link

Breastfeeding has a number of positive health benefits for baby: it can prevent ear infections and allergies, and lowers the risk of developing respiratory problems. It can also help prevent against obesity later in life, but the reason for this still isn't known.

28 Oct 2008

Griffith University and Pfizer in new partnership to unlock nature's cure for infections

In the quest to develop the next generation of anti-infective medicine, Griffith University and Pfizer, the world's largest research-based pharmaceutical company, announced a leading partnership today.

27 Oct 2008

Eating whole grains lowers heart failure risk

About 5 million people in the United States suffer from heart failure (HF). While some reports indicate that changes to diet can reduce HF risk, few large, prospective studies have been conducted.

27 Oct 2008

In mice, anxiety is linked to immune system

In the first study ever to genetically link the immune system to normal behavior, scientists at Rockefeller and Columbia universities show that mast cells, known as the pharmacologic bombshells of the immune system, directly influence how mice respond to stressful situations.

27 Oct 2008

Re-regulating global finance with the poor in mind

For the poor, finance is always about much more than economics. In practical as well as philosophical terms it is a matter of basic human rights. As the dust begins to settle on the global financial crisis it is certain that all economies will suffer. For the rich, OECD states, stagnation or recessionary losses are predicted, and for the emerging (BRIC) economies of Brazil, Russia, India and China, growth will significantly slow. But it is in the poorest, least developed states that we will likely see the most dramatic effects, simply because they have less to lose.

27 Oct 2008

New gout drug offers hope for those who have exhausted treatment options

Researchers in the U.S. say a new drug effectively treats serious cases of gout - the drug called pegloticase mimics a blood-clearing enzyme missing in humans and helps remove the build up in uric acid, which causes the painful, needle-like crystals to collect around fingers, toes and other joints.

27 Oct 2008

New drugs the next casualty of the credit crunch

Scientists at an international conference have been warned that the next casualty of the credit crunch could be new drugs.

27 Oct 2008

Gardasil safety questioned, CDC urged to back up statement with data

The National Vaccine Information Center (NVIC) is calling on the Centers for Disease Control (CDC) and Food and Drug Administration (FDA) to publicly release the study design, data and names of principal investigators involved in a statement this week maintaining that Gardasil vaccine is safe with no serious side effects.

26 Oct 2008