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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Positive results from PROLOR Biotech's Factor VIIa-CTP preclinical study on hemophilia

PROLOR Biotech, Inc.,, today reported positive results from a comparative study of its biobetter longer-acting version of the hemophilia drug Factor VIIa (Factor VIIa-CTP) in hemophilic mice.

15 Sep 2011

Consensus panel calls for specialized nutrition therapy to manage obesity

A newly published consensus report prepared by a panel of clinical experts, with sponsorship from Nestle Health Science, reveals that there are opportunities to do more to manage the impact of obesity on the delivery of critical care, particularly in the area of nutrition therapy.

15 Sep 2011

Heart specialists reveal how pacemaker works at the biological level

Heart specialists at Johns Hopkins have figured out how a widely used pacemaker for heart failure, which makes both sides of the heart beat together to pump effectively, works at the biological level.

15 Sep 2011

Rac1 protein triggers growth of long 'legs' that could propel melanoma cells to spread

Cancer Research UK scientists have discovered that a protein called Rac1 prompts pigment cells to sprout long 'legs' that could propel skin cancer cells, allowing them to spread, according to research published in Developmental Cell today.

15 Sep 2011

First effective blood-stage vaccine against malaria

Scientists have identified the first effective blood-stage malaria vaccine, according to a New England Journal of Medicine study from University of Maryland School of Medicine researchers, in collaboration with the University of Bamako in Mali, West Africa, and other partners.

15 Sep 2011

Researchers discover several chemical compounds against human prion diseases

In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening the door to potential treatments for human prion diseases.

15 Sep 2011

Teen milk drinkers less likely to suffer from Type 2 diabetes

Developing healthy habits like drinking milk as a teen could have a long-term effect on a woman's risk for type 2 diabetes, according to new research in this month's issue of the American Journal of Clinical Nutrition.

14 Sep 2011

DiscoveryBioMed receives NIDDK grant for Cystic Fibrosis Corrector Ligand Drug Discovery program

DiscoveryBioMed, Inc. (DBM), a human cell-based drug discovery company, learned recently that its Cystic Fibrosis Corrector Ligand (CFCL) Drug Discovery program will be funded by the NIH. The two-year award will focus on validation and prioritization of several lead CFCL chemical classes, drugs that correct the most common cystic fibrosis (CF) disease-causing mutation.

14 Sep 2011

Lucentis receives Health Canada approval to treat vision loss from DME

Health Canada has approved Lucentis (ranibizumab) as a treatment for vision loss resulting from diabetic macular edema, one of the major causes of adult vision loss and an important complication of the growing epidemic of diabetes.

14 Sep 2011

Celecoxib inhibits GSK3 enzyme in lung cancer cells

Several clinical studies have shown that taking the anti-inflammatory drug celecoxib can reduce the risk of developing polyps that lead to colon cancers, at the cost of increasing the risk of heart disease. But what if this tradeoff was not necessary?

14 Sep 2011

Researchers evaluate effect of Terahertz radiation on gene expression in stem cells

Terahertz technologies show promise for myriad medical, military, security, and research applications ranging from the detection of cancer to airport security systems to shipment inspection to spectroscopy. Relatively little is known, however, about the effect of THz radiation on biological systems.

14 Sep 2011

STED microscope reveals that F-actin pervades immunological synapse

Making use of a new "super resolution" microscope that provides sharp images at extremely small scales, scientists have achieved unprecedented views of the immune system in action.

14 Sep 2011

BVES protein may play a role in colon cancer progression

A protein critical in heart development may also play a part in colon cancer progression. Research led by investigators from Vanderbilt-Ingram Cancer Center and the Vanderbilt Eye Institute suggests that the protein BVES (blood vessel endocardial substance) - which also is key in regulating corneal cells - may be a therapeutic target for halting colon cancer metastasis.

14 Sep 2011

Scientists decode new mechanism that regulates cell polarity in epithelial tissues, neurons

In the course of examining the Drosophila tumor suppressor gene (Dlg), scientists at the Helmholtz Zentrum München have succeeded in decoding a new mechanism that regulates cell polarity in epithelial tissues or in neurons in the brain.

14 Sep 2011

A woman's pregnancy outcome can be an indicator of future health conditions

"A woman's pregnancy outcome can be an indicator of future health conditions," stated George R. Saade, M.D., president of the Society for Maternal-Fetal Medicine and professor of obstetrics and gynecology at The University of Texas Medical Branch in Galveston, Texas.

14 Sep 2011

Pure maple syrup may promote a healthy liver

New research conducted at the University of Tokyo suggests that pure maple syrup may promote a healthy liver.

14 Sep 2011

University of Antioquia and IBM partner for Leishmaniasis research

IBM and University of Antioquia's Tropical Disease Study and Control Program (PECET) today announced a joint research project, Drug Search for Leishmaniasis, using computer power from IBM's World Community Grid.

14 Sep 2011

Health Canada approves Afinitor for treatment of brain tumours caused by TSC in children

Families with children suffering from brain tumours caused by an uncommon genetic disorder known as Tuberous Sclerosis Complex (TSC) have new hope with Health Canada's recent conditional approval of a new therapeutic use for the drug Afinitor (everolimus). Afinitor is the first drug therapy approved in Canada for the treatment of brain tumours caused by TSC in patients three years of age and older.

14 Sep 2011

Efficient, economical molecule could speed evaluation of some anti-cancer treatments

Researchers from Boston College have developed a new class of small molecule receptors capable of detecting a lipid molecule that reveals the telltale signs of cellular death, particularly cancer cells targeted by anti-cancer drugs, the team reports in the current electronic edition of the Journal of the American Chemical Society.

14 Sep 2011

ViroPharma initiates Cinryze Phase 2 subcutaneous trial in patients with HAE

ViroPharma Incorporated and Halozyme Therapeutics announced today that ViroPharma has initiated an open-label, multi-dose Phase 2 study to evaluate the safety, and pharmacokinetics and pharmacodynamics of subcutaneous administration of Cinryze in combination with Halozyme's Enhanze technology, a proprietary drug delivery platform using Halozyme's recombinant human hyaluronidase enzyme, in subjects with hereditary angioedema.

14 Sep 2011